Product image of Multicrom (Sodium Cromoglicate) supplied by GNH India

Multicrom

Active Ingredient:
Sodium Cromoglicate
Origin:
EU

Multicrom (Sodium Cromoglicate)

Sodium cromoglicate, the active ingredient in Multicrom, is a mast cell stabilizer presented as an ophthalmic solution for ocular use. It is employed to manage allergic conjunctivitis and related ocular allergic conditions in patients requiring topical therapy.

GNH India supplies Multicrom as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Laboratoires Thea

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Indications & Clinical Uses

Multicrom is a mast cell stabilizer used to treat ocular allergic disorders. It works by reducing the release of histamine and other inflammatory mediators in the eye.

  • Allergic conjunctivitis: alleviates itching, redness, and watery discharge.
  • Seasonal allergic conjunctivitis: controls episodic inflammation during pollen seasons.
  • Vernal keratoconjunctivitis: helps prevent mast‑cell‑mediated flare‑ups and ocular discomfort.

How It Works

  • Sodium cromoglicate stabilizes the membranes of mast cells in the conjunctival and corneal tissues, inhibiting degranulation and the subsequent release of histamine, leukotrienes, and other inflammatory mediators. By preventing this cascade, it reduces ocular inflammation and the symptoms associated with allergic eye disease.

Side Effects

Adverse reactions are generally mild and related to local ocular tolerance.

Common Side Effects

  • Transient eye irritation or burning sensation.
  • Blurred vision shortly after instillation.
  • Mild headache.
  • Taste disturbance (after drainage through nasolacrimal duct).
  • Temporary ocular discomfort.
  • Redness at the instillation site.

Serious or Rare Side Effects

  • Severe allergic reaction (e.g., angioedema of the eyelid).
  • Corneal epithelial defect or ulceration.
  • Persistent ocular edema.
  • Vision loss.
  • Anaphylaxis.
  • Prolonged eye pain requiring medical attention.

Precautions & Warnings

Before using Multicrom, consider the following safety measures.

  • Hypersensitivity: avoid if known allergy to sodium cromoglicate or any formulation component.
  • Ocular infection: do not use during active bacterial, viral, or fungal eye infections.
  • Contact lens wearers: remove lenses before instillation and wait before reinserting.
  • Symptom monitoring: discontinue and seek medical advice if symptoms worsen or persist.
  • Storage: Store at room temperature: keep in the original container, protect from light and moisture.

Avoid Interactions

Multicrom may interact with other ocular or systemic agents. Review the following interaction categories.

Major Interactions (Avoid)

  • Topical ocular anesthetics: concurrent use may increase corneal toxicity.
  • Other mast cell stabilizers: combined use can heighten local irritation.

Moderate Interactions (Monitor Closely)

  • Systemic antihistamines: may reduce perceived efficacy of the ocular preparation.
  • Preservative‑containing eye drops: potential additive irritation.
  • Non‑steroidal anti‑inflammatory eye drops: monitor for increased discomfort.

Frequently Asked Questions

Multicrom is an ophthalmic solution containing sodium cromoglicate, used to treat allergic conjunctivitis and other ocular allergic conditions by stabilizing mast cells and reducing eye inflammation.

Sodium cromoglicate stabilizes mast cell membranes in the conjunctiva and cornea, preventing degranulation and the release of histamine and other inflammatory mediators that cause itching, redness, and swelling.

The dosing regimen for Multicrom is determined by the prescribing clinician based on the severity of the allergic eye condition and patient-specific factors.

Safety data for sodium cromoglicate in pregnancy and lactation are limited. Clinicians should weigh potential benefits against unknown risks before prescribing to pregnant or nursing individuals.

Submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and necessary import documentation.

Compared with antihistamine eye drops, sodium cromoglicate acts upstream by preventing mast‑cell degranulation rather than blocking histamine receptors, offering a complementary mechanism that may be useful when antihistamines alone are insufficient.

Multicrom should be stored at room temperature, kept in its original packaging, protected from light, and stored away from moisture to maintain stability.

Multicrom is applied topically to the affected eye(s) as directed by the prescriber, typically using one or more drops per dose, with hands clean and contact lenses removed before instillation.

Serious risks, though rare, include severe allergic reactions such as angioedema of the eyelid, corneal ulceration, persistent ocular edema, and vision loss. Immediate medical attention is required if these occur.

Individuals with a known hypersensitivity to sodium cromoglicate or any component of the formulation, and those with active ocular infections, should avoid using Multicrom.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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