Product image of Multifloxofta (Ofloxacin) supplied by GNH India

Multifloxofta

Active Ingredient:
Ofloxacin
Origin:
EU

Multifloxofta (Ofloxacin)

Ofloxacin, the active ingredient in Multifloxofta, is a fluoroquinolone antibiotic presented as an ophthalmic solution for ocular use. It treats bacterial infections of the eye, including conjunctivitis and keratitis, in adult and pediatric patients as directed by a healthcare professional.

GNH India supplies Multifloxofta as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to EU quality standards and provides regulatory documentation for cross‑border procurement.

Manufacturer / TM Owner

Fidia Farmaceutici S.P.A

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Indications & Clinical Uses

Multifloxofta, a fluoroquinolone eye drop, is indicated for bacterial infections of the ocular surface.

  • Bacterial conjunctivitis: reduces bacterial load and resolves redness and discharge.
  • Keratitis: eradicates causative bacteria and promotes corneal healing.
  • Other ocular bacterial infections: treats infections such as blepharitis and postoperative endophthalmitis when appropriate.

How It Works

  • Ofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, enzymes essential for DNA replication and transcription. By binding to these targets, it prevents bacterial cell division and leads to bacterial cell death, providing a bactericidal effect against susceptible ocular pathogens.

Side Effects

Ophthalmic administration of Ofloxacin may be associated with local and systemic adverse reactions.

Common Side Effects

  • Stinging or burning sensation at the application site
  • Transient eye redness
  • Blurred vision
  • Mild eye discomfort

Serious or Rare Side Effects

  • Severe allergic reaction (e.g., angioedema, anaphylaxis)
  • Corneal ulceration or perforation
  • Persistent visual loss
  • Tendonitis or tendon rupture (systemic exposure)

Precautions & Warnings

When using Multifloxofta, consider the following safety measures.

  • Hypersensitivity: discontinue if allergic reaction occurs.
  • Viral or fungal eye infections: avoid use as it is ineffective.
  • Contact lens wear: remove lenses during treatment and until symptoms resolve.
  • Pregnancy and lactation: use only if benefits outweigh potential risks, as safety data are limited.
  • Store at room temperature: keep in original container, protect from light and moisture.

Avoid Interactions

Ofloxacin may interact with other medications administered systemically or topically.

Major Interactions (Avoid)

  • Systemic fluoroquinolones: concurrent use may increase risk of tendon toxicity.
  • Antacids, iron, zinc, or magnesium supplements: can reduce systemic absorption if oral ofloxacin is taken.

Moderate Interactions (Monitor Closely)

  • Topical corticosteroids: may mask infection signs and increase bacterial proliferation.
  • Other ophthalmic antibiotics: concurrent use may alter ocular flora.
  • Non‑steroidal anti‑inflammatory eye drops: may increase irritation.

Frequently Asked Questions

Multifloxofta is an ophthalmic solution containing Ofloxacin, prescribed to treat bacterial infections of the eye such as bacterial conjunctivitis, keratitis, and other bacterial ocular conditions. It works by eliminating the causative bacteria, helping to reduce inflammation, discharge, and visual disturbance associated with these infections.

Ofloxacin belongs to the fluoroquinolone class and exerts its antibacterial effect by inhibiting the bacterial enzymes DNA gyrase and topoisomerase IV. These enzymes are essential for DNA replication and transcription; their inhibition stops bacterial cell division, leading to bacterial cell death and clearance of the infection.

The dosing regimen for Multifloxofta is determined by the prescribing clinician based on the type and severity of the ocular infection, patient age, and response to therapy. Typical regimens involve one to two drops per eye at specified intervals, but the exact schedule should always follow the healthcare professional’s instructions.

Safety data for Ofloxacin in pregnancy and lactation are limited, and the product is classified as having an unknown pregnancy category. It should only be used when the potential benefit justifies any potential risk to the fetus or infant, and the decision should be made by the treating physician.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity of Multifloxofta. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Compared with other ophthalmic antibiotics such as chloramphenicol or macrolide eye drops, Ofloxacin offers a broad spectrum of activity against Gram‑negative and Gram‑positive bacteria and has a bactericidal mechanism. It is often chosen for infections where resistant organisms are suspected, though local resistance patterns and patient tolerance guide final selection.

Multifloxofta should be stored at room temperature, preferably below 25 °C, in its original container. Protect the solution from direct light and moisture, and keep the cap tightly closed when not in use. Do not freeze the product, and discard any solution that appears discolored or contains particles.

The product is applied as an eye drop. The patient should wash their hands, tilt the head back, pull down the lower eyelid to create a small pocket, and instill the prescribed number of drops into the conjunctival sac. The eye should be closed gently for a few seconds to allow absorption, and contact lenses should be removed during treatment.

Serious adverse reactions, although rare, include severe allergic responses such as angioedema or anaphylaxis, corneal ulceration or perforation, and systemic effects like tendonitis or tendon rupture. Patients should seek immediate medical attention if they experience sudden vision loss, intense eye pain, swelling, or signs of a systemic allergic reaction.

Multifloxofta should not be used by individuals with a known hypersensitivity to Ofloxacin, other fluoroquinolones, or any component of the formulation. It is also contraindicated for viral, fungal, or allergic eye conditions where an antibacterial agent would be ineffective, and it should be avoided in patients where systemic fluoroquinolone exposure is contraindicated.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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