Product image of Murine Irritation & Redness Relief (Naphazoline Hydrochloride) supplied by GNH India

Murine Irritation & Redness Relief

Active Ingredient:
Naphazoline Hydrochloride
Origin:
EU

Murine Irritation & Redness Relief (Naphazoline Hydrochloride)

Naphazoline, the active ingredient in Murine Irritation & Redness Relief, is an alpha‑adrenergic agonist presented as an ocular solution for topical eye use. It reduces ocular redness and irritation by constricting conjunctival blood vessels, providing rapid relief for patients with eye discomfort.

GNH India supplies Murine Irritation & Redness Relief as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The product complies with EU regulatory standards and is manufactured under strict quality‑assured conditions, ensuring consistent potency and safety.

Manufacturer / TM Owner

Elara Pharmaservices Europe Limited

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Indications & Clinical Uses

Naphazoline acts as an ocular decongestant to treat conditions involving conjunctival vasodilation.

  • Ocular redness: diminishes visible redness by narrowing conjunctival blood vessels.
  • Eye irritation: alleviates discomfort caused by minor irritants or dryness.
  • Conjunctival hyperemia: reduces excessive blood flow and swelling in the conjunctiva.

How It Works

  • Naphazoline selectively stimulates alpha‑adrenergic receptors on the smooth muscle of conjunctival blood vessels. This activation triggers vasoconstriction, decreasing blood flow to the ocular surface and thereby reducing redness, swelling, and associated irritation without affecting intra‑ocular pressure under normal use.

Side Effects

Naphazoline may cause a range of ocular and systemic reactions.

Common Side Effects

  • Stinging or burning sensation upon instillation.
  • Transient blurred vision.
  • Mild headache.
  • Dryness or foreign‑body feeling in the eye.
  • Temporary increase in intra‑ocular pressure (rare).

Serious or Rare Side Effects

  • Allergic reaction such as eyelid swelling, rash, or itching.
  • Severe eye pain or vision loss.
  • Systemic hypertension or rapid heart rate.
  • Persistent corneal ulceration.

Precautions & Warnings

Use of Naphazoline requires attention to specific safety considerations.

  • Pregnancy: safety not established; avoid unless benefits outweigh potential risks.
  • Breastfeeding: unknown; consider possible exposure to the infant.
  • Contact lens wearers: remove lenses before application and wait several minutes before reinserting.
  • Pre‑existing glaucoma or ocular hypertension: use with caution and under medical supervision.
  • Store at ambient temperature: keep in original container, protect from moisture and direct sunlight.

Avoid Interactions

Naphazoline may interact with other ocular or systemic agents.

Major Interactions (Avoid)

  • Concurrent use of other ocular decongestants: additive vasoconstriction can lead to ischemia.
  • Systemic sympathomimetic drugs (e.g., pseudoephedrine): may increase blood pressure.

Moderate Interactions (Monitor Closely)

  • Topical anesthetic eye drops: heightened risk of corneal toxicity.
  • Antihistamine eye drops: may reduce overall efficacy of each product.
  • Beta‑blocker eye drops for glaucoma: monitor intra‑ocular pressure closely.

Frequently Asked Questions

Murine Irritation & Redness Relief is an over‑the‑counter ocular solution containing naphazoline. It is intended to relieve temporary eye redness, irritation, and conjunctival hyperemia by constricting the small blood vessels on the surface of the eye, providing rapid cosmetic and symptomatic improvement.

Naphazoline is a selective alpha‑adrenergic agonist. When applied to the eye, it binds to alpha‑receptors on the smooth muscle of conjunctival vessels, causing them to contract. This vasoconstriction reduces blood flow to the ocular surface, which diminishes redness and swelling associated with minor irritation.

The appropriate dose and frequency are determined by the prescribing clinician. Typically, one drop is placed in the affected eye(s) as needed, not exceeding the maximum daily frequency recommended on the product label, and use should not be prolonged beyond a few days without medical advice.

Safety data for naphazoline in pregnancy and lactation are limited. The product should be used only if the potential benefit justifies any possible risk to the fetus or infant. Women who are pregnant, planning to become pregnant, or breastfeeding should consult their healthcare provider before use.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Naphazoline is comparable to other topical decongestants such as tetrahydrozoline or phenylephrine. All act by vasoconstriction, but naphazoline has a rapid onset and a relatively short duration of action. Choice of agent often depends on clinician preference, patient tolerance, and specific formulation characteristics.

Store the eye‑drop solution at ambient temperature, preferably below 25 °C, in its original container. Protect it from moisture, direct sunlight, and extreme temperature fluctuations. Keep the cap tightly closed when not in use to maintain sterility.

The product is applied topically as an eye drop. After washing hands, tilt the head back, pull down the lower eyelid to create a small pocket, and place one drop into the conjunctival sac. Close the eye gently for a few seconds to allow distribution, then avoid touching the dropper tip to any surface.

Serious adverse events, though rare, include severe allergic reactions (e.g., eyelid swelling, rash), marked eye pain, sudden vision loss, and systemic hypertension. If any of these occur, discontinue use immediately and seek medical attention.

Individuals with known hypersensitivity to naphazoline or any component of the formulation should avoid the product. It is also contraindicated in patients with severe ocular conditions such as acute angle‑closure glaucoma, uncontrolled hypertension, or those who have recently undergone ocular surgery without physician approval.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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