Product image of Myastad (Mycophenolic Acid) supplied by GNH India

Myastad

Active Ingredient:
Mycophenolic Acid
Origin:
EU

Myastad (Mycophenolic Acid)

Mycophenolic Acid, the active ingredient in Myastad, is a immunosuppressant (IMP dehydrogenase inhibitor) presented as an oral formulation for oral use. It is used to prevent organ transplant rejection and to treat lupus nephritis and other autoimmune diseases in adult patients.

GNH India supplies Myastad as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, transplant centres and pharmacies worldwide.

Manufacturer / TM Owner

Stada Arzneimittel Ag

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Indications & Clinical Uses

Myastad is an immunosuppressant used in conditions where suppression of the immune response is required.

  • Organ transplant rejection: helps prevent graft rejection by inhibiting lymphocyte proliferation.
  • Lupus nephritis: reduces renal inflammation and proteinuria in patients with systemic lupus erythematosus.
  • Other autoimmune diseases: controls disease activity in conditions such as rheumatoid arthritis or vasculitis.

How It Works

  • Mycophenolic Acid selectively inhibits inosine monophosphate dehydrogenase, the key enzyme for de novo guanosine nucleotide synthesis. This inhibition lowers intracellular guanosine pools, which preferentially suppresses proliferation of T‑ and B‑lymphocytes, thereby dampening the adaptive immune response.

Side Effects

Myastad may cause a range of adverse reactions, varying from mild to severe.

Common Side Effects

  • Nausea: mild gastrointestinal upset.
  • Diarrhea: loose stools.
  • Headache: transient cranial pain.

Serious or Rare Side Effects

  • Bone marrow suppression: anemia, leukopenia, thrombocytopenia.
  • Severe infections: opportunistic or systemic infections.
  • Renal dysfunction: worsening kidney function.

Precautions & Warnings

When using Myastad, several precautions should be observed.

  • Dose adjustment in renal impairment: reduce dose based on creatinine clearance.
  • Monitor blood counts regularly: watch for leukopenia, anemia, thrombocytopenia.
  • Assess liver function: periodic LFT testing recommended.
  • Avoid use in pregnancy: category D, risk to fetus.
  • Contraception required for women of childbearing potential.
  • Store at room temperature: keep in original container, protect from moisture and light.

Avoid Interactions

Myastad can interact with other medicines, requiring careful management.

Major Interactions (Avoid)

  • Live vaccines: may cause severe infection.
  • Azathioprine: additive bone marrow suppression.
  • Antacids containing aluminum or magnesium: reduce absorption.

Moderate Interactions (Monitor Closely)

  • Rifampin: may decrease mycophenolic acid levels.
  • Cyclosporine or tacrolimus: may increase exposure, monitor levels.
  • Warfarin: potential alteration of INR, monitor coagulation.

Frequently Asked Questions

Myastad is prescribed to prevent organ transplant rejection and to treat lupus nephritis as well as other autoimmune diseases. By suppressing the immune system, it helps maintain graft function after transplantation and reduces disease activity in conditions where the immune response contributes to tissue damage.

Mycophenolic Acid works by selectively inhibiting the enzyme inosine monophosphate dehydrogenase, which is essential for the synthesis of guanosine nucleotides. This blockade limits the proliferation of T‑ and B‑lymphocytes, the cells primarily responsible for adaptive immune responses, thereby providing immunosuppression.

The dose of Myastad is individualized by the prescribing clinician based on factors such as the type of transplant, the patient’s renal and hepatic function, concomitant medications, and the therapeutic goal. No fixed dosing regimen is provided here; the prescriber sets the appropriate regimen.

Myastad is classified as Pregnancy Category D, indicating evidence of risk to the fetus. It is generally not recommended for use during pregnancy unless the potential benefit justifies the risk. Breastfeeding is also discouraged because the drug can be excreted in milk and may affect the infant.

To order Myastad, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request verification of trade or institutional credentials before providing pricing, availability, shipping details and any necessary import documentation.

The primary alternative to Myastad is azathioprine, another oral immunosuppressant. While both suppress lymphocyte proliferation, Myastad offers more selective inhibition of guanosine synthesis, which can result in a different side‑effect profile. Choice between them depends on efficacy, tolerability, drug interactions and individual patient factors.

Myastad should be stored at room temperature, below 25 °C, in its original packaging. Keep the product away from moisture and direct sunlight. Do not store in a refrigerator or freezer unless otherwise specified by the manufacturer.

Myastad is taken orally, usually as a tablet or capsule, with or without food as directed by the prescriber. The exact administration schedule—such as once or twice daily—will be determined by the treating physician based on the clinical indication.

The most serious risks include bone marrow suppression (leading to anemia, leukopenia, or thrombocytopenia), severe or opportunistic infections, and worsening renal function. Patients should be monitored regularly for blood counts, signs of infection and kidney parameters, and should report any concerning symptoms promptly.

Myastad should not be used by individuals with known hypersensitivity to mycophenolic acid or any of its excipients, by pregnant women unless absolutely necessary, and by patients with uncontrolled severe infections. Caution is also advised in those with severe liver or kidney impairment, and the drug should be avoided in patients receiving live vaccines.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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