Product image of Mybracin (Dexamethasone, Tobramycin) supplied by GNH India

Mybracin

Active Ingredient:
Dexamethasone, Tobramycin
Origin:
EU

Mybracin (Dexamethasone, Tobramycin)

Dexamethasone/Tobramycin, the active ingredient in Mybracin, is a corticosteroid/aminoglycoside antibiotic presented as an ophthalmic preparation for ocular use. It combines anti‑inflammatory and antibacterial actions to treat bacterial conjunctivitis, post‑operative ocular inflammation, blepharitis and keratitis in patients as prescribed by an ophthalmologist.

GNH India supplies Mybracin as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Adamed Pharma S.A.

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Indications & Clinical Uses

Mybracin is used to manage ocular infections and inflammation.

  • Bacterial conjunctivitis: reduces bacterial load and associated inflammation.
  • Post‑operative ocular inflammation: controls swelling and discomfort after eye surgery.
  • Blepharitis: alleviates eyelid margin inflammation caused by bacterial overgrowth.
  • Keratitis: treats corneal infection and related inflammatory response.

How It Works

  • Dexamethasone binds glucocorticoid receptors, suppressing inflammatory cytokine production and stabilising lysosomal membranes, while tobramycin attaches to the bacterial 30S ribosomal subunit, causing misreading of mRNA and inhibition of protein synthesis, leading to bacterial cell death.

Side Effects

Adverse reactions may occur with ocular use of Mybracin.

Common Side Effects

  • Burning or stinging sensation at the application site.
  • Transient blurred vision.
  • Foreign body sensation.
  • Mild conjunctival hyperemia.
  • Increased intra‑ocular pressure (monitoring advised).
  • Temporary tearing.

Serious or Rare Side Effects

  • Allergic reactions such as angio‑edema or anaphylaxis.
  • Severe ocular irritation or corneal ulceration.
  • Secondary glaucoma due to prolonged steroid exposure.
  • Systemic aminoglycoside toxicity (rare with topical use).
  • Development of resistant bacterial strains.
  • Persistent or worsening infection.

Precautions & Warnings

Before using Mybracin, consider the following precautions.

  • Pregnancy: consult an ophthalmologist; safety not established.
  • Breastfeeding: limited data; weigh benefits against potential risks.
  • Contact lens wear: avoid during treatment to prevent contamination.
  • Pre‑existing ocular hypertension: monitor intra‑ocular pressure closely.
  • Concurrent systemic aminoglycosides: avoid to reduce risk of nephro‑ or ototoxicity.
  • Store at room temperature: keep in the original container, protect from light and moisture.

Avoid Interactions

Mybracin may interact with other medicines.

Major Interactions (Avoid)

  • Systemic aminoglycosides: additive nephro‑ and ototoxicity.
  • Topical non‑steroidal anti‑inflammatory drugs (NSAIDs): increased risk of corneal melting.
  • Live vaccines: immunosuppression may reduce vaccine efficacy.

Moderate Interactions (Monitor Closely)

  • Cycloplegic agents: may enhance intra‑ocular pressure changes.
  • Anticholinergic eye drops: possible reduced therapeutic effect.
  • Systemic corticosteroids: additive systemic steroid effects may occur.

Frequently Asked Questions

Mybracin is an ophthalmic combination of dexamethasone and tobramycin indicated for bacterial conjunctivitis, post‑operative ocular inflammation, blepharitis and keratitis. It provides both anti‑inflammatory and antibacterial effects to help resolve infection‑related eye conditions.

Dexamethasone acts as a glucocorticoid receptor agonist, suppressing inflammatory cytokines and stabilising cell membranes. Tobramycin, an aminoglycoside, binds to the bacterial 30S ribosomal subunit, causing misreading of mRNA and halting protein synthesis, which leads to bacterial cell death.

The dosing regimen for Mybracin is determined by the prescribing ophthalmologist based on the specific condition, severity and patient factors. Typical use involves instilling the recommended number of drops into the affected eye(s) as directed on the prescription label.

Safety data for Mybracin in pregnancy and lactation are limited. It should be used only if the potential benefit justifies any possible risk to the fetus or infant, and this decision must be made by the treating eye‑care professional.

To order Mybracin, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Mybracin combines a corticosteroid with an aminoglycoside, offering both anti‑inflammatory and antibacterial activity in a single formulation. Compared with single‑agent antibiotics, it reduces the need for multiple drops, but clinicians must consider steroid‑related risks such as intra‑ocular pressure elevation.

Store Mybracin at room temperature, preferably below 25 °C. Keep the vial in its original packaging, protect it from light and moisture, and ensure the cap is tightly closed when not in use.

Mybracin is applied topically to the eye. The patient should wash hands, tilt the head back, pull down the lower eyelid, and instill the prescribed number of drops into the conjunctival sac. The eye should be closed gently for a few seconds to allow absorption.

Serious risks include allergic reactions such as angio‑edema, secondary glaucoma from prolonged steroid exposure, corneal ulceration, and rare systemic toxicity from the aminoglycoside component. Any sudden vision changes, severe pain or swelling should prompt immediate medical attention.

Mybracin should be avoided in patients with known hypersensitivity to dexamethasone, tobramycin or any excipients, in viral or fungal eye infections, and in individuals with uncontrolled ocular hypertension or glaucoma unless closely monitored by an eye specialist.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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