Product image of Mybufen (Ibuprofen) supplied by GNH India

Mybufen

Active Ingredient:
Ibuprofen
Origin:
EU

Mybufen (Ibuprofen)

Ibuprofen, the active ingredient in Mybufen, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral dosage form for oral use. It treats mild to moderate pain, reduces fever, and alleviates inflammatory conditions such as arthritis in adults and children when appropriate.

GNH India supplies Mybufen as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable sourcing for global healthcare providers. Our distribution network ensures timely delivery and regulatory compliance across multiple regions.

Manufacturer / TM Owner

Bluefish Pharmaceuticals Ab

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Indications & Clinical Uses

  • Ibuprofen acts as an analgesic, antipyretic and anti‑inflammatory agent, providing symptom relief across several common conditions.
  • Mild to moderate pain: Relieves headaches, dental pain, menstrual cramps, musculoskeletal aches and other acute discomforts.
  • Fever: Lowers elevated body temperature associated with infections or inflammatory processes.
  • Inflammatory conditions such as osteoarthritis and rheumatoid arthritis: Decreases joint swelling, stiffness and pain to improve mobility.

How It Works

  • Ibuprofen exerts its effect by non‑selectively inhibiting cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, which reduces the conversion of arachidonic acid to prostaglandins. The decreased prostaglandin synthesis diminishes inflammation, pain signaling and the hypothalamic set‑point for temperature, resulting in analgesic, antipyretic and anti‑inflammatory actions.

Side Effects

Ibuprofen may cause a range of adverse reactions, varying from mild and transient to serious and infrequent.

Common Side Effects

  • Gastrointestinal discomfort such as nausea, dyspepsia or abdominal pain
  • Headache or dizziness
  • Mild skin rash or itching
  • Elevated blood pressure in susceptible individuals

Serious or Rare Side Effects

  • Severe gastrointestinal bleeding or ulceration
  • Renal impairment or acute kidney injury
  • Anaphylactic reactions including swelling of the face, throat or airway

Precautions & Warnings

  • When using ibuprofen, consider the following safety measures to minimize risks and ensure appropriate use.
  • Assess renal function: Avoid use in patients with severe kidney disease or dehydration.
  • Monitor gastrointestinal risk: Use lowest effective dose in individuals with history of ulcers or bleeding.
  • Avoid in late pregnancy: Contraindicated during third trimester due to fetal risks.
  • Check for cardiovascular disease: Use cautiously in patients with hypertension or heart failure.
  • Store at ambient temperature: Keep below 25°C in original container, protect from moisture.

Avoid Interactions

Ibuprofen can interact with several medicines, altering their effectiveness or increasing adverse effect potential.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased bleeding risk
  • Selective COX‑2 inhibitors (e.g., celecoxib): additive gastrointestinal toxicity
  • High‑dose aspirin: enhanced renal toxicity

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: may reduce antihypertensive effect and affect kidney function
  • Lithium: ibuprofen can raise lithium levels
  • Methotrexate: reduced clearance leading to toxicity

Frequently Asked Questions

Mybufen contains ibuprofen, an over‑the‑counter NSAID that is commonly used to relieve mild to moderate pain, reduce fever, and manage inflammatory conditions such as osteoarthritis or rheumatoid arthritis.

Ibuprofen works by non‑selectively blocking the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which reduces the production of prostaglandins. Lower prostaglandin levels diminish inflammation, pain signaling, and the hypothalamic response that raises body temperature.

The appropriate dose of Mybufen is determined by a qualified healthcare professional based on the individual’s age, weight, condition being treated, and any other medical considerations. Patients should follow the prescriber’s instructions and not exceed the recommended amount.

Ibuprofen is classified as pregnancy category B, indicating that it is generally considered safe in the first two trimesters when used as directed. However, it should be avoided in the third trimester. Breastfeeding mothers should consult a physician, as small amounts can pass into milk.

To place an order, submit an enquiry on the Mybufen product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request trade or institutional credentials before providing pricing, availability, shipping details and import documentation.

Both ibuprofen (Mybufen) and naproxen belong to the NSAID class and share similar mechanisms of COX inhibition. Ibuprofen generally has a shorter half‑life, requiring more frequent dosing, while naproxen provides longer‑lasting relief but may have a higher risk of gastrointestinal irritation in some patients.

Mybufen should be stored at ambient temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed to maintain stability.

Mybufen is taken orally, usually with a full glass of water. It can be taken with or without food, although taking it with food may reduce gastrointestinal discomfort for some individuals.

Serious risks include gastrointestinal bleeding or ulceration, severe kidney injury, and rare but life‑threatening allergic reactions such as anaphylaxis. Patients with a history of ulcer disease, renal impairment, or cardiovascular disorders should use Mybufen only under medical supervision.

Mybufen should be avoided by individuals with known hypersensitivity to ibuprofen or other NSAIDs, those in the third trimester of pregnancy, patients with active gastrointestinal bleeding, severe renal or hepatic impairment, and anyone taking anticoagulants without physician guidance.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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