Product image of Mycoapaisyl (Econazole Nitrate) supplied by GNH India

Mycoapaisyl

Active Ingredient:
Econazole Nitrate
Origin:
EU

Mycoapaisyl (Econazole Nitrate)

Econazole nitrate, the active ingredient in Mycoapaisyl, is an imidazole antifungal presented as a topical formulation for cutaneous use. It is indicated for the treatment of dermatophyte infections such as tinea corporis, tinea cruris, tinea pedis, as well as candidal skin infections, and is used in both adult and pediatric patients.

GNH India supplies Mycoapaisyl as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, with distribution aligned to EU regulatory standards. The company ensures product quality through rigorous quality‑control procedures and provides reliable logistics for global customers.

Manufacturer / TM Owner

P&g Health France

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Indications & Clinical Uses

  • Econazole nitrate is a topical imidazole antifungal that acts on fungal skin infections.
  • Dermatophyte infections (tinea corporis, tinea cruris, tinea pedis): reduces fungal growth and promotes resolution of skin lesions.
  • Candidal skin infections (cutaneous candidiasis): alleviates erythema, itching and clears the infection.
  • Superficial fungal infections (e.g., tinea versicolor): limits proliferation of Malassezia species and improves skin appearance.

How It Works

  • Econazole nitrate inhibits ergosterol synthesis by blocking the fungal enzyme lanosterol 14α‑demethylase. This disruption compromises the integrity of the fungal cell membrane, leading to increased permeability and ultimately cell death. By targeting a key step in the sterol biosynthetic pathway, the drug provides a fungistatic to fungicidal effect against a broad range of dermatophytes and yeasts when applied to the skin.

Side Effects

Adverse reactions are generally limited to the application site.

Common Side Effects

  • Skin irritation or burning sensation
  • Itching or pruritus at the site
  • Redness or erythema
  • Dryness or peeling of the treated skin

Serious or Rare Side Effects

  • Severe allergic reaction such as urticaria or angio‑edema
  • Extensive skin rash or exfoliative dermatitis
  • Anaphylactic shock or systemic hypersensitivity

Precautions & Warnings

  • When using Mycoapaisyl, observe the following precautions to minimize risks.
  • Avoid application on broken or inflamed skin: limit use to intact epidermis.
  • Do not apply to eyes, mucous membranes or genital mucosa: avoid irritation.
  • Use only external application: do not ingest or inject.
  • Keep out of reach of children: store safely to prevent accidental exposure.
  • Discontinue use and seek medical advice if severe irritation or allergic signs develop.
  • Store at room temperature: keep in the original container, protect from moisture and light.

Avoid Interactions

Topical econazole may interact with other agents applied to the same skin area.

Major Interactions (Avoid)

  • Concurrent use with other irritating topical products (e.g., strong corticosteroids) may increase skin irritation.
  • Application together with other antifungal creams can cause additive local reactions.

Moderate Interactions (Monitor Closely)

  • Use with systemic azole antifungals may enhance overall antifungal exposure if large skin areas are treated.
  • Occlusive dressings over the treated area can increase absorption and risk of local side effects.
  • Co‑application with alcohol‑based products may affect drug stability.

Frequently Asked Questions

Mycoapaisyl contains econazole nitrate and is indicated for the topical treatment of dermatophyte infections such as tinea corporis, tinea cruris and tinea pedis, as well as superficial candidal skin infections. It works on the skin surface to eliminate the fungi responsible for these conditions.

Econazole nitrate blocks the fungal enzyme lanosterol 14α‑demethylase, which is essential for synthesising ergosterol, a key component of the fungal cell membrane. By preventing ergosterol formation, the drug disrupts membrane integrity, leading to increased permeability and ultimately fungal cell death.

The dosage and frequency of Mycoapaisyl are determined by the prescribing healthcare professional based on the type and severity of the infection, the patient’s age and the area of skin involved. Patients should follow the prescriber’s instructions and the product label.

Safety data for econazole nitrate in pregnancy and lactation are limited, and the product’s classification is not specified. Healthcare providers should evaluate the potential benefits against any possible risks before prescribing Mycoapaisyl to pregnant or nursing individuals.

To request Mycoapaisyl, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Econazole nitrate belongs to the imidazole class and offers broad‑spectrum activity against dermatophytes and yeasts. Compared with allylamine agents such as terbinafine, econazole has a similar efficacy for many superficial infections but may differ in dosing frequency and potential for local irritation. Choice of therapy should be guided by the specific pathogen, infection site and patient tolerance.

Mycoapaisyl should be stored at room temperature, preferably below 25 °C, in its original packaging. The container should be kept tightly closed, protected from moisture and direct sunlight to maintain product stability.

The cream or ointment is applied thinly to the affected skin area, usually twice daily, after washing and gently drying the site. The medication should be rubbed in gently until fully absorbed, and hands should be washed after application to avoid inadvertent contact with eyes or mucous membranes.

Although uncommon, serious adverse reactions can include severe allergic responses such as urticaria, angio‑edema, or anaphylaxis, as well as extensive skin rash or exfoliative dermatitis. Patients should discontinue use and seek immediate medical attention if they experience swelling, difficulty breathing, or widespread skin eruptions.

Mycoapaisyl should not be used on broken, inflamed or infected skin that is not of fungal origin, nor should it be applied to the eyes, mucous membranes or genital mucosa. Individuals with a known hypersensitivity to econazole nitrate or any component of the formulation should avoid its use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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