Product image of Mycohydralin (Clotrimazole) supplied by GNH India

Mycohydralin

Active Ingredient:
Clotrimazole
Origin:
EU

Mycohydralin (Clotrimazole)

Clotrimazole, the active ingredient in Mycohydralin, is a azole antifungal presented as a topical formulation for cutaneous and vaginal use. It treats dermatophyte skin infections and vaginal candidiasis in adults and adolescents.
GNH India supplies Mycohydralin as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Bayer Healthcare

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Indications & Clinical Uses

Mycohydralin, an azole antifungal, is employed to treat fungal infections of the skin and mucous membranes.

  • Tinea corporis (ringworm of the body): reduces fungal growth and relieves itching and redness.
  • Tinea cruris (jock itch): clears the infection and improves comfort in the groin area.
  • Tinea pedis (athlete's foot): eliminates the causative fungus and restores normal skin condition.
  • Vaginal candidiasis: eradicates Candida species and alleviates discharge and irritation.

How It Works

  • Clotrimazole inhibits ergosterol synthesis by blocking the fungal cytochrome P450 enzyme lanosterol 14α‑demethylase. This disruption compromises the fungal cell membrane, leading to increased permeability and ultimately cell death, thereby halting the spread of infection.

Side Effects

Adverse reactions may occur with topical clotrimazole use.

Common Side Effects

  • Local itching: mild irritation at the application site.
  • Burning sensation: transient warmth or stinging.
  • Redness: mild erythema of the treated area.
  • Dryness or peeling: superficial skin changes.

Serious or Rare Side Effects

  • Severe allergic reaction: swelling, hives, or difficulty breathing.
  • Contact dermatitis: intense rash or blistering requiring medical attention.

Precautions & Warnings

Before using Mycohydralin, consider the following safety measures.

  • Allergy assessment: avoid if known hypersensitivity to clotrimazole or other azoles.
  • Open wounds: do not apply to extensive broken skin or mucosal lesions.
  • Pediatric use: consult a healthcare professional before treating children.
  • Pregnancy and lactation: discuss potential risks with a physician.
  • Store at ambient temperature: keep below 25 °C, in the original packaging, protected from moisture and direct sunlight.

Avoid Interactions

Clotrimazole may interact with other substances applied to the skin or mucosa.

Major Interactions (Avoid)

  • Concurrent use of other topical antifungals: may increase irritation risk.
  • Topical corticosteroids: can reduce antifungal efficacy.

Moderate Interactions (Monitor Closely)

  • Occlusive dressings: may enhance absorption and local side effects.
  • Alcohol‑based cleansers: could affect drug stability on the skin.
  • Herbal or cosmetic products: assess for potential skin reactions.

Frequently Asked Questions

Mycohydralin contains clotrimazole and is indicated for common fungal skin infections such as tinea corporis, tinea cruris, and tinea pedis, as well as for vaginal candidiasis caused by Candida species.

Clotrimazole blocks the fungal enzyme lanosterol 14α‑demethylase, preventing ergosterol synthesis. This weakens the fungal cell membrane, leading to loss of cell integrity and death of the fungus.

The dosing regimen for Mycohydralin is determined by the prescribing healthcare professional based on the infection type, severity, and patient characteristics. Patients should follow the prescriber’s instructions.

Safety data for clotrimazole in pregnancy and lactation are limited. Women who are pregnant, planning pregnancy, or breastfeeding should discuss potential risks and benefits with their physician before using Mycohydralin.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Mycohydralin (clotrimazole) belongs to the azole class, offering broad‑spectrum activity against dermatophytes and Candida. Compared with allylamine agents such as terbinafine, azoles have a different mechanism and are often preferred for mucosal infections like vaginal candidiasis.

Store Mycohydralin at ambient temperature, preferably below 25 °C. Keep the product in its original container, protect it from moisture, heat, and direct sunlight to maintain stability.

Apply a thin layer of the product to the affected skin or vaginal area as directed by a healthcare professional, typically twice daily for the prescribed duration. Wash hands before and after application unless treating the hands themselves.

Serious risks include severe allergic reactions such as anaphylaxis, and contact dermatitis that may present with extensive rash, swelling, or blistering. Immediate medical attention is required if these symptoms develop.

Individuals with known hypersensitivity to clotrimazole or any other azole antifungal should avoid Mycohydralin. It is also contraindicated on extensive broken skin or mucosal lesions without medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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