Product image of Mycohydralin (Clotrimazole) supplied by GNH India

Mycohydralin

Active Ingredient:
Clotrimazole
Origin:
EU

Mycohydralin (Clotrimazole)

Clotrimazole, the active ingredient in Mycohydralin, is an imidazole antifungal presented as a vaginal formulation for local use. It treats vulvovaginal candidiasis in women by targeting fungal growth within the vaginal mucosa, helping to relieve itching, discharge, and irritation.

GNH India supplies Mycohydralin as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies, clinics and other healthcare institutions worldwide.

Manufacturer / TM Owner

Bayer Healthcare

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Indications & Clinical Uses

Clotrimazole is an imidazole antifungal used to treat infections of the vaginal mucosa caused by Candida species.

  • Vulvovaginal candidiasis (acute): reduces fungal load and alleviates symptoms such as itching, burning, and abnormal discharge.
  • Recurrent vulvovaginal candidiasis (maintenance therapy): helps prevent recurrence when used as directed by a healthcare professional.
  • Vaginal yeast infection (non‑pregnant women): provides rapid symptom relief and eradicates the causative yeast.

How It Works

  • Clotrimazole exerts its antifungal activity by inhibiting the enzyme lanosterol 14α‑demethylase, a key step in ergosterol synthesis. This disruption compromises the fungal cell membrane integrity, leading to impaired growth and eventual cell death of susceptible Candida species.

Side Effects

Clotrimazole may cause local adverse reactions when applied vaginally.

Common Side Effects

  • Vaginal irritation or burning sensation.
  • Itching or mild pruritus.
  • Unusual vaginal discharge.
  • Unpleasant odor from the application site.
  • Mild abdominal discomfort.
  • Temporary increased vaginal moisture.

Serious or Rare Side Effects

  • Allergic reaction with swelling, rash, or hives.
  • Severe skin reactions such as Stevens‑Johnson syndrome.
  • Liver enzyme abnormalities (rare).
  • Anaphylaxis (very rare).

Precautions & Warnings

Before using Mycohydralin, consider the following safety measures.

  • Pregnancy: consult a healthcare provider before use.
  • Breastfeeding: discuss potential risks with a physician.
  • Known allergy to clotrimazole or other imidazoles: avoid use.
  • Concurrent vaginal medications: do not use simultaneously without professional advice.
  • Severe hepatic impairment: use with caution under medical supervision.
  • Store at below 25°C: keep in the original packaging, protect from moisture and heat.

Avoid Interactions

Clotrimazole can interact with other medicines; monitor the following.

Major Interactions (Avoid)

  • Systemic azole antifungals (e.g., fluconazole): increased risk of toxicity.
  • Terbinafine: potential antagonistic effect reducing efficacy.

Moderate Interactions (Monitor Closely)

  • Topical corticosteroids: may diminish clotrimazole absorption.
  • Oral contraceptives: possible slight reduction in effectiveness.
  • Antacids: generally no significant interaction, but monitor symptoms.
  • Alcohol: no known direct interaction, but advise moderation.

Frequently Asked Questions

Mycohydralin is a vaginal formulation containing clotrimazole, an imidazole antifungal. It is used to treat vulvovaginal candidiasis, commonly known as a yeast infection, by eliminating the Candida fungi that cause symptoms such as itching, burning, and abnormal discharge.

Clotrimazole works by inhibiting the fungal enzyme lanosterol 14α‑demethylase, which is essential for ergosterol synthesis. Without ergosterol, the fungal cell membrane becomes defective, leading to impaired growth and death of the Candida organisms responsible for vaginal infections.

The dosage of Mycohydralin is determined by the prescribing healthcare professional based on the specific formulation and severity of infection. Patients should follow the exact instructions provided on the prescription label or by their clinician.

Safety of clotrimazole during pregnancy or while breastfeeding has not been definitively established. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their healthcare provider before using Mycohydralin.

To order Mycohydralin, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Mycohydralin contains clotrimazole, an imidazole class antifungal, which is widely used for vaginal yeast infections. Compared with polyene agents such as nystatin, clotrimazole generally offers a broader spectrum against Candida species and a convenient vaginal dosage form, though choice depends on individual patient factors and clinician preference.

Mycohydralin should be stored at temperatures below 25 °C, in its original packaging, protected from moisture and direct heat. Keep the product out of reach of children and avoid exposing it to excessive humidity or sunlight.

Mycohydralin is applied directly into the vagina using the supplied applicator or as instructed by a healthcare professional. The patient should lie down for a few minutes after insertion to allow proper distribution of the medication across the vaginal mucosa.

Serious risks, though rare, include severe allergic reactions such as rash, swelling, or anaphylaxis, and rare skin conditions like Stevens‑Johnson syndrome. Patients should seek immediate medical attention if they experience any signs of a severe hypersensitivity reaction.

Individuals with a known hypersensitivity to clotrimazole, other imidazole antifungals, or any component of the formulation should avoid using Mycohydralin. Additionally, patients with severe liver disease should use it only under close medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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