Product image of Mycomycen (Ciclopirox) supplied by GNH India

Mycomycen

Active Ingredient:
Ciclopirox
Origin:
EU

Mycomycen (Ciclopirox)

ciclopirox, the active ingredient in Mycomycen, is an antifungal presented as a topical formulation for skin use. It treats superficial fungal infections such as athlete’s foot (tinea pedis), ringworm (tinea corporis), jock itch (tinea cruris), onychomycosis and candidal skin infections in adults and children. The medication is applied directly to the affected area, allowing the active compound to penetrate the skin and nail layers. Its broad spectrum activity covers dermatophytes, yeasts and some molds, making it a versatile option for dermatological practice.

GNH India supplies Mycomycen as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Verisfield S.M.S.A

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Indications & Clinical Uses

Mycomycen (ciclopirox) is used to treat dermatophyte and yeast infections of the skin and nails.

  • Tinea pedis: reduces itching and clears fungal infection of the feet.
  • Tinea corporis: eliminates ring‑shaped lesions caused by dermatophytes on the body.
  • Tinea cruris: relieves inflammation and eradicates fungal growth in the groin area.
  • Onychomycosis: improves nail appearance by inhibiting fungal growth within the nail plate.
  • Candidiasis: treats cutaneous candidal infections, reducing redness and discharge.

How It Works

  • Ciclopirox exerts its antifungal effect by chelating polyvalent cations such as Fe³⁺ and Al³⁺, thereby inhibiting the activity of metal‑dependent enzymes required for sterol synthesis and cellular respiration. This disruption impairs fungal cell membrane integrity and interferes with energy production, leading to inhibition of growth and eventual cell death. Additionally, the drug interferes with peroxidase activity and disrupts the synthesis of essential proteins, further compromising fungal viability.

Side Effects

Topical ciclopirox may cause local skin reactions, which are usually mild and transient, while systemic absorption can rarely produce more serious events that require medical attention.

Common Side Effects

  • Burning sensation at application site.
  • Itching or pruritus.
  • Redness or erythema.
  • Dryness or scaling of skin.
  • Stinging or tingling.
  • Swelling of the treated area.
  • Mild pain at the site.

Serious or Rare Side Effects

  • Allergic contact dermatitis.
  • Severe skin irritation or ulceration.
  • Systemic hypersensitivity reactions.
  • Hepatic enzyme elevation (rare).
  • Secondary bacterial infection of treated area.
  • Photosensitivity reactions.
  • Persistent edema.

Precautions & Warnings

When using Mycomycen, consider the following precautions to ensure safe and effective treatment.

  • Assess for hypersensitivity: confirm no known allergy to ciclopirox or formulation components.
  • Avoid application on extensive broken skin: limit use to intact or mildly irritated areas.
  • Do not apply near eyes or mucous membranes: prevent accidental irritation.
  • Use with caution in children under two years: pediatric safety not fully established.
  • Discontinue if severe irritation or allergic reaction occurs: seek medical advice promptly.
  • Store at room temperature: keep in original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Ciclopirox has a low potential for systemic drug interactions, but certain topical co‑applications may affect its safety or efficacy.

Major Interactions (Avoid)

  • Concurrent use with other topical antifungals: may increase risk of skin irritation.
  • Occlusive dressings over treated area: enhances absorption and could raise local adverse effects.
  • Phototoxic agents applied to same site: may exacerbate skin reactions.

Moderate Interactions (Monitor Closely)

  • Co‑application with corticosteroid creams: may mask irritation signs.
  • Use with topical antibiotics: monitor for secondary infection.
  • Combination with keratolytic agents (e.g., salicylic acid): may alter drug penetration.

Frequently Asked Questions

Mycomycen contains ciclopirox and is indicated for the topical treatment of superficial fungal infections such as athlete’s foot (tinea pedis), body ringworm (tinea corporis), jock itch (tinea cruris), nail fungus (onychomycosis) and cutaneous candidiasis. It is applied to the affected skin or nail area to reduce fungal growth and alleviate associated symptoms.

Ciclopirox interferes with fungal metabolism by chelating essential metal ions, which blocks enzymes needed for sterol synthesis and cellular respiration. This disruption damages the fungal cell membrane and hampers energy production, ultimately inhibiting fungal growth and leading to cell death. The mechanism also affects peroxidase activity and protein synthesis within the pathogen.

The dosage regimen for Mycomycen is determined by the prescribing healthcare professional based on the specific infection, its severity, and the patient’s age. Typically, a thin layer is applied to the affected area once or twice daily, but the exact frequency and duration should follow the prescriber’s instructions.

Safety data for ciclopirox in pregnancy and lactation are limited. It should only be used if the potential benefit justifies any possible risk to the fetus or infant. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss the use of Mycomycen with their healthcare provider before starting treatment.

To place an order, submit an enquiry on the Mycomycen product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide. After receiving the request, the sales team will verify trade or institutional credentials, then provide pricing, availability, shipping details (including any cold‑chain requirements) and assist with import documentation.

Mycomycen (ciclopirox) offers a broad spectrum of activity against dermatophytes, yeasts and some molds, and is applied topically. Compared with allylamine agents such as terbinafine, ciclopirox has a different mechanism—metal‑ion chelation—providing an alternative for patients who may not tolerate or respond to azole or allylamine therapies. Choice of agent depends on infection type, location, patient factors and clinician preference.

Mycomycen should be stored at room temperature, preferably below 25 °C. Keep the product in its original container, protect it from moisture, direct sunlight and extreme heat. Ensure the cap is tightly closed after each use to maintain stability and potency.

Mycomycen is a topical preparation intended for external use only. Apply a thin layer to the clean, dry affected skin or nail surface, gently massaging it in. Wash hands before and after application, and avoid contact with eyes, mucous membranes and open wounds unless directed by a healthcare professional.

While most reactions are mild, serious adverse events can include allergic contact dermatitis, severe skin irritation or ulceration, systemic hypersensitivity reactions, and, rarely, hepatic enzyme elevations. If any signs of a severe reaction appear—such as widespread rash, swelling, fever, or liver-related symptoms—stop use immediately and seek medical attention.

Mycomycen should not be used by individuals with a known hypersensitivity to ciclopirox or any component of the formulation. It is also contraindicated on large areas of broken or severely inflamed skin, and should be used with caution in children under two years of age unless specifically advised by a clinician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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