Product image of Myconail (Ciclopirox) supplied by GNH India

Myconail

Active Ingredient:
Ciclopirox
Origin:
EU

Myconail (Ciclopirox)

Ciclopirox, the active ingredient in Myconail, is an antifungal presented as a topical formulation for topical use. It treats fungal skin infections such as tinea corporis, tinea pedis, tinea cruris, cutaneous candidiasis, and onychomycosis in adults and children and is marketed across European Union member states with a focus on dermatological care.

GNH India supplies Myconail as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory‑approved batches to meet global demand.

Manufacturer / TM Owner

Laboratoires Bailleul S.A.

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Indications & Clinical Uses

  • Myconail (ciclopirox) is used to treat fungal skin conditions by inhibiting fungal growth.
  • Dermatophytosis (tinea corporis, pedis, cruris): clears infection and relieves itching, scaling and redness.
  • Candidiasis of the skin: reduces yeast proliferation and promotes resolution of erythematous lesions.
  • Onychomycosis: facilitates clearance of nail fungus and improves nail appearance.

How It Works

  • Ciclopirox chelates polyvalent metal ions such as Fe³⁺ and Al³⁺, thereby inhibiting metal‑dependent enzymes essential for fungal cell membrane synthesis and metabolic processes. This disruption impairs the production of sterols and other vital components, leading to loss of cell integrity and ultimately fungal cell death. The chelation also interferes with oxidative phosphorylation and hampers the activity of peroxidases, further compromising fungal viability.

Side Effects

Topical ciclopirox may cause local skin reactions, ranging from mild irritation to rare severe hypersensitivity.

Common Side Effects

  • Itching or pruritus at the application site
  • Burning sensation
  • Redness or erythema
  • Dryness or flaking of skin
  • Mild irritation or stinging
  • Scaling or peeling

Serious or Rare Side Effects

  • Severe allergic reaction (angioedema, anaphylaxis)
  • Contact dermatitis with blistering
  • Bullous skin eruptions
  • Stevens‑Johnson syndrome
  • Toxic epidermal necrolysis
  • Pronounced photosensitivity

Precautions & Warnings

  • When using Myconail, consider the following precautions to ensure safe and effective treatment.
  • Apply to intact skin only: avoid broken or inflamed areas.
  • Avoid ocular contact: keep product away from eyes.
  • Do not use on mucous membranes: refrain from applying to mouth or genital mucosa.
  • Discontinue if severe irritation occurs: seek medical advice.
  • Use only as directed by healthcare professional: follow prescribed regimen.
  • Store at room temperature: keep in original container, protect from moisture and light.

Avoid Interactions

Ciclopirox topical has limited systemic interactions, but certain co‑administered agents may affect tolerability or efficacy.

Major Interactions (Avoid)

  • Other topical antifungal agents (e.g., azole creams): may increase risk of skin irritation.
  • Topical corticosteroids applied simultaneously: can mask infection signs and reduce antifungal effectiveness.

Moderate Interactions (Monitor Closely)

  • Systemic antifungal therapy (e.g., oral itraconazole): monitor for overlapping toxicity.
  • Skin care products containing alcohol or harsh surfactants: may enhance local irritation.
  • Phototoxic agents (e.g., psoralen): increase risk of photosensitivity when combined with ciclopirox.

Frequently Asked Questions

Myconail contains ciclopirox and is indicated for the topical treatment of fungal skin infections such as dermatophytosis (including tinea corporis, pedis and cruris), cutaneous candidiasis, and onychomycosis. It works by eliminating the causative fungi, helping to clear lesions, reduce symptoms and prevent recurrence when used as directed by a healthcare professional.

Ciclopirox acts by chelating polyvalent metal ions like iron and aluminum, which are essential cofactors for fungal enzymes. This chelation blocks metal‑dependent enzymatic pathways involved in cell membrane synthesis and metabolic processes, leading to disruption of fungal cell integrity and ultimately causing fungal cell death.

The dosage of Myconail is determined by the prescribing clinician based on the type and severity of the infection, the patient’s age, and the area of skin involved. The prescriber will provide specific instructions on how much product to apply, the frequency of application, and the duration of therapy.

Safety data for ciclopirox topical use in pregnancy and lactation are limited. Healthcare providers should weigh the potential benefits against any possible risks. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss the use of Myconail with their doctor before starting treatment.

To order Myconail, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams across international markets. After the request, the sales team will verify trade or institutional credentials, then provide pricing, availability, shipping details (including any cold‑chain requirements) and assist with import documentation.

Myconail (ciclopirox) belongs to a different class than azole or allylamine topical agents. While azoles inhibit ergosterol synthesis, ciclopirox chelates metal ions, offering a distinct mechanism that can be effective against strains resistant to azoles. Clinical choice depends on infection type, resistance patterns, patient tolerance and physician preference.

Myconail should be stored at room temperature, ideally below 25 °C, in its original packaging to protect it from moisture and direct light. Keep the container tightly closed when not in use. Do not freeze the product, and keep it out of reach of children.

Myconail is applied topically to the affected skin area. The prescriber will advise the amount to use, typically a thin layer, and the frequency—often once or twice daily—depending on the infection. The medication should be spread gently and allowed to dry before covering the area with clothing or bandages.

Although uncommon, serious adverse reactions can include severe allergic responses such as angioedema, anaphylaxis, or widespread skin eruptions like Stevens‑Johnson syndrome and toxic epidermal necrolysis. Patients should discontinue use and seek immediate medical attention if they notice signs of a severe reaction, such as extensive rash, swelling, or difficulty breathing.

Myconail should not be used by individuals with a known hypersensitivity to ciclopirox or any of the product’s excipients. It is also contraindicated on broken, severely inflamed, or mucosal skin surfaces. Patients with a history of severe skin reactions to topical medications should consult their healthcare provider before using Myconail.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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