Mycophenolate Mofetil 500mg Injection (Mycophenolate Mofetil Vials) 500mg

Mycophenolate Mofetil 500mg Injection is an intravenous immunosuppressant medication supplied as a lyophilized powder for solution in vials. It belongs to the class of inosine monophosphate dehydrogenase (IMPDH) inhibitors. This prescription drug is designed to selectively inhibit the proliferation of T and B lymphocytes, helping to prevent the body from rejecting transplanted organs.

Strength

500mg

Pack Size

Storage

Ambient

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Indications & Clinical Uses

This medication is indicated for the prophylaxis of organ rejection in patients receiving allogeneic renal, cardiac, or hepatic transplants. It is administered intravenously, typically in patients who are temporarily unable to take oral medication, as part of a comprehensive immunosuppressive regimen.

Side Effects

Common side effects include diarrhea, leukopenia, sepsis, vomiting, and an increased risk of infections. Serious adverse effects can include severe neutropenia, gastrointestinal bleeding, and an elevated risk of developing lymphomas or other malignancies due to systemic immunosuppression.

Precautions & Warnings

Mycophenolate Mofetil is associated with an increased risk of first-trimester pregnancy loss and congenital malformations (Pregnancy Category D); effective contraception is required. Patients should undergo regular complete blood count monitoring to detect potential neutropenia. It should be avoided in patients with known hypersensitivity to the drug or to mycophenolic acid.

Avoid Interactions

Concomitant use with antacids, proton pump inhibitors, or cholestyramine can significantly decrease mycophenolate absorption and efficacy. Co-administration with acyclovir or ganciclovir may increase the plasma concentrations of both drugs. Additionally, live vaccines should be avoided during treatment due to reduced vaccine efficacy and safety concerns.

Frequently Asked Questions

Mycophenolate Mofetil 500mg Injection is a prescription immunosuppressant used to prevent organ rejection in patients who have received allogeneic kidney, heart, or liver transplants.

This medication is administered intravenously as an infusion by a healthcare professional. It is prepared from a lyophilized powder vial and is typically used when oral administration is temporarily not feasible.

Key risks include an increased susceptibility to serious infections, a higher risk of developing lymphomas or skin cancers, and severe fetal harm or pregnancy loss if used during pregnancy.

No, Mycophenolate Mofetil is contraindicated during pregnancy unless there are no suitable alternative treatments, as it carries a high risk of miscarriage and congenital malformations.

It belongs to the class of inosine monophosphate dehydrogenase (IMPDH) inhibitors, which work by selectively blocking the pathway needed for T and B lymphocyte proliferation.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated: 17 Jun 2026

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