Product image of Mycophenolatmofetil Accord (Mycophenolate Mofetil) supplied by GNH India

Mycophenolatmofetil Accord

Active Ingredient:
Mycophenolate Mofetil
Origin:
EU

Mycophenolatmofetil Accord (Mycophenolate Mofetil)

Mycophenolate Mofetil, the active ingredient in Mycophenolatmofetil Accord, is an immunosuppressant (antimetabolite) presented as an intravenous formulation for use in transplant and autoimmune disease management. It works by inhibiting lymphocyte proliferation, helping to prevent organ rejection and control severe autoimmune activity.

GNH India supplies Mycophenolatmofetil Accord as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres and pharmacies worldwide.

Manufacturer / TM Owner

Accord Healthcare B.V.

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Mycophenolate Mofetil is employed in conditions where immune suppression is required, particularly in transplant and autoimmune pathways.

  • Organ transplant rejection: helps prevent acute and chronic rejection by suppressing T‑cell activation.
  • Lupus nephritis: reduces renal inflammation and proteinuria in patients with systemic lupus erythematosus.
  • Other autoimmune diseases (e.g., vasculitis): controls disease activity by limiting lymphocyte proliferation.

How It Works

  • Mycophenolate Mofetil selectively inhibits inosine monophosphate dehydrogenase (IMPDH), the key enzyme for de novo guanosine nucleotide synthesis in lymphocytes. This blockade reduces guanosine triphosphate pools, impairing DNA synthesis and proliferation of B and T cells, thereby dampening the adaptive immune response without markedly affecting other cell types.

Side Effects

Adverse reactions may vary in frequency and severity.

Common Side Effects

  • Nausea: mild to moderate gastrointestinal upset.
  • Diarrhea: watery stools, sometimes leading to dehydration.
  • Headache: transient cranial discomfort.
  • Hypertension: elevated blood pressure readings.
  • Infections: increased susceptibility to bacterial, viral, or fungal infections.
  • Anemia: reduced red blood cell count causing fatigue.

Serious or Rare Side Effects

  • Leukopenia: marked decrease in white blood cells, raising infection risk.
  • Severe infection: opportunistic infections such as CMV or PCP.
  • Malignancy: increased long‑term risk of lymphoproliferative disorders.
  • Hepatic dysfunction: elevated liver enzymes or hepatitis.
  • Pulmonary toxicity: interstitial lung disease or pneumonitis.
  • Gastrointestinal perforation: rare but life‑threatening bowel injury.

Precautions & Warnings

Mycophenolate Mofetil requires careful monitoring and patient education.

  • Monitor blood counts: perform regular CBC to detect leukopenia or anemia.
  • Assess renal function: adjust therapy if creatinine clearance declines.
  • Pregnancy safety: avoid use in pregnancy unless benefits outweigh risks; drug is category D.
  • Infection vigilance: screen for latent infections and treat promptly.
  • Hepatic monitoring: check liver enzymes periodically.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Mycophenolate Mofetil can interact with several agents, altering efficacy or safety.

Major Interactions (Avoid)

  • Azathiidine: additive bone‑marrow suppression may cause severe cytopenias.
  • Live vaccines: increased risk of vaccine‑derived infection; avoid concurrent use.
  • Strong CYP3A4 inducers (e.g., rifampin): markedly reduce mycophenolate exposure.

Moderate Interactions (Monitor Closely)

  • Tacrolimus or cyclosporine: combined nephrotoxicity; monitor renal parameters.
  • Warfarin: potential alteration of INR; check coagulation status regularly.
  • ACE inhibitors or ARBs: may increase risk of hyperkalemia; monitor electrolytes.

Frequently Asked Questions

Mycophenolatmofetil Accord contains mycophenolate mofetil, which is used to prevent organ transplant rejection and to treat certain autoimmune diseases such as lupus nephritis. It works by suppressing the immune system, reducing the risk of the body attacking a transplanted organ or causing autoimmune inflammation.

Mycophenolate mofetil selectively inhibits the enzyme inosine monophosphate dehydrogenase (IMPDH). This enzyme is essential for the synthesis of guanosine nucleotides in lymphocytes. By blocking this pathway, the drug reduces the proliferation of B and T cells, thereby dampening the immune response that can lead to organ rejection or autoimmune damage.

The dosage of Mycophenolatmofetil Accord is determined by the prescribing clinician based on the patient’s condition, weight, renal function, and other individual factors. Healthcare professionals adjust the dose to achieve the desired immunosuppressive effect while minimizing adverse reactions.

Mycophenolate mofetil is classified as pregnancy category D, indicating evidence of risk to the fetus. It should be avoided during pregnancy unless the potential benefit justifies the risk. Breastfeeding is also not recommended because the drug can be excreted in milk and may affect the infant.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams worldwide. After submission, the sales team will verify trade or institutional credentials and respond with pricing, availability, shipping details (including cold‑chain handling if needed), and any required import documentation.

Compared with calcineurin inhibitors such as tacrolimus or cyclosporine, mycophenolate mofetil offers a different mechanism—targeting nucleotide synthesis rather than calcineurin signaling. It is often used in combination regimens to provide synergistic immunosuppression while allowing lower doses of each agent, potentially reducing individual drug toxicity.

The product should be stored refrigerated at 2‑8 °C. Keep the vial in its original packaging, protect it from light, and avoid freezing or shaking. If the solution is prepared for immediate use, it should be administered promptly and any unused portion discarded according to local regulations.

Mycophenolatmofetil Accord is supplied as an intravenous solution. It is administered by a qualified healthcare professional through a controlled IV infusion, following the prescribing information for infusion rate and monitoring. The exact administration schedule is set by the treating physician.

Serious risks include severe infections due to immunosuppression, leukopenia or other blood dyscrasias, potential development of malignancies, hepatic dysfunction, and rare pulmonary toxicity. Patients should be monitored regularly for signs of infection, blood count changes, liver enzyme elevations, and respiratory symptoms.

Mycophenolatmofetil Accord is contraindicated in patients with known hypersensitivity to mycophenolate mofetil or any component of the formulation. It should also be avoided in pregnant women unless absolutely necessary, and in individuals with uncontrolled infections or severe hepatic impairment without careful risk assessment.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.