Product image of Mycophenolatmofetil Biomo (Mycophenolate Mofetil) supplied by GNH India

Mycophenolatmofetil Biomo

Active Ingredient:
Mycophenolate Mofetil
Origin:
EU

Mycophenolatmofetil Biomo (Mycophenolate Mofetil)

Mycophenolate Mofetil, the active ingredient in Mycophenolatmofetil Biomo, is an immunosuppressant presented as an oral formulation for oral use. It is employed to prevent organ transplant rejection and to treat autoimmune kidney disease such as lupus nephritis in adult patients under specialist supervision and careful monitoring.

GNH India supplies Mycophenolatmofetil Biomo as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, pharmacies and clinics worldwide, ensuring reliable logistics, regulatory support, timely delivery to all regions and adherence to local import requirements.

Manufacturer / TM Owner

Biomo Pharma Gmbh

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Indications & Clinical Uses

Mycophenolate Mofetil is used in immunosuppressive regimens to control immune‑mediated rejection and autoimmunity.

  • Organ transplant rejection prevention: reduces the incidence of acute and chronic graft rejection.
  • Lupus nephritis: improves renal function and slows disease progression in systemic lupus erythematosus.
  • Other autoimmune disorders (e.g., vasculitis): suppresses abnormal immune activity to achieve disease control.

How It Works

  • Mycophenolate Mofetil is a selective, reversible inhibitor of inosine monophosphate dehydrogenase (IMPDH), the key enzyme in de novo guanosine nucleotide synthesis. By blocking IMPDH, the drug depletes guanosine triphosphate pools, which preferentially impairs proliferation of T‑ and B‑lymphocytes that rely on this pathway, thereby dampening cellular and humoral immune responses.

Side Effects

Mycophenolate Mofetil may cause a range of adverse reactions, from mild to serious.

Common Side Effects

  • Nausea
  • Diarrhea
  • Vomiting
  • Headache

Serious or Rare Side Effects

  • Leukopenia or neutropenia
  • Severe opportunistic infections (e.g., Pneumocystis jirovecii pneumonia)
  • Hepatic dysfunction (elevated transaminases, hepatitis)

Precautions & Warnings

When prescribing Mycophenolate Mofetil, clinicians should observe several safety measures.

  • Monitor blood counts: perform regular CBC to detect leukopenia or anemia.
  • Assess renal function: dose may need adjustment in impaired kidneys.
  • Avoid in pregnancy: teratogenic risk; contraindicated.
  • Use effective contraception: due to Category X classification.
  • Vaccination: avoid live vaccines during therapy.
  • Store at below 25°C: keep in the original pack, protect from moisture.

Avoid Interactions

Mycophenolate Mofetil has notable drug interactions that require attention.

Major Interactions (Avoid)

  • Azathioprine: additive bone marrow suppression.
  • Live vaccines: increased risk of infection.
  • Ritonavir/Protease inhibitors: markedly increase mycophenolate exposure.

Moderate Interactions (Monitor Closely)

  • Antacids containing aluminum or magnesium: may reduce absorption.
  • CYP3A4 inhibitors (e.g., ketoconazole): increase plasma levels.
  • CYP3A4 inducers (e.g., rifampin): decrease plasma levels.

Frequently Asked Questions

Mycophenolatmofetil Biomo contains mycophenolate mofetil, an immunosuppressive agent used primarily to prevent rejection after organ transplantation and to treat autoimmune kidney disease such as lupus nephritis. It may also be employed in other severe autoimmune conditions under specialist guidance.

Mycophenolate Mofetil inhibits the enzyme inosine monophosphate dehydrogenase (IMPDH), which is essential for de novo synthesis of guanosine nucleotides. Lymphocytes rely heavily on this pathway, so inhibition reduces their proliferation and dampens both cellular and humoral immune responses, helping to prevent graft rejection and control autoimmunity.

The prescribed dose of Mycophenolatmofetil Biomo is set by the treating physician based on the specific indication, patient weight, renal and hepatic function, and any concomitant medications. Dosing regimens vary between transplant prophylaxis and autoimmune disease management, and adjustments may be required over time.

Mycophenolate Mofetil is classified as Pregnancy Category X because it is teratogenic and can cause fetal malformations. It is contraindicated during pregnancy and should be stopped well before conception. Breastfeeding is also not recommended, as the drug is excreted in milk and may harm the infant.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain needs) and the necessary import documentation.

Compared with azathioprine, another antimetabolite, mycophenolate offers more selective inhibition of lymphocyte proliferation and generally a lower incidence of certain toxicities, but both can cause bone‑marrow suppression. Compared with calcineurin inhibitors (e.g., cyclosporine), mycophenolate has a different side‑effect profile, lacking nephrotoxicity but requiring monitoring for gastrointestinal and hematologic effects.

Mycophenolatmofetil Biomo should be stored at temperatures below 25 °C, in its original packaging, and protected from moisture and direct sunlight. Keep the product out of reach of children and avoid exposing it to excessive heat or humidity to maintain potency.

The medication is taken orally, usually as whole tablets or capsules. It can be taken with or without food, but consistent intake with respect to meals helps maintain stable absorption. Patients should swallow the dose whole and not crush or chew the tablets unless specifically instructed by a healthcare professional.

Serious risks include bone‑marrow suppression leading to leukopenia or anemia, severe opportunistic infections such as Pneumocystis jirovecii pneumonia, hepatic dysfunction, and teratogenic effects if pregnancy occurs. Patients should report signs of infection, unusual bruising, jaundice, or any pregnancy‑related concerns immediately to their clinician.

Mycophenolatmofetil Biomo is contraindicated in pregnant women, individuals with known hypersensitivity to mycophenolate or its excipients, patients with uncontrolled active infections, and those with severe renal impairment unless dose‑adjusted under specialist supervision. Caution is also advised for patients with significant hepatic disease.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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