Product image of Mycoril (Clotrimazole) supplied by GNH India

Mycoril

Active Ingredient:
Clotrimazole
Origin:
EU

Mycoril (Clotrimazole)

Clotrimazole, the active ingredient in Mycoril, is an imidazole antifungal presented as a topical formulation for skin use. It treats superficial fungal infections such as ringworm, athlete's foot and cutaneous candidiasis in adults and children when applied to the affected area.
GNH India supplies Mycoril as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Remedica Ltd

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Indications & Clinical Uses

Clotrimazole is used to treat fungal skin infections by targeting the dermatophyte and yeast organisms that cause them.

  • Dermatophytosis (ringworm): eliminates the fungal infection of skin, hair and nails.
  • Tinea corporis: clears body ringworm lesions and relieves associated itching.
  • Tinea pedis: resolves athlete's foot symptoms and eradicates the causative fungus.
  • Cutaneous candidiasis: treats yeast infections of the skin, reducing redness and discomfort.

How It Works

  • Clotrimazole inhibits the fungal cytochrome P450 enzyme lanosterol 14α‑demethylase, blocking the conversion of lanosterol to ergosterol. This disruption impairs ergosterol synthesis, a key component of fungal cell membranes, leading to increased membrane permeability and ultimately fungal cell death.

Side Effects

Topical clotrimazole may cause local skin reactions, most of which are mild and transient.

Common Side Effects

  • Burning sensation at the application site
  • Itching or mild irritation
  • Redness of the skin
  • Dryness or peeling
  • Mild rash or erythema
  • Stinging feeling

Serious or Rare Side Effects

  • Severe allergic reaction (anaphylaxis)
  • Contact dermatitis with swelling
  • Blistering or severe skin irritation
  • Extensive rash covering large areas
  • Systemic absorption leading to liver enzyme changes (rare)
  • Persistent ulceration or necrosis of skin.

Precautions & Warnings

When using Mycoril, follow these safety measures to minimize risks.

  • Avoid application on broken or inflamed skin: limit use to intact epidermis.
  • Do not apply near eyes, mouth or mucous membranes: risk of irritation.
  • Use only external application: not for internal or systemic use.
  • Keep out of reach of children: prevent accidental ingestion.
  • Discontinue use and seek medical advice if severe irritation occurs.
  • Store at room temperature: keep in the original container, protect from moisture and light.

Avoid Interactions

Clotrimazole may interact with other topical agents or systemic antifungals.

Major Interactions (Avoid)

  • Concurrent use with other topical antifungal creams containing azoles: may increase local irritation.
  • Simultaneous systemic azole therapy (e.g., fluconazole): can raise systemic clotrimazole levels, increasing risk of adverse effects.

Moderate Interactions (Monitor Closely)

  • Co‑application with topical corticosteroids: may reduce antifungal efficacy.
  • Use under occlusive dressings: enhances absorption, monitor for skin reactions.
  • Combination with other skin irritants (e.g., harsh soaps): may exacerbate local irritation.

Frequently Asked Questions

Mycoril is a topical antifungal medication indicated for superficial fungal infections such as dermatophytosis (ringworm), tinea corporis (body ringworm), tinea pedis (athlete's foot) and cutaneous candidiasis (skin yeast infection). It is applied directly to the affected skin area to eliminate the causative fungi.

Clotrimazole, the active ingredient in Mycoril, blocks the fungal enzyme lanosterol 14α‑demethylase, which is essential for ergosterol synthesis. By preventing ergosterol formation, the drug disrupts the fungal cell membrane, increasing its permeability and leading to fungal cell death.

The dosing regimen for Mycoril is determined by the prescribing healthcare professional based on the infection type, severity, patient age and skin condition. Typically, a thin layer is applied to the affected area once or twice daily for the period recommended by the prescriber.

The safety of topical clotrimazole during pregnancy and lactation has not been definitively established. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their healthcare provider before using Mycoril.

To place an order, submit an enquiry on the Mycoril product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Mycoril (clotrimazole) belongs to the imidazole class, offering broad‑spectrum activity against dermatophytes and yeasts. Compared with allylamine agents such as terbinafine, clotrimazole is generally well‑tolerated and available over the counter, though it may require longer treatment durations for some infections.

Mycoril should be stored at room temperature, below 25 °C. Keep the product in its original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed when not in use.

Mycoril is applied topically to clean, dry skin. A thin layer should be spread over the affected area and surrounding skin, usually once or twice daily as directed by a healthcare professional. Hands should be washed after application.

Serious risks, though rare, include severe allergic reactions such as anaphylaxis, extensive contact dermatitis, blistering, or systemic effects from significant absorption. If any signs of a serious reaction appear, discontinue use and seek immediate medical attention.

Mycoril should not be used on broken, inflamed or infected skin, nor on mucous membranes, eyes, or genital areas. Individuals with known hypersensitivity to clotrimazole or any component of the formulation should avoid using the product.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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