Product image of Mycostatin (Ready Mixed) (Nystatin) supplied by GNH India

Mycostatin (Ready Mixed)

Active Ingredient:
Nystatin
Origin:
EU

Mycostatin (Ready Mixed) (Nystatin)

Nystatin, the active ingredient in Mycostatin (Ready Mixed), is a polyene antifungal presented as a ready mixed oral suspension for oral use. It treats oral, esophageal and intestinal candidiasis in patients with fungal infections.

GNH India supplies Mycostatin (Ready Mixed) as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Substipharm

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Indications & Clinical Uses

  • Nystatin is used to treat fungal infections of the mucous membranes and gastrointestinal tract.
  • Oral candidiasis (thrush): reduces fungal load and resolves oral lesions.
  • Esophageal candidiasis: eradicates Candida species and promotes healing of esophageal lesions.
  • Intestinal candidiasis: controls overgrowth of Candida in the gut and alleviates related gastrointestinal symptoms.

How It Works

  • Nystatin binds to ergosterol, a sterol component of fungal cell membranes, forming pores that increase membrane permeability. The resulting leakage of intracellular ions and macromolecules disrupts cellular homeostasis, leading to fungal cell death. This polyene activity is selective for fungi because mammalian cells contain cholesterol rather than ergosterol.

Side Effects

Nystatin may cause adverse reactions, most of which are mild and localized to the gastrointestinal tract.

Common Side Effects

  • Nausea: mild stomach discomfort or queasiness.
  • Vomiting: occasional expulsion of stomach contents.
  • Diarrhea: loose stools occurring during treatment.
  • Abdominal pain: cramping or discomfort in the stomach area.
  • Taste alteration: temporary change in taste perception.

Serious or Rare Side Effects

  • Allergic reaction: rash, itching, swelling, or hives.
  • Anaphylaxis: life‑threatening systemic allergic response (very rare).

Precautions & Warnings

  • When using Mycostatin (Ready Mixed), consider the following precautions.
  • Pregnancy: safety not established; use only if clearly needed.
  • Breastfeeding: unknown; weigh benefits against potential risks.
  • Renal impairment: monitor as drug is excreted unchanged.
  • Concomitant antibiotics: may alter gut flora, monitor for overgrowth.
  • Store at below 25°C: keep in the original container, protect from moisture and light.

Avoid Interactions

Mycostatin (Ready Mixed) can interact with other medicines; review the following.

Major Interactions (Avoid)

  • Broad-spectrum antibiotics: may disrupt normal flora and increase risk of fungal overgrowth.
  • Antacids containing aluminum or magnesium: can reduce suspension absorption.

Moderate Interactions (Monitor Closely)

  • Oral contraceptives: theoretical reduction in efficacy, monitor menstrual changes.
  • Immunosuppressants: increased risk of systemic fungal infection, monitor patient status.
  • Probiotics: may affect gut microbiome balance, observe for symptoms.

Frequently Asked Questions

Mycostatin (Ready Mixed) is indicated for oral candidiasis (thrush), esophageal candidiasis, and intestinal candidiasis. In each case the nystatin suspension works locally to eliminate Candida species, relieve symptoms and promote healing of the affected mucosal surfaces.

Nystatin binds selectively to ergosterol, a sterol unique to fungal cell membranes. This binding creates pores that increase membrane permeability, causing essential intracellular components to leak out. The loss of cellular homeostasis leads to rapid fungal cell death, while human cells are largely unaffected because they contain cholesterol instead of ergosterol.

The exact dose of Mycostatin (Ready Mixed) is set by the prescribing healthcare professional. Dosage depends on factors such as the type and severity of the candidiasis, the patient’s age, weight, renal function and overall clinical condition. Patients should follow the prescriber’s instructions and use the supplied measuring device.

Safety of nystatin in pregnancy and lactation has not been definitively established. It is classified as pregnancy category unknown. Use is recommended only when the potential benefit justifies any possible risk to the fetus or infant, and the decision should be made in consultation with a qualified healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity of Mycostatin (Ready Mixed). GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Mycostatin (nystatin) is a polyene antifungal that acts locally in the gastrointestinal tract and has minimal systemic absorption, making it ideal for mucosal candidiasis. Fluconazole is an azole that is absorbed systemically and is used for deeper or disseminated infections. Nystatin’s spectrum is limited to Candida species, while fluconazole covers a broader range of fungi but may have more drug‑interaction potential.

Store Mycostatin (Ready Mixed) at temperatures below 25 °C. Keep the suspension in its original container, protect it from moisture and direct light, and ensure the cap is tightly closed. Do not freeze the product, and discard any suspension that appears discoloured or has an off‑odor.

Mycostatin (Ready Mixed) is an oral suspension. Shake the bottle well before each use, measure the prescribed dose with a calibrated oral syringe or measuring spoon, and swallow the dose directly or mix it with a small amount of food or drink if needed. It may be taken with or without meals, unless otherwise directed by the prescriber.

The most serious risks include allergic reactions such as rash, swelling, itching, or hives, and in rare cases anaphylaxis, which requires immediate medical attention. Severe gastrointestinal upset, such as persistent vomiting or bloody diarrhea, should also be reported promptly. Patients should seek urgent care if any signs of a severe reaction develop.

Mycostatin (Ready Mixed) should not be used by individuals with a known hypersensitivity to nystatin or any other component of the formulation. Patients with severe renal impairment should use it only under medical supervision, and it is generally avoided in pregnant or breastfeeding women unless the potential benefit outweighs the risk.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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