Product image of Mydriacyl (Tropicamide) supplied by GNH India

Mydriacyl

Active Ingredient:
Tropicamide
Origin:
EU

Mydriacyl (Tropicamide)

Tropicamide, the active ingredient in Mydriacyl, is an anticholinergic (muscarinic antagonist) presented as a 0.5% w/v ophthalmic solution for ocular (topical) use. It produces reversible pupil dilation and cycloplegia, facilitating detailed eye examinations, refraction assessments, and intra‑ocular surgical procedures in patients of all ages.

GNH India supplies Mydriacyl as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, providing reliable sourcing, regulatory support, and consistent product quality for ophthalmic care. Our global distribution network ensures timely delivery across Europe, Asia, Africa and the Americas.

Manufacturer / TM Owner

Alcon Eye Care Uk Limited

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Indications & Clinical Uses

Mydriacyl (tropicamide) acts on the muscarinic receptors of the eye to produce controlled dilation and cycloplegia.

  • Eye examination: induces mydriasis for detailed retinal evaluation.
  • Refraction: provides cycloplegia to allow accurate measurement of refractive error.
  • Intraocular surgery: facilitates pupil dilation and relaxation of the ciliary muscle during procedures.

How It Works

  • Tropicamide reversibly antagonizes muscarinic acetylcholine receptors in the iris sphincter and ciliary body. By blocking these receptors, it prevents parasympathetic-mediated constriction of the pupil and accommodation, resulting in rapid dilation (mydriasis) and loss of focusing ability (cycloplegia) that are useful for diagnostic and surgical ophthalmic procedures.

Side Effects

Adverse reactions may occur following ocular administration of Mydriacyl.

Common Side Effects

  • Transient stinging or burning sensation at the instillation site.
  • Mild blurred vision lasting several hours.
  • Temporary photophobia due to enlarged pupil.
  • Slight increase in intraocular pressure in susceptible individuals.

Serious or Rare Side Effects

  • Acute angle‑closure glaucoma.
  • Severe allergic reaction such as eyelid edema, rash, or urticaria.
  • Systemic anticholinergic toxicity (rare) presenting with dry mouth, tachycardia, or confusion.

Precautions & Warnings

Before using Mydriacyl, consider the following safety measures.

  • Assess intraocular pressure: avoid in patients with narrow‑angle glaucoma.
  • Avoid concurrent use with other mydriatics: may cause excessive dilation.
  • Use with caution in children: increased sensitivity to anticholinergic effects.
  • Do not apply to infected ocular surface: risk of systemic absorption.
  • Pregnancy and lactation: safety not established; weigh benefits against potential risks.
  • Store at room temperature: keep in original container, protect from light and moisture.

Avoid Interactions

Mydriacyl may interact with other ophthalmic or systemic agents.

Major Interactions (Avoid)

  • Other anticholinergic agents: additive systemic anticholinergic effects.
  • Miotic agents (e.g., pilocarpine): antagonistic effect reducing efficacy.

Moderate Interactions (Monitor Closely)

  • Topical anesthetics: may increase ocular absorption of tropicamide.
  • Beta‑blocker eye drops: monitor intraocular pressure closely.
  • Systemic antihistamines: may enhance mydriasis and photophobia.

Frequently Asked Questions

Mydriacyl contains tropicamide, a mydriatic and cycloplegic agent used to dilate the pupil and temporarily paralyze the eye's focusing ability. It is employed during comprehensive eye examinations, refraction testing, and intra‑ocular surgical procedures to improve visual access and measurement accuracy.

Tropicamide blocks muscarinic acetylcholine receptors in the iris sphincter and ciliary body. This inhibition prevents parasympathetic‑mediated constriction of the pupil and accommodation, leading to rapid pupil dilation (mydriasis) and loss of focusing power (cycloplegia) that facilitate ocular assessment and surgery.

The prescribed dose of Mydriacyl is determined by the treating eye‑care professional. Typically, one or two drops are instilled in the conjunctival sac of the target eye(s) as directed, with the interval and frequency set according to the specific clinical need.

Safety data for tropicamide in pregnancy and lactation are limited, and the product is classified as pregnancy category unknown. Use only if the potential benefit justifies any possible risk to the fetus or infant, and discuss with a healthcare provider before treatment.

To request Mydriacyl, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Mydriacyl (tropicamide) provides a relatively rapid onset and short duration of action compared with longer‑acting agents such as phenylephrine or cyclopentolate. This makes it suitable for routine examinations where brief dilation is desired, while other agents may be preferred for prolonged surgical procedures.

Mydriacyl should be stored at room temperature, below 25 °C, in its original container. Protect the bottle from direct light and moisture to maintain stability and potency throughout its shelf life.

Mydriacyl is applied topically to the eye as an ophthalmic solution. The recommended method is to instill the prescribed number of drops into the conjunctival sac of each eye, avoiding contact with the eyelid or lashes, and to observe the patient for the desired dilation effect.

The most serious adverse events include acute angle‑closure glaucoma, severe allergic reactions (e.g., eyelid swelling, rash), and rare systemic anticholinergic toxicity. Patients should be monitored for signs of increased intraocular pressure or hypersensitivity, and treatment should be discontinued if serious reactions occur.

Mydriacyl is contraindicated in individuals with known hypersensitivity to tropicamide or any formulation component, and it should be avoided in patients with narrow‑angle or acute angle‑closure glaucoma unless specifically directed by an ophthalmologist.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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