Product image of Myfortic (Mycophenolic Acid) supplied by GNH India

Myfortic

Active Ingredient:
Mycophenolic Acid
Origin:
EU

Myfortic (Mycophenolic Acid)

Mycophenolic Acid, the active ingredient in Myfortic, is an Antimetabolite presented as a delayed‑release tablet for oral use. It is used to prevent organ rejection in patients who have undergone renal, heart or liver transplantation.
GNH India supplies Myfortic as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres and pharmacies worldwide.

Manufacturer / TM Owner

Novartis Farmacéutica S.A.

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Indications & Clinical Uses

Myfortic is an immunosuppressant that acts on the lymphocyte proliferation pathway to reduce transplant rejection.

  • Renal transplantation: helps prevent organ rejection in kidney transplant recipients.
  • Heart transplantation: reduces the risk of heart graft rejection.
  • Liver transplantation: supports long‑term graft survival by inhibiting immune‑mediated damage.

How It Works

  • Mycophenolic Acid inhibits inosine monophosphate dehydrogenase (IMPDH), the key enzyme for de novo guanosine nucleotide synthesis. This reduction limits the availability of guanosine nucleotides, thereby suppressing the proliferation of T‑ and B‑lymphocytes that drive immune responses against transplanted organs.

Side Effects

Adverse reactions may occur with Myfortic and should be monitored.

Common Side Effects

  • Nausea: mild to moderate stomach upset.
  • Diarrhea: loose stools that may affect hydration.
  • Headache: intermittent pain often relieved with rest.
  • Tremor: fine shaking of hands or limbs.

Serious or Rare Side Effects

  • Infections: increased susceptibility to bacterial, viral or fungal infections.
  • Leukopenia: significant reduction in white blood cell count.
  • Hepatotoxicity: elevated liver enzymes indicating possible liver injury.

Precautions & Warnings

Patients receiving Myfortic should be monitored for safety and efficacy.

  • Monitor blood counts: regular CBC to detect leukopenia or anemia.
  • Monitor liver function: periodic LFTs to identify hepatotoxicity.
  • Avoid live vaccines: risk of uncontrolled infection due to immunosuppression.
  • Use caution in renal impairment: dose adjustment may be required.
  • Pregnancy and breastfeeding: safety not established; discuss risks with a healthcare professional.
  • Store at ambient temperature: keep in the original pack, protect from moisture.

Avoid Interactions

Myfortic can interact with several medicines, altering its effectiveness or safety.

Major Interactions (Avoid)

  • Antacids containing aluminum or magnesium: may reduce absorption of Myfortic.
  • Rifampin: induces metabolism, decreasing drug levels.
  • Cyclosporine: combined use can increase risk of nephrotoxicity.

Moderate Interactions (Monitor Closely)

  • Azathioprine: additive bone‑marrow suppression.
  • NSAIDs: may enhance renal adverse effects.
  • Live vaccines: heightened infection risk when used together.

Frequently Asked Questions

Myfortic is prescribed to prevent rejection of transplanted organs, specifically in patients who have received kidney, heart or liver transplants. By suppressing the immune response, it helps maintain graft function and improves long‑term transplant outcomes.

Mycophenolic Acid blocks the enzyme inosine monophosphate dehydrogenase, which is essential for making guanosine nucleotides. This limits the proliferation of T‑ and B‑lymphocytes, the immune cells responsible for attacking transplanted tissue, thereby reducing the risk of rejection.

The dosage of Myfortic is individualized by the prescribing physician based on the patient’s transplant type, renal function, and other clinical factors. Patients should follow the exact dosing instructions provided by their healthcare professional.

The safety of Myfortic in pregnancy and lactation has not been established. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their transplant team before using this medication.

To request Myfortic, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Myfortic (mycophenolic acid) is an antimetabolite that specifically inhibits lymphocyte proliferation, whereas calcineurin inhibitors such as tacrolimus act on T‑cell activation pathways. Myfortic is often used in combination with other agents to achieve synergistic immunosuppression while offering a different side‑effect profile.

Myfortic should be stored at ambient temperature, below 25 °C, in its original packaging to protect it from moisture and light. Keep the tablets out of reach of children and do not use them after the expiration date.

Myfortic is taken orally as a delayed‑release tablet, usually once or twice daily as directed by the transplant physician. The tablets should be swallowed whole with water and not crushed, chewed, or split.

Serious risks include severe infections due to immune suppression, leukopenia (low white blood cell count), and hepatotoxicity (liver injury). Patients should be monitored regularly for signs of infection, blood count changes, and liver function abnormalities.

Myfortic is contraindicated in patients with known hypersensitivity to mycophenolic acid or any of the tablet’s excipients. It should also be avoided in individuals with uncontrolled severe infections or active malignancy unless specifically directed by a specialist.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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