Product image of Mykronor (Noradrenaline Tartrate) supplied by GNH India

Mykronor

Active Ingredient:
Noradrenaline Tartrate
Origin:
EU

Mykronor (Noradrenaline Tartrate)

Norepinephrine, the active ingredient in Mykronor, is a sympathomimetic presented as an injectable solution for intravenous use. It is employed to raise blood pressure in acute hypotension, septic shock and cardiogenic shock, providing rapid vasoconstriction and cardiac support in critical care settings.

GNH India supplies Mykronor as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide, with distribution across EU and other regulated markets. The product conforms to EU pharmacopeial standards and is manufactured under strict quality controls.

Manufacturer / TM Owner

Laboratoire Aguettant

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

  • Mykronor (norepinephrine) is used in the management of severe hypotensive states and shock syndromes.
  • Acute hypotension: restores systemic vascular resistance to maintain adequate perfusion.
  • Septic shock: counteracts vasodilatory failure to improve mean arterial pressure.
  • Cardiogenic shock: enhances cardiac output and vascular tone to support circulation.

How It Works

  • Norepinephrine acts as an agonist at α1‑adrenergic receptors, producing potent vasoconstriction that raises systemic vascular resistance and arterial pressure. It also stimulates β1‑adrenergic receptors in the heart, increasing contractility and heart rate, which together improve cardiac output and tissue perfusion during shock states.

Side Effects

Mykronor may cause a range of adverse reactions related to its vasopressor activity and catecholamine effects.

Common Side Effects

  • Headache: mild to moderate headache due to rapid blood pressure changes.
  • Tremor: fine muscle tremor, especially in the hands.
  • Nausea: occasional nausea or vomiting.
  • Palpitations: sensation of rapid heartbeat.
  • Peripheral ischemia: reduced blood flow to extremities causing coldness.

Serious or Rare Side Effects

  • Arrhythmias: potentially life‑threatening cardiac rhythm disturbances.
  • Severe hypertension: excessive rise in blood pressure leading to organ damage.
  • Myocardial ischemia: reduced heart‑muscle blood flow causing chest pain.
  • Lactate accumulation: metabolic acidosis in prolonged high‑dose infusion.

Precautions & Warnings

  • When using Mykronor, careful monitoring and specific safety measures are required.
  • Dose titration: adjust infusion rate based on continuous blood pressure monitoring.
  • Cardiac monitoring: observe for arrhythmias and ischemia during therapy.
  • Extravasation risk: avoid infiltration; stop infusion immediately if leakage occurs.
  • Concomitant vasodilators: use with caution as they may counteract effect.
  • Pregnancy and lactation: safety not established; use only if benefit outweighs risk.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Mykronor can interact with several drug classes, requiring attention to avoid adverse outcomes.

Major Interactions (Avoid)

  • Beta‑blockers: may blunt the pressor response and increase risk of severe hypotension.
  • MAO inhibitors: can potentiate catecholamine effects leading to hypertensive crisis.
  • Tricyclic antidepressants: may enhance norepinephrine activity causing excessive vasoconstriction.

Moderate Interactions (Monitor Closely)

  • Vasodilators (e.g., nitroglycerin): may require higher norepinephrine doses.
  • Calcium channel blockers: can affect cardiac contractility, monitor heart function.
  • Diuretics: may alter intravascular volume, influencing response.

Frequently Asked Questions

Mykronor is an intravenous formulation of norepinephrine used in hospital settings to treat acute hypotension, septic shock and cardiogenic shock. By rapidly increasing vascular tone and cardiac output, it helps restore adequate blood pressure and organ perfusion in critically ill patients.

Norepinephrine stimulates α1‑adrenergic receptors on blood vessels, causing vasoconstriction and raising systemic vascular resistance. It also activates β1‑adrenergic receptors in the heart, enhancing contractility and heart rate. The combined effect increases arterial pressure and improves tissue perfusion during shock.

The dose of Mykronor is individualized. A qualified prescriber determines the starting infusion rate and titrates it based on the patient’s blood pressure response and clinical condition. Dosing is adjusted continuously in an intensive‑care environment.

Safety data for norepinephrine in pregnancy and lactation are limited. It should only be used when the potential benefit to the mother outweighs any possible risk to the fetus or infant, and the decision must be made by the treating physician.

To order Mykronor, submit an enquiry on the product page at gnhindia.com indicating the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain where required) and any necessary import documentation.

Mykronor (norepinephrine) is considered a first‑line vasopressor for most shock states because of its balanced α1‑mediated vasoconstriction and β1‑mediated cardiac support. Compared with agents such as phenylephrine (pure α1) or dopamine (dose‑dependent), norepinephrine typically offers more predictable blood‑pressure control with fewer tachyarrhythmic effects.

Mykronor must be stored at 2‑8 °C in a refrigerator, protected from light. Do not freeze or shake the vial. Before use, allow the product to reach room temperature if required, and inspect for particulate matter or discoloration. Follow aseptic technique when preparing the IV infusion.

Mykronor is administered as an intravenous infusion. The solution is diluted in a compatible carrier fluid and delivered via a calibrated infusion pump. Continuous hemodynamic monitoring is essential, and the infusion rate is adjusted to achieve target blood‑pressure goals.

Serious risks include life‑threatening arrhythmias, severe hypertension, myocardial ischemia, and peripheral ischemic injury from excessive vasoconstriction. Prompt recognition of chest pain, abnormal heart rhythms, or sudden spikes in blood pressure is critical, and the infusion should be adjusted or stopped as clinically indicated.

Mykronor is contraindicated in patients with known hypersensitivity to norepinephrine or any of its excipients. Caution is advised in individuals with uncontrolled hypertension, severe peripheral vascular disease, or those receiving MAO inhibitors, as the drug may exacerbate these conditions.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.