Product image of Mylatabi (Eltrombopag) supplied by GNH India

Mylatabi

Active Ingredient:
Eltrombopag
Origin:
EU

Mylatabi (Eltrombopag)

Eltrombopag, the active ingredient in Mylatabi, is a thrombopoietin receptor agonist presented as an oral tablet for oral use. It is indicated for the treatment of chronic immune thrombocytopenia, severe aplastic anemia, and thrombocytopenia associated with chronic hepatitis C in appropriate patient populations.

GNH India supplies Mylatabi as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Tillomed Malta Ltd

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Indications & Clinical Uses

Eltrombopag is used to stimulate platelet production in disorders characterized by thrombocytopenia.

  • Chronic immune thrombocytopenia (ITP): increases platelet counts to reduce bleeding risk.
  • Severe aplastic anemia: supports hematopoiesis by raising platelet levels in patients refractory to other treatments.
  • Thrombocytopenia associated with chronic hepatitis C: improves platelet counts to facilitate antiviral therapy.

How It Works

  • Eltrombopag binds to the thrombopoietin receptor (c-Mpl) on megakaryocyte precursors, acting as an agonist. This activation triggers intracellular signaling pathways that promote megakaryocyte proliferation and differentiation, leading to increased platelet production in the bone marrow and higher circulating platelet counts.

Side Effects

Eltrombopag may cause a range of adverse reactions, which are categorized by frequency and severity.

Common Side Effects

  • Nausea
  • Diarrhea
  • Fatigue
  • Headache
  • Elevated liver enzymes
  • Dyspepsia

Serious or Rare Side Effects

  • Hepatic failure
  • Severe thrombotic events
  • Neutropenia
  • Anaphylactic reactions
  • Retinal pigment epithelium changes

Precautions & Warnings

When prescribing or dispensing Eltrombopag, several safety considerations should be observed.

  • Liver function monitoring: check hepatic enzymes regularly.
  • Thrombotic risk assessment: avoid in patients with active thrombosis.
  • Hypertension control: use caution in uncontrolled high blood pressure.
  • Pregnancy and lactation: risk unknown, weigh benefits against potential hazards.
  • Discontinue if severe adverse reactions occur.
  • Store at room temperature: keep in the original pack, protect from moisture.

Avoid Interactions

Eltrombopag can interact with other medicines, affecting its efficacy or safety.

Major Interactions (Avoid)

  • Strong CYP3A4 inducers (e.g., rifampin): may reduce drug exposure.
  • Antacids containing polyvalent cations: impair absorption.
  • Concurrent use with other thrombopoietin receptor agonists: risk of excessive platelet rise.

Moderate Interactions (Monitor Closely)

  • Moderate CYP3A4 inhibitors (e.g., fluconazole): may increase plasma levels.
  • Warfarin: potential alteration of INR, requiring closer monitoring.

Frequently Asked Questions

Mylatabi, containing eltrombopag, is prescribed for chronic immune thrombocytopenia (ITP), severe aplastic anemia, and thrombocytopenia linked to chronic hepatitis C. In each case, the drug aims to raise platelet counts, helping to prevent bleeding complications and support overall hematologic health.

Eltrombopag acts as an agonist at the thrombopoietin receptor (c-Mpl) on megakaryocyte precursors. By stimulating this receptor, it triggers signaling pathways that promote the growth and maturation of megakaryocytes, the cells responsible for producing platelets, thereby increasing platelet numbers in the bloodstream.

The dosage of Mylatabi is individualized. A qualified prescriber determines the appropriate dose based on the patient’s specific condition, response to therapy, and laboratory values. Patients should follow the prescribing clinician’s instructions and not adjust the dose on their own.

The safety of eltrombopag in pregnancy and lactation has not been established. Because potential risks are unknown, it should only be used if the expected benefit justifies the possible danger to the fetus or infant. Consultation with a healthcare professional is essential.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity of Mylatabi. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Mylatabi (eltrombopag) and other agents such as romiplostim share the same therapeutic goal of increasing platelet production. Eltrombopag is an oral small‑molecule agonist, whereas romiplostim is administered by subcutaneous injection. Choice of therapy often depends on patient preference, route of administration, and specific clinical considerations.

Mylatabi should be stored at room temperature, below 25 °C. Keep the tablets in the original packaging, protect them from moisture and direct sunlight, and ensure they are out of reach of children.

Mylatabi is taken orally, usually with a glass of water. The tablet should be swallowed whole and not crushed or chewed, unless the prescribing information advises otherwise. Dosing times and any food restrictions are determined by the treating physician.

Serious risks include hepatic failure, severe thrombotic events such as deep‑vein thrombosis or arterial clots, and rare cases of severe neutropenia or anaphylaxis. Patients should be monitored regularly for liver function abnormalities and signs of thrombosis, and any concerning symptoms should prompt immediate medical evaluation.

Mylatabi is contraindicated in patients with known hypersensitivity to eltrombopag or any of its excipients, and in individuals with active, uncontrolled thrombosis. Caution is also advised for patients with severe liver impairment, uncontrolled hypertension, or those receiving other thrombopoietin receptor agonists.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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