Product image of Mylatrip (Frovatriptan Succinate Monohydrate) supplied by GNH India

Mylatrip

Active Ingredient:
Frovatriptan Succinate Monohydrate
Origin:
EU

Mylatrip (Frovatriptan Succinate Monohydrate)

Frovatriptan succinate monohydrate, the active ingredient in Mylatrip, is a Triptan presented as an oral tablet for oral use. It is indicated for the acute treatment of migraine attacks in adults.
GNH India supplies Mylatrip as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Generics [uk] Limited

1
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Indications & Clinical Uses

Frovatriptan belongs to the triptan class and is used for acute migraine management.

  • Migraine without aura: provides rapid relief of headache pain and associated symptoms.
  • Migraine with aura: aborts the headache phase after aura has occurred.
  • Acute migraine attacks: reduces severity and duration when taken at the first sign of an attack.

How It Works

  • Frovatriptan succinate monohydrate acts as a selective agonist at serotonin 5‑HT1B and 5‑HT1D receptors located on cranial blood vessels and trigeminal nerve endings. Activation causes vasoconstriction of intracranial arteries and inhibits release of pro‑migraine neuropeptides, thereby terminating the migraine cascade.

Side Effects

Frovatriptan may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects

  • Chest discomfort or tightness
  • Tingling or numbness in the fingers or toes
  • Nausea or abdominal pain
  • Dizziness or light‑headedness
  • Fatigue or drowsiness
  • Dry mouth

Serious or Rare Side Effects

  • Coronary vasospasm or myocardial infarction
  • Serotonin syndrome, especially with serotonergic agents
  • Severe allergic reaction (anaphylaxis, angioedema)
  • Persistent hypertension
  • Severe abdominal pain or gastrointestinal bleeding
  • Vision changes or visual field defects

Precautions & Warnings

Before prescribing frovatriptan, clinicians should evaluate patient‑specific risk factors and contraindications.

  • Cardiovascular assessment: avoid in patients with uncontrolled coronary artery disease.
  • Drug contraindications: do not use with ergot derivatives or other triptans.
  • Dose limitation: do not exceed the recommended maximum number of doses per month.
  • Hepatic impairment: use with caution in patients with liver dysfunction.
  • Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Frovatriptan can interact with several medication classes, requiring careful review.

Major Interactions (Avoid)

  • MAO inhibitors: risk of severe hypertension and serotonin syndrome.
  • Other triptans or ergot alkaloids: additive vasoconstrictive effects.
  • SSRIs, SNRIs, or other serotonergic agents: increased risk of serotonin syndrome.

Moderate Interactions (Monitor Closely)

  • CYP1A2 inhibitors (e.g., fluvoxamine): may increase frovatriptan plasma levels.
  • CYP1A2 inducers (e.g., smoking, carbamazepine): may reduce efficacy.
  • Antihypertensive agents: monitor blood pressure for additive effects.

Frequently Asked Questions

Mylatrip contains frovatriptan succinate monohydrate, a triptan indicated for the acute treatment of migraine attacks in adults. It is taken at the first sign of a migraine to relieve headache pain and associated symptoms such as nausea, photophobia, and phonophobia.

Frovatriptan selectively stimulates serotonin 5‑HT1B and 5‑HT1D receptors on cranial blood vessels and trigeminal nerve endings. This causes vasoconstriction of dilated intracranial arteries and blocks the release of neuropeptides that drive migraine pain, thereby terminating the attack.

The dose of Mylatrip is determined by the prescribing clinician based on the patient’s medical history, severity of migraine, and response to therapy. The prescriber will provide specific dosing instructions and any necessary limits on the number of doses per month.

The safety of frovatriptan in pregnancy and lactation has not been definitively established. It should only be used if the potential benefit justifies the potential risk to the fetus or infant, and this decision must be made by a qualified healthcare professional.

To place an order, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Mylatrip (frovatriptan) has a longer half‑life than many other triptans, which can provide sustained relief and a lower risk of headache recurrence. Its efficacy is comparable, but individual response varies, so clinicians may choose based on patient tolerance, recurrence rates, and drug‑interaction profile.

Mylatrip tablets should be stored at room temperature, below 25 °C, in the original packaging. Protect them from moisture, excessive heat, and direct sunlight to maintain product stability throughout its shelf life.

Mylatrip is taken orally, usually as a single tablet at the onset of migraine symptoms. If the migraine persists after two hours, a second dose may be considered, but the total number of doses per month should not exceed the limit set by the prescriber.

Serious risks include coronary vasospasm or myocardial infarction, especially in patients with underlying cardiovascular disease, and serotonin syndrome when combined with other serotonergic agents. Patients should be educated to seek immediate medical attention for chest pain, severe hypertension, or signs of serotonin excess.

Mylatrip is contraindicated in patients with uncontrolled coronary artery disease, severe hypertension, a history of myocardial infarction, peripheral vascular disease, or in those who have used ergot derivatives or other triptans within the same 24‑hour period. It should also be avoided in patients with known hypersensitivity to frovatriptan.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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