Product image of Myocard (Doxazosin Mesilate) supplied by GNH India

Myocard

Active Ingredient:
Doxazosin Mesilate
Origin:
EU

Myocard (Doxazosin Mesilate)

Doxazosin mesilate, the active ingredient in Myocard, is an alpha-1 adrenergic blocker presented as an oral tablet for oral use. It is indicated for the management of hypertension and for relief of urinary symptoms associated with benign prostatic hyperplasia in adult patients.

GNH India supplies Myocard as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The product complies with EU marketing authorisation standards and is manufactured under GMP conditions. It is distributed through GNH India's global logistics network to ensure timely delivery.

Manufacturer / TM Owner

Teva B.V

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Indications & Clinical Uses

Doxazosin mesilate acts on the alpha‑1 adrenergic pathway to control blood pressure and urinary flow.

  • Hypertension: lowers systemic blood pressure in patients with elevated readings.
  • Essential hypertension: provides long‑term control of primary high blood pressure.
  • Benign prostatic hyperplasia: improves urinary flow and reduces bladder outlet obstruction in men with enlarged prostate.

How It Works

  • Doxazosin mesilate selectively antagonizes alpha‑1 adrenergic receptors on vascular smooth muscle and prostatic tissue. By blocking these receptors, it prevents norepinephrine‑induced vasoconstriction, leading to vasodilation and reduced peripheral vascular resistance, while also relaxing smooth muscle in the prostate and bladder neck to ease urinary obstruction.

Side Effects

Adverse reactions may vary in frequency and severity.

Common Side Effects

  • Dizziness: feeling light‑headed, especially after standing.
  • Headache: mild to moderate pain in the head region.
  • Fatigue: general tiredness or lack of energy.
  • Nasal congestion: blocked or runny nose.
  • Peripheral edema: swelling of the ankles or feet.
  • Nausea: upset stomach or urge to vomit.

Serious or Rare Side Effects

  • Severe hypotension: marked drop in blood pressure that can cause fainting.
  • Syncope: sudden loss of consciousness.
  • Priapism: prolonged, painful erection.
  • Angioedema: swelling of face, lips, tongue or throat.
  • Allergic reaction: rash, itching, or hives.
  • Liver injury: abnormal liver function tests.

Precautions & Warnings

Before initiating therapy, consider the following safety measures.

  • Blood pressure monitoring: check baseline and periodic readings.
  • Hepatic impairment: use with caution in patients with liver disease.
  • Orthostatic hypotension: advise patients to rise slowly from sitting or lying positions.
  • Concomitant antihypertensives: adjust doses to avoid excessive blood pressure lowering.
  • Renal function: assess kidney status, especially in the elderly.
  • Store at room temperature: keep in the original pack, protect from moisture.

Avoid Interactions

Doxazosin may interact with other medicines; awareness of the interaction level is important.

Major Interactions (Avoid)

  • Other alpha‑1 blockers: additive blood pressure reduction.
  • Potent CYP3A4 inhibitors (e.g., ketoconazole): increased plasma concentrations.
  • Phosphodiesterase‑5 inhibitors: risk of severe hypotension.

Moderate Interactions (Monitor Closely)

  • Diuretics: may enhance orthostatic effects.
  • Beta‑blockers: combined effect on heart rate and blood pressure.
  • Other antihypertensives: cumulative lowering of blood pressure.
  • NSAIDs: may blunt antihypertensive response.
  • Lithium: possible increase in lithium levels.

Frequently Asked Questions

Myocard contains doxazosin mesilate and is prescribed for adults with hypertension to lower blood pressure, and for men with benign prostatic hyperplasia to improve urinary flow and reduce bladder outlet obstruction.

Doxazosin mesilate selectively blocks alpha‑1 adrenergic receptors on blood vessels and prostatic smooth muscle, causing vasodilation that reduces peripheral resistance and relaxing the prostate and bladder neck to ease urinary symptoms.

The dose of Myocard is individualized by the prescribing clinician based on the patient’s condition, response, and tolerability. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

The safety of doxazosin mesilate in pregnancy or while nursing is not well established. It should only be used if the potential benefit justifies the potential risk to the fetus or infant, and under medical supervision.

To request Myocard, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Myocard belongs to the alpha‑1 blocker class, which lowers blood pressure by vasodilation. Unlike ACE inhibitors or calcium‑channel blockers, it also relaxes prostatic smooth muscle, offering a dual benefit for patients who have both hypertension and benign prostatic hyperplasia.

Store Myocard at room temperature, below 25 °C, in the original packaging. Keep it away from moisture and direct sunlight to maintain product stability.

Myocard is taken orally, usually once daily, with or without food as directed by the prescriber. Swallow the tablet whole with a glass of water; do not crush or chew unless instructed otherwise.

Serious risks include severe hypotension, syncope, priapism, angioedema, and rare cases of liver injury. Patients should seek immediate medical attention if they experience fainting, prolonged erection, swelling of the face or throat, or signs of liver dysfunction.

Myocard should be avoided in patients with known hypersensitivity to doxazosin or any component of the formulation, and in those with severe hepatic impairment or uncontrolled orthostatic hypotension unless specifically directed by a healthcare professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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