Product image of Myoview (Tetrofosmin) supplied by GNH India

Myoview

Active Ingredient:
Tetrofosmin
Origin:
EU

Myoview (Tetrofosmin)

Tetrofosmin, the active ingredient in Myoview, is a radiopharmaceutical presented as an injectable solution for intravenous use. It is employed for myocardial perfusion imaging in patients undergoing stress and rest studies to assess coronary artery disease and myocardial viability.

GNH India supplies Myoview as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres and clinics worldwide.

Manufacturer / TM Owner

Ge Healthcare

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Indications & Clinical Uses

Myoview (tetrofosmin) is used in cardiac imaging to evaluate myocardial perfusion.

  • Myocardial perfusion imaging (stress and rest): Provides quantitative assessment of blood flow to detect ischemia.
  • Coronary artery disease detection: Helps identify obstructive lesions by comparing perfusion patterns.
  • Myocardial viability assessment: Differentiates viable from scarred myocardium to guide revascularization decisions.

How It Works

  • Tetrofosmin is a lipophilic cation that readily crosses cell membranes and is taken up by viable myocardial cells in proportion to regional blood flow. Once accumulated, its gamma‑emitting properties allow single‑photon emission computed tomography (SPECT) to generate high‑resolution images of myocardial perfusion, reflecting coronary circulation and tissue viability.

Side Effects

Adverse reactions may occur following administration of Myoview.

Common Side Effects

  • Nausea
  • Headache
  • Flushing
  • Injection site pain
  • Dizziness
  • Mild hypotension

Serious or Rare Side Effects

  • Anaphylactic reaction
  • Severe hypotension
  • Life‑threatening arrhythmias
  • Acute respiratory distress
  • Significant chest pain
  • Persistent vomiting

Precautions & Warnings

Myoview requires careful consideration of patient condition and handling.

  • Pregnancy: Safety not established; avoid unless essential.
  • Breastfeeding: Unknown risk; consider discontinuation.
  • Renal impairment: Monitor because clearance may be reduced.
  • Allergy: Assess for hypersensitivity to tetrofosmin or kit components.
  • Radiation exposure: Follow local regulations to limit dose to patient and staff.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Potential drug interactions should be reviewed before Myoview administration.

Major Interactions (Avoid)

  • Concurrent use of other radiopharmaceuticals emitting similar gamma energies may interfere with imaging.
  • Beta‑blockers may alter myocardial blood flow and affect image interpretation.
  • Vasodilators (e.g., nitrates) given shortly before may modify perfusion patterns.

Moderate Interactions (Monitor Closely)

  • Calcium channel blockers may modestly affect tracer uptake.
  • Thyroid disorders may influence radiotracer distribution.

Frequently Asked Questions

Myoview is a radiopharmaceutical used primarily for myocardial perfusion imaging. It helps clinicians evaluate blood flow to the heart muscle during stress and rest conditions, aiding in the detection of coronary artery disease and assessment of myocardial viability.

Tetrofosmin is a lipophilic cation that readily enters viable heart cells in proportion to regional blood flow. Its gamma‑emitting properties enable SPECT cameras to create detailed images of myocardial perfusion, reflecting the functional status of coronary circulation.

The specific dose of Myoview is determined by the prescribing physician based on the imaging protocol, patient weight, and clinical indication. Healthcare professionals calculate the appropriate activity to achieve optimal image quality while adhering to radiation safety guidelines.

Safety data for tetrofosmin in pregnancy and lactation are limited. It is generally avoided unless the diagnostic benefit outweighs potential risks. Women who are pregnant or breastfeeding should discuss alternatives with their healthcare provider.

To order Myoview, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain where required) and necessary import documentation.

Myoview (tetrofosmin) and agents such as technetium‑99m sestamibi share similar imaging principles, but tetrofosmin has a slightly higher myocardial uptake and faster clearance, which can improve image contrast and reduce background activity. Choice of agent depends on local practice, availability, and specific protocol requirements.

Myoview must be stored at 2‑8 °C in a refrigerator, protected from light, and must not be frozen or shaken. Before use, the vial should be inspected for particulate matter and only prepared under aseptic conditions as directed by the manufacturer.

Myoview is administered as an intravenous injection. The radiopharmaceutical is typically injected as a bolus or slow infusion, followed by a waiting period to allow myocardial uptake before SPECT imaging is performed according to the prescribed protocol.

Serious risks include rare anaphylactic reactions, severe hypotension, and life‑threatening arrhythmias. Because Myoview involves ionizing radiation, appropriate radiation safety measures must be observed to protect patients and staff.

Myoview should be avoided in patients with known hypersensitivity to tetrofosmin or any component of the preparation, in those with uncontrolled severe hypotension, and in pregnant or breastfeeding women unless the diagnostic benefit clearly outweighs the potential risk.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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