Product image of Myoview (Tetrofosmin) supplied by GNH India

Myoview

Active Ingredient:
Tetrofosmin
Origin:
EU

Myoview (Tetrofosmin)

Tetrofosmin, the active ingredient in Myoview, is a radiopharmaceutical presented as a solution for injection for intravenous use. It is employed in myocardial perfusion imaging to assess blood flow to the heart muscle, aiding the evaluation of coronary artery disease in adult patients undergoing cardiac stress testing.

GNH India supplies Myoview as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, diagnostic imaging centres and procurement teams worldwide, with adherence to regulatory standards and cold‑chain logistics where required, ensuring product integrity.

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Indications & Clinical Uses

  • Myoview (tetrofosmin) is used in myocardial perfusion imaging to evaluate coronary artery disease.
  • Coronary artery disease: helps visualize perfusion defects to assess severity.
  • Myocardial ischemia: enables detection of stress‑induced perfusion abnormalities.
  • Myocardial viability: assists in distinguishing viable from scarred myocardium for revascularization planning.

How It Works

  • Tetrofosmin is a lipophilic cationic compound that, when labeled with technetium‑99m, readily crosses cell membranes and accumulates in myocardial cells in proportion to regional blood flow. The resulting gamma emission is captured by SPECT cameras, producing images that reflect perfusion patterns and identify areas of reduced blood supply.

Side Effects

Adverse reactions may occur after administration of Myoview.

Common Side Effects

  • Nausea
  • Headache
  • Flushing
  • Injection site pain
  • Dizziness
  • Mild hypotension

Serious or Rare Side Effects

  • Anaphylactic reaction
  • Severe hypotension
  • Cardiac arrhythmia
  • Acute respiratory distress
  • Severe allergic skin reactions

Precautions & Warnings

  • Use of Myoview requires careful consideration of patient-specific factors.
  • Pregnancy: safety not established; avoid unless essential.
  • Breastfeeding: unknown; weigh potential risks.
  • Renal impairment: use with caution; monitor renal function.
  • Allergy: assess for hypersensitivity to technetium‑99m or tetrofosmin.
  • Concurrent cardiac stress agents: follow protocol to avoid interference.
  • Store at ambient temperature: keep in original container, protect from light and moisture.

Avoid Interactions

Myoview may interact with other agents that affect myocardial uptake or radiotracer distribution.

Major Interactions (Avoid)

  • Thyroid hormone therapy: may alter radiotracer uptake.
  • Other radiopharmaceuticals: avoid concurrent administration.

Moderate Interactions (Monitor Closely)

  • Beta‑blockers: may modify heart‑rate response during stress testing.
  • Calcium channel blockers: may influence myocardial blood flow.
  • Vasodilators (e.g., dipyridamole): adjust timing to prevent overlapping effects.

Frequently Asked Questions

Myoview is a radiopharmaceutical used in myocardial perfusion imaging (MPI) to evaluate blood flow to the heart muscle. It helps clinicians detect coronary artery disease, assess myocardial ischemia, and determine tissue viability during cardiac stress testing.

Tetrofosmin is a lipophilic cation that, when labeled with technetium‑99m, is taken up by myocardial cells proportionally to regional blood flow. The emitted gamma photons are captured by SPECT cameras, producing images that reflect perfusion patterns across the heart.

The dose of Myoview is determined by the prescribing physician based on the specific imaging protocol, patient weight, and the type of stress test being performed. Dosage details are provided in the product labeling and should not be altered without medical guidance.

Safety of Myoview in pregnancy and lactation has not been established. It should only be used if the potential diagnostic benefit outweighs the possible risk to the fetus or infant, and after a thorough risk assessment by the healthcare provider.

To order Myoview, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain where applicable) and necessary import documentation.

Myoview (technetium‑99m tetrofosmin) offers rapid myocardial uptake and clear imaging quality comparable to other technetium‑99m agents such as sestamibi. It has a similar safety profile, but differences in biodistribution and imaging timing may influence protocol selection based on institutional preference.

Myoview should be stored at ambient temperature, protected from light and moisture, and kept in its original packaging until use. Do not freeze the solution, and follow local regulations for handling radiopharmaceuticals to maintain stability and safety.

Myoview is administered intravenously as a sterile solution for injection. The radiotracer is injected under controlled conditions, typically shortly before or after a cardiac stress maneuver, and imaging is performed according to the prescribed MPI protocol.

Serious risks, though rare, include severe allergic reactions such as anaphylaxis, marked hypotension, and cardiac arrhythmias. Immediate medical attention is required if any signs of these reactions appear during or after the injection.

Myoview should be avoided in patients with known hypersensitivity to tetrofosmin, technetium‑99m, or any component of the formulation. Caution is also advised for individuals with severe renal impairment or uncontrolled cardiac conditions where stress testing is contraindicated.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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