Product image of Myoview (Tetrofosmin) supplied by GNH India

Myoview

Active Ingredient:
Tetrofosmin
Origin:
EU

Myoview (Tetrofosmin)

Tetrofosmin, the active ingredient in Myoview, is a radiopharmaceutical presented as a 0.5 mg per vial injectable solution for intravenous use. It enables non‑invasive imaging of myocardial blood flow in patients evaluated for coronary artery disease and other cardiac conditions.

GNH India supplies Myoview as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide.

Manufacturer / TM Owner

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Indications & Clinical Uses

  • Tetrofosmin is used in cardiac imaging to evaluate myocardial perfusion and viability.
  • Coronary artery disease: detection of perfusion defects to aid diagnosis.
  • Myocardial viability assessment: identification of viable myocardium after infarction.
  • Stress myocardial perfusion imaging: evaluation of blood flow during pharmacologic or exercise stress.

How It Works

  • Tetrofosmin is a lipophilic cation that, after labeling with technetium‑99m, readily crosses cell membranes and accumulates in myocardial cells in proportion to regional blood flow. The resulting gamma emission is captured by SPECT cameras, producing high‑resolution images of myocardial perfusion for diagnostic interpretation.

Side Effects

Adverse reactions may occur following administration of tetrofosmin.

Common Side Effects

  • Nausea
  • Flushing
  • Headache
  • Dizziness
  • Injection site pain or irritation
  • Mild hypotension

Serious or Rare Side Effects

  • Anaphylactic or severe allergic reaction
  • Severe hypotension or cardiovascular collapse
  • Life‑threatening arrhythmias
  • Acute myocardial infarction
  • Pulmonary edema
  • Death (very rare)

Precautions & Warnings

Careful patient assessment and adherence to handling guidelines are essential when using tetrofosmin.

  • Patient assessment: evaluate cardiac status and renal function before administration.
  • Contraindications: avoid in individuals with known hypersensitivity to tetrofosmin or technetium‑99m compounds.
  • Pregnancy: use only if the diagnostic benefit outweighs potential fetal risk.
  • Breastfeeding: consider temporary cessation of breastfeeding after administration.
  • Drug interactions: avoid simultaneous use of other radiopharmaceuticals that may interfere with imaging.
  • Store at 2‑8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Tetrofosmin may interact with other agents that affect cardiac imaging or hemodynamics.

Major Interactions (Avoid)

  • Concurrent administration of other technetium‑99m radiopharmaceuticals.
  • High‑dose iodinated contrast agents used shortly before imaging.
  • Beta‑blockers that may blunt stress response.

Moderate Interactions (Monitor Closely)

  • Caffeine‑containing products that can affect stress test results.
  • Certain antihypertensive medications.
  • Nitrates and calcium channel blockers.
  • Thyroid hormone preparations.
  • Diuretics that may alter plasma volume.

Frequently Asked Questions

Myoview is a radiopharmaceutical used in single‑photon emission computed tomography (SPECT) to image myocardial perfusion. It helps clinicians detect coronary artery disease, assess myocardial viability after infarction, and evaluate blood flow during stress testing.

Tetrofosmin is a lipophilic cation that, when labeled with technetium‑99m, penetrates heart muscle cells and accumulates proportionally to regional blood flow. The emitted gamma photons are captured by a SPECT camera, producing detailed images of myocardial perfusion.

The specific dose of Myoview is determined by the prescribing physician based on the imaging protocol, patient characteristics, and the amount of technetium‑99m used. The prescriber sets the appropriate activity for each study.

The safety of Myoview in pregnancy and lactation has not been established. It should be used only if the potential diagnostic benefit justifies any potential risk to the fetus or infant, and appropriate precautions should be taken.

To order Myoview, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain where required), and import documentation.

Myoview (tetrofosmin) and agents such as technetium‑99m sestamibi have similar mechanisms, both being lipophilic cations that image myocardial perfusion. Differences may include pharmacokinetic profiles, image quality under certain stress conditions, and specific regulatory approvals, which clinicians consider when selecting an agent.

Myoview should be stored at 2‑8 °C, protected from light, and kept in its original container. Do not freeze or shake the vial. Follow all radiopharmacy handling guidelines to maintain product integrity and radiation safety.

Myoview is administered intravenously as an injectable solution. After reconstitution with technetium‑99m, the prepared dose is injected into a peripheral vein under controlled conditions, typically immediately before the imaging procedure.

Serious risks, although rare, include severe allergic reactions (anaphylaxis), profound hypotension, life‑threatening arrhythmias, acute myocardial infarction, and pulmonary edema. Immediate medical attention is required if any of these events occur.

Myoview should not be administered to patients with known hypersensitivity to tetrofosmin or technetium‑99m compounds, or to those in whom the diagnostic benefit does not outweigh potential risks, such as certain pregnant or lactating women without a clear indication.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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