Product image of Myring (Ethinylestradiol, Etonogestrel) supplied by GNH India

Myring

Active Ingredient:
Ethinylestradiol, Etonogestrel
Origin:
EU

Myring (Ethinylestradiol, Etonogestrel)

Ethinylestradiol/Etonogestrel, the active ingredients in Myring, are a combined estrogen‑progestogen presented as a vaginal ring for vaginal use. It provides hormonal contraception for women of reproductive age, preventing ovulation and pregnancy.
GNH India supplies Myring as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Gynial Gmbh

1
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Indications & Clinical Uses

Myring, a combined estrogen‑progestogen vaginal ring, is used within the hormonal contraceptive pathway to prevent unintended pregnancy.

  • Contraception: Prevents ovulation and pregnancy in women of childbearing age.
  • Family planning: Offers a long‑acting, reversible hormonal method for birth control.
  • Menstrual cycle control: May reduce irregular bleeding and stabilize cycle length.

How It Works

  • Ethinylestradiol and etonogestrel bind to estrogen and progesterone receptors, respectively, suppressing the hypothalamic‑pituitary‑gonadal axis. This inhibition reduces luteinizing hormone (LH) and follicle‑stimulating hormone (FSH) secretion, preventing follicular development and ovulation. The progestogen also thickens cervical mucus and alters the endometrial lining, creating an environment hostile to sperm penetration and implantation.

Side Effects

Myring may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects

  • Nausea: mild to moderate stomach upset.
  • Breast tenderness: discomfort or swelling of the breasts.
  • Headache: occasional throbbing or pressure sensation.
  • Vaginal irritation: redness or itching at the insertion site.
  • Spotting: irregular light bleeding between periods.

Serious or Rare Side Effects

  • Thromboembolic events: deep vein thrombosis or pulmonary embolism.
  • Stroke or myocardial infarction: rare cerebrovascular or cardiac events.
  • Hepatic adenoma: benign liver tumor formation.
  • Severe allergic reaction: rash, swelling, or anaphylaxis.
  • Persistent abdominal pain: may indicate serious intra‑abdominal pathology.

Precautions & Warnings

Before prescribing Myring, clinicians should evaluate patient‑specific risk factors and provide counseling.

  • Assess thrombotic risk: avoid in women with a history of clotting disorders.
  • Screen for hypertension: monitor blood pressure regularly.
  • Evaluate liver function: contraindicated in severe hepatic disease.
  • Avoid smoking: especially in women over 35 years of age.
  • Review concomitant medications: consider potential drug interactions.
  • Store at ambient temperature: keep in the original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Myring can interact with several medicines that alter hormone metabolism or increase clotting risk.

Major Interactions (Avoid)

  • Enzyme‑inducing anticonvulsants (e.g., carbamazepine, phenytoin): may markedly reduce contraceptive efficacy.
  • Rifampin: accelerates hormone clearance, increasing failure risk.
  • Protease inhibitors (e.g., ritonavir): can raise hormone levels and heighten adverse‑event potential.

Moderate Interactions (Monitor Closely)

  • Broad‑spectrum antibiotics (e.g., tetracycline): may slightly diminish effectiveness.
  • St. John’s wort: herbal inducer that can lower hormone concentrations.
  • Azole antifungals (e.g., ketoconazole): may increase hormone exposure, requiring monitoring.

Frequently Asked Questions

Myring is a combined estrogen‑progestogen vaginal ring indicated for hormonal contraception. It provides a reversible, user‑controlled method to prevent pregnancy in women of reproductive age by delivering continuous low‑dose ethynylestradiol and etonogestrel directly to the vaginal mucosa.

Ethinylestradiol activates estrogen receptors while etonogestrel binds progesterone receptors. Together they suppress the hypothalamic‑pituitary‑gonadal axis, lowering LH and FSH secretion, which blocks follicular development and ovulation. The progestogen also thickens cervical mucus and modifies the endometrium, creating conditions that impede sperm penetration and implantation.

The prescriber determines the appropriate regimen for each patient. Typically, a single Myring vaginal ring is inserted and left in place for three weeks, followed by a ring‑free week, but exact dosing and duration are individualized based on clinical judgment and patient preference.

Myring is contraindicated during pregnancy because it is designed to prevent conception. For breastfeeding women, limited data exist; most clinicians advise caution during the early postpartum period and recommend discussing alternatives with a healthcare professional.

To request Myring, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will ask for trade or institutional credentials. The sales team then replies with pricing, availability, shipping details (including any cold‑chain requirements) and the necessary import documentation.

Myring offers a vaginal delivery system, whereas the most common alternative is the combined oral contraceptive pill. The ring provides steady hormone release, eliminates daily dosing, and may have a lower gastrointestinal side‑effect profile, while oral pills allow more flexible dosing adjustments. Both share similar efficacy and safety considerations.

Myring should be stored at ambient temperature, below 25 °C, in its original sealed packaging. Keep the product away from moisture, direct sunlight, and extreme heat to maintain the integrity of the polymer matrix that controls hormone release.

A healthcare professional or the patient inserts the flexible vaginal ring into the upper vaginal vault using a clean hand. The ring remains in place for three consecutive weeks, after which it is removed and discarded. A new ring is then inserted after a one‑week ring‑free interval.

Serious adverse events include thromboembolic disorders such as deep‑vein thrombosis or pulmonary embolism, cerebrovascular accidents (stroke), myocardial infarction, and severe hepatic complications like hepatic adenoma. Any sudden chest pain, shortness of breath, severe headache, visual changes, or abdominal pain should prompt immediate medical evaluation.

Myring is contraindicated in women with a history of thromboembolic disease, uncontrolled hypertension, known or suspected estrogen‑dependent malignancies, active liver disease, or those who are pregnant. It should also be avoided in smokers over 35 years of age and in individuals taking medications that significantly reduce contraceptive efficacy without appropriate backup methods.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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