Product image of Mytolac (Lanreotide) supplied by GNH India

Mytolac

Active Ingredient:
Lanreotide
Origin:
EU

Mytolac (Lanreotide)

Lanreotide, the active ingredient in Mytolac, is a somatostatin analog presented as a subcutaneous formulation for injection use. It is employed to control excess growth hormone in acromegaly and to inhibit hormone secretion and tumor growth in gastroenteropancreatic neuroendocrine tumors.

GNH India supplies Mytolac as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, oncology centres and pharmacies worldwide. The company adheres to stringent quality standards and provides regulatory‑approved product documentation for global distribution. It offers reliable logistics and supports clinical teams with technical assistance.

Manufacturer / TM Owner

Amdipharm Limited

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Indications & Clinical Uses

Mytolac, a somatostatin analog, is used in endocrine and neuroendocrine disease pathways to suppress hormone secretion.

  • Acromegaly: reduces excess growth hormone levels and normalizes insulin‑like growth factor‑1.
  • Gastroenteropancreatic neuroendocrine tumors: slows tumor progression and controls hormone‑related symptoms.
  • Carcinoid syndrome: alleviates flushing, diarrhea and abdominal pain by inhibiting serotonin release.

How It Works

  • Lanreotide is a synthetic analogue of the peptide hormone somatostatin. After subcutaneous injection it binds with high affinity to somatostatin receptor subtypes 2 and 5 on pituitary and neuroendocrine cells, inhibiting adenylate cyclase activity and reducing cyclic AMP formation. This receptor activation suppresses the secretion of growth hormone, insulin‑like growth factor‑1, and various gastrointestinal hormones, thereby limiting tumor growth and hormone‑driven clinical manifestations.

Side Effects

The most frequently reported reactions to Mytolac are related to its injection route and hormonal modulation.

Common Side Effects

  • Injection site pain or erythema
  • Diarrhea
  • Nausea
  • Headache

Serious or Rare Side Effects

  • Gallbladder disease or gallstones
  • Acute pancreatitis
  • Severe hypersensitivity reactions (anaphylaxis)

Precautions & Warnings

When prescribing Mytolac, clinicians should consider several safety measures to minimise risks.

  • Monitor blood glucose: patients may develop hyperglycemia or worsening diabetes.
  • Assess gallbladder status: prolonged therapy can promote gallstone formation.
  • Watch for signs of pancreatitis: discontinue if severe abdominal pain or elevated enzymes occur.
  • Evaluate for hypersensitivity: avoid in individuals with known allergy to lanreotide or other somatostatin analogues.
  • Adjust in renal or hepatic impairment: use caution and consider dose modification in severe dysfunction.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Lanreotide may alter the activity of other medicines, requiring clinical attention.

Major Interactions (Avoid)

  • Concomitant use with other somatostatin analogues (e.g., octreotide) may cause excessive hormonal suppression.
  • Insulin or oral hypoglycemic agents: lanreotide can reduce insulin requirements, risking hypoglycemia.
  • Cytochrome P450 substrates metabolised by CYP3A4: potential altered plasma levels.

Moderate Interactions (Monitor Closely)

  • Antidepressants (SSRIs) and antipsychotics: possible additive effects on glucose metabolism.
  • Anticoagulants such as warfarin: monitor INR as hormonal changes may affect coagulation.
  • Thyroid hormone replacement: assess thyroid function tests periodically.

Frequently Asked Questions

Mytolac is indicated for the treatment of acromegaly, a condition caused by excess growth hormone, and for gastroenteropancreatic neuroendocrine tumors where it helps control tumor growth and hormone‑related symptoms. It is also used to manage carcinoid syndrome symptoms such as flushing and diarrhea.

Lanreotide mimics the natural hormone somatostatin and binds to somatostatin receptors, mainly subtypes 2 and 5. This binding blocks adenylate cyclase, lowers cyclic AMP, and suppresses the release of growth hormone, insulin‑like growth factor‑1, and various gastrointestinal hormones, thereby reducing tumor activity and hormone‑driven effects.

The dose and frequency of Mytolac are individualized by the prescribing clinician based on the specific indication, disease severity, patient response, and any relevant comorbidities. The prescriber will decide the appropriate regimen and may adjust it over time according to clinical monitoring.

Safety data for lanreotide in pregnancy and lactation are limited. It is generally advised to avoid use unless the potential benefit justifies the potential risk to the fetus or infant. Women who are pregnant, planning pregnancy, or breastfeeding should discuss alternatives with their healthcare provider.

To request Mytolac, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain handling if needed) and any required import documentation.

Both lanreotide and octreotide belong to the somatostatin analogue class and share similar mechanisms. Lanreotide typically has a longer half‑life, allowing for less frequent dosing (often every 4 weeks) compared with octreotide, which may require daily or twice‑daily injections. Efficacy in controlling hormone levels is comparable, but the choice depends on patient preference, tolerability and clinical judgment.

Mytolac should be stored in a refrigerator at 2‑8 °C (36‑46 °F). Keep the product in its original packaging, protect it from light, and do not freeze or shake the vial. If temporary storage at room temperature is unavoidable, limit exposure to no more than 24 hours and return it to refrigeration promptly.

Mytolac is given as a subcutaneous injection, usually into the abdomen or thigh. The healthcare professional prepares the dose using aseptic technique, selects an appropriate injection site, and administers the medication at a 45‑degree angle. Patients should be instructed on proper site rotation and disposal of used needles according to local regulations.

Serious adverse events, although uncommon, include gallbladder disease or gallstone formation, acute pancreatitis, and severe hypersensitivity reactions such as anaphylaxis. Patients should be monitored for abdominal pain, jaundice, or signs of allergic reaction, and the medication should be discontinued promptly if any of these events occur.

Mytolac is contraindicated in individuals with a known hypersensitivity to lanreotide or any component of the formulation. Caution is also advised for patients with severe hepatic impairment, uncontrolled diabetes, or active gallbladder disease. The prescriber should evaluate each patient’s medical history before initiating therapy.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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