Product image of Mytolac (Lanreotide Acetate) supplied by GNH India

Mytolac

Active Ingredient:
Lanreotide Acetate
Origin:
EU

Mytolac (Lanreotide Acetate)

Lanreotide acetate, the active ingredient in Mytolac, is a somatostatin analog presented as a subcutaneous formulation for injection use. It is employed in the management of hormone‑secreting disorders such as acromegaly and certain neuroendocrine tumors, acting to suppress excess hormone release in adult patients.

GNH India supplies Mytolac as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, oncology centres and pharmacies worldwide.

Manufacturer / TM Owner

Amdipharm Limited

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Indications & Clinical Uses

  • Mytolac, a somatostatin analog, is used to control hormone‑driven conditions within the endocrine and neuroendocrine disease spectrum.
  • Acromegaly: reduces excess growth hormone production and helps normalize insulin‑like growth factor‑1 levels.
  • Neuroendocrine tumors: inhibits tumor‑related hormone secretion, improving symptom control.
  • Carcinoid syndrome: diminishes flushing and diarrhoea by blocking serotonin and other vasoactive substances.

How It Works

  • Lanreotide acetate is a synthetic analogue of somatostatin that binds with high affinity to somatostatin receptors, primarily SSTR2 and SSTR5. Receptor activation inhibits adenylate cyclase activity, reduces intracellular calcium, and suppresses the exocytosis of several hormones, including growth hormone, insulin, glucagon, and various peptide mediators released by neuroendocrine cells.

Side Effects

Mytolac may cause a range of adverse reactions, most of which are mild to moderate in severity.

Common Side Effects

  • Injection site pain or erythema.
  • Nausea or vomiting.
  • Diarrhoea or abdominal discomfort.
  • Headache.
  • Hyperglycaemia or altered glucose tolerance.
  • Fatigue.

Serious or Rare Side Effects

  • Gallstone formation or biliary colic.
  • Acute pancreatitis.
  • Severe allergic reactions, including anaphylaxis.
  • Cardiac arrhythmias.
  • Pituitary apoplexy in patients with pre‑existing adenomas.
  • Severe hyperglycaemia requiring medical intervention.

Precautions & Warnings

  • Before initiating Mytolac, clinicians should consider several safety measures.
  • Monitor glucose levels: patients may develop hyperglycaemia, especially those with diabetes.
  • Assess gallbladder status: prolonged therapy can increase the risk of gallstones.
  • Screen for pancreatitis: watch for persistent abdominal pain or elevated enzymes.
  • Evaluate cardiac function: rare arrhythmias have been reported.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Mytolac can interact with other agents that affect hormone levels or gastrointestinal motility.

Major Interactions (Avoid)

  • Concomitant use with other somatostatin analogues (e.g., octreotide) may cause additive hormonal suppression.
  • Strong CYP450 inhibitors that alter peptide metabolism, potentially increasing exposure.
  • Antidiabetic drugs: risk of hypoglycaemia if glucose control improves markedly.

Moderate Interactions (Monitor Closely)

  • Oral glucose tolerance agents: dose adjustments may be needed.
  • Medications that delay gastric emptying (e.g., anticholinergics) could exacerbate gastrointestinal side effects.
  • Warfarin: monitor INR as rare reports suggest altered coagulation parameters.

Frequently Asked Questions

Mytolac is prescribed for patients with acromegaly, neuroendocrine tumors, and carcinoid syndrome. In each case, the drug helps control excessive hormone secretion that drives disease symptoms, providing clinical benefit when other therapies are insufficient or unsuitable.

Lanreotide acetate mimics natural somatostatin and binds to somatostatin receptors, especially SSTR2 and SSTR5. This binding blocks intracellular signaling pathways that trigger hormone release, thereby reducing levels of growth hormone, insulin, glucagon, and other peptides involved in the targeted diseases.

The dosage of Mytolac is individualized by the prescribing clinician based on the patient’s condition, disease severity, and response to therapy. Healthcare professionals determine the appropriate amount, frequency, and duration of treatment according to current clinical guidelines.

Safety data for Mytolac in pregnancy and lactation are limited, and the product’s pregnancy category is not established. It should only be used if the potential benefit justifies any potential risk to the fetus or infant, and decisions should be made in consultation with a qualified healthcare provider.

To request Mytolac, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain logistics if needed), and any required import documentation.

Mytolac (lanreotide acetate) and other somatostatin analogues such as octreotide share a similar mechanism of receptor binding but differ in formulation, dosing frequency, and pharmacokinetic profile. Lanreotide often allows for longer dosing intervals, which can improve patient convenience, while efficacy and safety are comparable when used appropriately.

Mytolac should be stored refrigerated at 2‑8 °C, protected from light, and must not be frozen or shaken. Keeping the product in its original packaging helps maintain stability and ensures potency until the point of administration.

Mytolac is given by subcutaneous injection, typically performed by a healthcare professional or a trained patient/caregiver. The injection is administered into the fatty tissue of the abdomen or thigh, following aseptic technique and the specific instructions provided by the prescriber.

Serious adverse events linked to Mytolac include gallstone formation, acute pancreatitis, severe allergic reactions (including anaphylaxis), and cardiac arrhythmias. Patients should be monitored for signs such as severe abdominal pain, jaundice, difficulty breathing, or irregular heartbeat, and seek immediate medical attention if these occur.

Mytolac is contraindicated in patients with known hypersensitivity to lanreotide acetate or any excipients in the formulation. Caution is also advised for individuals with uncontrolled diabetes, active gallbladder disease, or severe cardiac conditions, and it should be avoided in those where the risk outweighs potential benefit.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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