Product image of Mytolac (Lanreotide Acetate) supplied by GNH India

Mytolac

Active Ingredient:
Lanreotide Acetate
Origin:
EU

Mytolac (Lanreotide Acetate)

Lanreotide acetate, the active ingredient in Mytolac, is a somatostatin analog presented as a sterile injectable solution for subcutaneous use. It is employed to manage hormone‑secreting tumors and growth‑hormone disorders in adult patients, including conditions such as acromegaly and carcinoid syndrome.

GNH India supplies Mytolac as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, oncology centres and pharmacies worldwide, with a focus on reliable cold‑chain logistics and regulatory compliance for global markets. Our distribution network ensures timely delivery to clinical sites across Europe, Asia and the Americas.

Manufacturer / TM Owner

Amdipharm Limited

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Indications & Clinical Uses

  • Mytolac, a somatostatin analog, is used to control hormone‑secreting tumors and related endocrine disorders.
  • Acromegaly: reduces excess growth hormone and IGF‑1 levels, improving symptoms and associated metabolic complications.
  • Neuroendocrine tumors (carcinoid syndrome): decreases secretion of vasoactive peptides, alleviating flushing, diarrhea and abdominal pain.
  • Cushing's disease (off‑label): lowers ACTH production, helping to control cortisol excess.

How It Works

  • Lanreotide acetate is a synthetic analogue of somatostatin that binds with high affinity to somatostatin receptor subtypes SSTR2 and SSTR5. Receptor activation inhibits adenylate cyclase activity, reducing cyclic AMP formation and suppressing the release of growth hormone, insulin‑like growth factor‑1, ACTH, and various gastrointestinal hormones, thereby controlling hormone‑driven disease processes.

Side Effects

Mytolac may cause a range of adverse reactions, which are categorized by frequency.

Common Side Effects

  • Injection site pain or erythema
  • Nausea or vomiting
  • Diarrhea or abdominal discomfort
  • Headache
  • Hyperglycemia or altered glucose tolerance
  • Fatigue

Serious or Rare Side Effects

  • Gallbladder disease, including cholelithiasis
  • Acute pancreatitis
  • Severe hyperglycemia or diabetic ketoacidosis
  • Allergic reactions such as anaphylaxis
  • Cardiovascular events (e.g., arrhythmia, ischemia)
  • Pituitary apoplexy in patients with pre‑existing adenomas

Precautions & Warnings

  • Before initiating Mytolac, clinicians should consider several safety measures.
  • Monitor glucose: patients with diabetes may experience altered blood‑sugar control.
  • Assess gallbladder: increased risk of gallstones; consider baseline imaging.
  • Evaluate pancreatic function: watch for signs of pancreatitis.
  • Review cardiac status: use cautiously in patients with known heart disease.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Mytolac can interact with other medicines; awareness of the interaction level guides management.

Major Interactions (Avoid)

  • Concomitant cyclosporine: may increase lanreotide exposure.
  • Use with other somatostatin analogs: additive hormonal suppression.
  • Combination with insulin or sulfonylureas: risk of severe hypoglycemia.

Moderate Interactions (Monitor Closely)

  • Co‑administration with dopamine agonists: potential additive endocrine effects.
  • Oral contraceptives: possible reduced efficacy.
  • Warfarin or other anticoagulants: monitor INR and adjust dose as needed.

Frequently Asked Questions

Mytolac is prescribed for the management of acromegaly, neuroendocrine tumors that cause carcinoid syndrome, and, on an off‑label basis, Cushing's disease. In each case, the drug helps to suppress excess hormone production that drives disease symptoms.

Lanreotide acetate mimics natural somatostatin and binds to somatostatin receptors SSTR2 and SSTR5 on target cells. This binding blocks intracellular signaling pathways that normally stimulate the release of growth hormone, ACTH, insulin‑like growth factor‑1, and various gastrointestinal hormones, thereby reducing pathological hormone levels.

The dosing regimen for Mytolac is individualized and must be determined by a qualified prescriber based on the patient’s specific condition, disease severity, and response to therapy. Clinicians adjust the dose and injection interval according to clinical guidelines and patient monitoring.

Safety data for lanreotide acetate in pregnancy and lactation are limited. The drug should only be used if the potential benefit to the mother outweighs any possible risk to the fetus or infant. Women who are pregnant, planning pregnancy, or breastfeeding should discuss risks with their healthcare provider.

To request Mytolac, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain handling if needed) and any required import documentation.

Both Mytolac (lanreotide) and octreotide belong to the somatostatin analog class and share similar mechanisms of receptor binding. Lanreotide typically offers a longer dosing interval, allowing monthly or quarterly injections, whereas octreotide often requires more frequent dosing. Choice of therapy depends on patient preference, disease characteristics, and physician assessment.

Mytolac should be stored refrigerated at 2‑8 °C. Keep the product in its original packaging, protect it from light, and avoid freezing or shaking the vial. If temporary storage at room temperature is unavoidable, limit exposure to no more than 30 minutes before use.

Mytolac is given as a subcutaneous injection, usually into the abdomen or thigh. The injection is performed by a trained healthcare professional or, after proper instruction, by the patient or caregiver. The injection site should be rotated to minimize local irritation.

Serious adverse events include gallbladder disease (such as cholelithiasis), acute pancreatitis, severe hyperglycemia or diabetic ketoacidosis, allergic reactions including anaphylaxis, and cardiovascular complications. Patients should be monitored regularly for these conditions, and any concerning symptoms should prompt immediate medical evaluation.

Mytolac is contraindicated in patients with known hypersensitivity to lanreotide acetate or any excipients in the formulation. Caution is advised for individuals with severe uncontrolled diabetes, active gallbladder disease, pancreatitis, or significant cardiac disorders. The drug should also be avoided in patients for whom a somatostatin analog is medically inappropriate.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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