Product image of Myviolet (Drospirenone, Ethinylestradiol) supplied by GNH India

Myviolet

Active Ingredient:
Drospirenone, Ethinylestradiol
Origin:
EU

Myviolet (Drospirenone, Ethinylestradiol)

Drospirenone, the active ingredient in Myviolet, is a combined oral contraceptive presented as an oral tablet for oral use. It prevents pregnancy in women of reproductive age by suppressing ovulation and altering cervical mucus. The formulation also contains ethinylestradiol, a synthetic estrogen that works synergistically to provide reliable contraception and menstrual cycle control.

GNH India supplies Myviolet as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies, clinics and procurement teams worldwide.

Manufacturer / TM Owner

Exeltis Italia Srl

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Indications & Clinical Uses

  • Myviolet, a combined oral contraceptive, acts on the hormonal regulation pathway to prevent unintended pregnancy.
  • Prevention of pregnancy: provides reliable contraception for women of reproductive age.
  • Regulation of menstrual cycles: helps achieve more predictable bleeding patterns and reduces dysmenorrhea.
  • Management of moderate acne: combined hormonal action can improve acne symptoms in some women.

How It Works

  • Drospirenone is a synthetic progestogen with anti‑mineralocorticoid and anti‑androgenic activity, while ethinylestradiol is a potent estrogen. Together they suppress the hypothalamic‑pituitary‑gonadal axis, inhibiting the mid‑cycle surge of luteinizing hormone and follicle‑stimulating hormone, thereby preventing ovulation. They also thicken cervical mucus and induce endometrial changes that reduce the likelihood of implantation.

Side Effects

Myviolet may cause a range of adverse reactions, varying from mild to serious.

Common Side Effects

  • Nausea
  • Breast tenderness
  • Headache
  • Weight gain
  • Mood changes
  • Spotting between periods

Serious or Rare Side Effects

  • Venous thromboembolism (deep vein thrombosis, pulmonary embolism)
  • Arterial thrombosis (stroke, myocardial infarction)
  • Hypertension
  • Liver disorders (cholestasis, hepatic dysfunction)
  • Gallbladder disease (cholelithiasis)
  • Severe allergic reactions (anaphylaxis, angioedema)

Precautions & Warnings

  • Before prescribing Myviolet, clinicians should evaluate several safety considerations.
  • Assess cardiovascular risk: evaluate history of thromboembolic events, hypertension, or smoking.
  • Screen for hepatic impairment: liver disease may affect hormone metabolism.
  • Consider smoking status: advise women over 35 who smoke to avoid use.
  • Review concomitant medications: avoid strong enzyme inducers and monitor interactions.
  • Counsel on missed doses: provide guidance on what to do if a tablet is omitted.
  • Store at ambient temperature: keep in original packaging, protect from moisture and heat.

Avoid Interactions

Myviolet can interact with other medicines, altering its effectiveness or safety.

Major Interactions (Avoid)

  • Strong CYP3A4 inducers (e.g., rifampin, carbamazepine, phenytoin): may markedly reduce contraceptive efficacy.
  • Other estrogen‑containing products (e.g., hormone therapy, estrogen patches): increase risk of thromboembolic events.
  • Anticoagulants (e.g., warfarin): may enhance bleeding risk.

Moderate Interactions (Monitor Closely)

  • Azole antifungals (e.g., ketoconazole, itraconazole): can increase hormone plasma levels.
  • Selective serotonin reuptake inhibitors (e.g., fluoxetine, sertraline): may affect bleeding patterns.
  • Herbal supplements such as St. John’s wort: may lower contraceptive effectiveness.

Frequently Asked Questions

Myviolet is a combined oral contraceptive indicated for the prevention of pregnancy in women of reproductive age. It works by inhibiting ovulation and creating cervical mucus changes that reduce the chance of fertilisation. In some regions it may also be prescribed to help regulate menstrual cycles and improve moderate acne.

Drospirenone is a synthetic progestogen with anti‑mineralocorticoid and anti‑androgenic properties, while ethinylestradiol is a potent estrogen. Together they suppress the hypothalamic‑pituitary‑gonadal axis, preventing the luteinizing hormone surge that triggers ovulation. They also thicken cervical mucus and modify the endometrium, making implantation unlikely.

The dosing regimen for Myviolet is determined by the prescribing healthcare professional. Typically, the product is taken as one tablet daily at the same time each day, following the specific cycle schedule indicated on the prescription label. Patients should follow their prescriber’s instructions and not alter the regimen without medical advice.

Myviolet is intended for use only when pregnancy is not desired; it should be discontinued if pregnancy is confirmed. The safety of combined oral contraceptives during pregnancy has not been established, and they are generally not recommended. Limited data exist for use while breastfeeding, and clinicians usually advise alternative contraception during lactation.

To order Myviolet, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, and will request verification of trade or institutional credentials. After confirmation, the sales team provides pricing, availability, shipping details and any necessary import documentation.

Myviolet contains drospirenone, which offers anti‑mineralocorticoid and anti‑androgenic effects that may reduce water retention and improve acne compared with some other progestins. Its efficacy in preventing pregnancy is comparable to other combined oral contraceptives, but the side‑effect profile can differ, with a potentially lower incidence of certain hormonal side effects.

Myviolet tablets should be stored at ambient temperature, below 25 °C, in the original blister pack to protect them from moisture and light. Keep the medication out of reach of children and do not use after the expiration date printed on the packaging.

Myviolet is taken orally, usually as a single tablet each day at the same time. The tablets are typically packaged for a 21‑day active phase followed by a 7‑day hormone‑free interval, during which withdrawal bleeding occurs. Patients should follow the specific cycle instructions provided by their prescriber.

The most serious risks include venous or arterial thromboembolism (such as deep‑vein thrombosis, pulmonary embolism, stroke, or myocardial infarction), hypertension, and severe liver disorders. Women should seek immediate medical attention if they experience unexplained leg pain, chest pain, severe headache, visual changes, or signs of liver dysfunction.

Myviolet is contraindicated in women with a history of thromboembolic disorders, uncontrolled hypertension, active liver disease, known or suspected breast cancer, or those who are pregnant. It should also be avoided by smokers over 35 years of age and by individuals taking strong CYP3A4‑inducing medications that could reduce contraceptive effectiveness.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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