Product image of Nabilone supplied by GNH India

Nabilone

Active Ingredient:
Nabilone
Origin:
EU

Nabilone

Nabilone, the active ingredient in Nabilone, is a synthetic cannabinoid presented as an oral tablet for oral use. It is employed to alleviate chemotherapy‑induced nausea and vomiting, postoperative nausea and vomiting, and to stimulate appetite in patients with AIDS‑related weight loss.

GNH India supplies Nabilone as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, oncology centres, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory‑compliant documentation for global distribution. Customers benefit from reliable lead times and dedicated technical support throughout the procurement process.

Manufacturer / TM Owner

Mylan Products Limited

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

  • Nabilone is a synthetic cannabinoid used to manage nausea and vomiting across several clinical settings.
  • Chemotherapy-induced nausea and vomiting: reduces frequency and severity of nausea and vomiting in patients receiving cytotoxic therapy.
  • Postoperative nausea and vomiting: helps prevent and treat nausea and vomiting after surgical procedures.
  • AIDS-related anorexia and weight loss: stimulates appetite and promotes weight gain in patients with HIV/AIDS.

How It Works

  • Nabilone acts as a partial agonist at cannabinoid CB1 receptors in the central nervous system. By binding to these G‑protein‑coupled receptors, it modulates neurotransmitter release involved in the emetic reflex, thereby decreasing the sensation of nausea and the motor response of vomiting. Its partial agonist activity provides antiemetic effects while limiting the intensity of cannabinoid‑related psychoactive effects. Its oral absorption allows systemic distribution, reaching brain regions that control the vomiting center.

Side Effects

Nabilone may cause a range of adverse reactions, which are categorized by frequency and severity.

Common Side Effects

  • Drowsiness: feeling unusually sleepy or fatigued.
  • Dry mouth: reduced salivation leading to throat discomfort.
  • Dizziness: sensation of lightheadedness or imbalance.
  • Euphoria or mood changes: mild alterations in mood or perception.
  • Nausea: paradoxical feeling of nausea.
  • Vomiting: occasional episodes despite antiemetic action.

Serious or Rare Side Effects

  • Psychosis: hallucinations, delusions, or severe confusion.
  • Severe hypotension: marked drop in blood pressure causing faintness.
  • Allergic reactions: rash, itching, swelling, or anaphylaxis.
  • Seizures: rare occurrence of convulsive episodes.

Precautions & Warnings

  • When prescribing Nabilone, clinicians should consider several precautionary measures to ensure safe use.
  • Assess hepatic function: adjust use in patients with severe liver impairment.
  • Monitor for psychiatric symptoms: watch for anxiety, depression, or psychotic changes.
  • Avoid concurrent CNS depressants: increased sedation risk with alcohol or opioids.
  • Pregnancy and lactation: use only if potential benefit justifies potential risk.
  • Driving and machinery: caution due to possible dizziness or drowsiness.
  • Store at ambient temperature: keep below 25°C in original container, protect from moisture.

Avoid Interactions

Nabilone can interact with other medicines, affecting its efficacy or safety.

Major Interactions (Avoid)

  • CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin): may increase Nabilone plasma levels, raising risk of toxicity.
  • Centrally acting depressants (e.g., benzodiazepines, opioids): can enhance sedation and respiratory depression.

Moderate Interactions (Monitor Closely)

  • CYP3A4 inducers (e.g., rifampin, carbamazepine): may reduce Nabilone effectiveness.
  • Anticholinergic agents: may exacerbate dry mouth.
  • Antihypertensives: possible additive hypotensive effect.

Frequently Asked Questions

Nabilone is prescribed to treat nausea and vomiting that result from chemotherapy, surgery, or AIDS‑related weight loss. It helps patients who have not responded adequately to conventional antiemetics by targeting the cannabinoid pathways that control the emetic response.

Nabilone works as a partial agonist at cannabinoid CB1 receptors in the brain. Activation of these receptors modulates neurotransmitter release involved in the vomiting reflex, thereby reducing the sensation of nausea and the physical act of vomiting.

The dosage of Nabilone is individualized. A qualified prescriber determines the appropriate strength, frequency, and duration based on the patient’s clinical condition, response, and tolerance. No fixed regimen should be assumed without professional guidance.

Safety data for Nabilone in pregnancy and lactation are limited. It should be used only if the potential benefit outweighs the possible risk to the fetus or infant, and the decision must be made by the treating physician.

To request Nabilone, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with standard antiemetics such as ondansetron, Nabilone targets the cannabinoid system rather than serotonin receptors, offering an alternative mechanism of action. It is often considered when patients have inadequate control with first‑line agents. Dronabinol is another synthetic cannabinoid with a similar profile, but Nabilone may have a slightly different side‑effect spectrum.

Nabilone tablets should be stored at ambient temperature, below 25 °C, in the original packaging to protect them from moisture and light. Keep the product out of reach of children and do not use after the expiration date.

Nabilone is taken orally, usually with a glass of water. It can be taken with or without food, but consistent administration with respect to meals helps maintain stable blood levels. Patients should follow the prescriber’s instructions regarding timing and dosing.

Serious adverse events include psychosis or severe mood disturbances, marked hypotension that can cause fainting, and rare seizures. Patients should be monitored for any sudden changes in mental status, blood pressure, or neurological symptoms, and medical attention sought promptly if these occur.

Nabilone is contraindicated in individuals with known hypersensitivity to the drug, severe hepatic impairment, active psychotic disorders, or in patients where the risk outweighs benefit, such as certain pregnant or breastfeeding women. A healthcare professional should evaluate each case before initiating therapy.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Nabilone

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT