Product image of Nac 200 Akut 1 A Pharma (Acetylcysteine) supplied by GNH India

Nac 200 Akut 1 A Pharma

Active Ingredient:
Acetylcysteine
Origin:
EU

Nac 200 Akut 1 A Pharma (Acetylcysteine)

Acetylcysteine, the active ingredient in Nac 200 Akut 1 A Pharma, is a mucolytic agent presented as an oral formulation for oral use. It reduces mucus viscosity in respiratory conditions such as chronic bronchitis, COPD and acute respiratory infections.

GNH India supplies Nac 200 Akut 1 A Pharma as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

1 A Pharma Gmbh

1
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Indications & Clinical Uses

Acetylcysteine is used as a mucolytic in various respiratory disorders.

  • Chronic bronchitis: improves clearance of thickened bronchial secretions.
  • Chronic obstructive pulmonary disease (COPD): facilitates expectoration and reduces cough frequency.
  • Acute respiratory infections: aids in the removal of mucus plugs and eases breathing.
  • Post‑operative pulmonary care: helps prevent atelectasis by thinning secretions.

How It Works

  • Acetylcysteine acts by cleaving disulfide bonds within mucopolysaccharide glycoproteins, thereby reducing the viscosity and elasticity of mucus. This chemical modification lowers the tensile strength of the mucus gel, allowing ciliary action and cough to more effectively transport secretions out of the airways.

Side Effects

Acetylcysteine may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects

  • Nausea
  • Vomiting
  • Unpleasant taste or odor
  • Abdominal discomfort
  • Headache
  • Mild skin rash

Serious or Rare Side Effects

  • Anaphylactic reaction
  • Severe skin reactions (e.g., Stevens‑Johnson syndrome)
  • Bronchospasm, especially in asthmatic patients
  • Hepatic enzyme elevation
  • Neutropenia or other blood dyscrasias
  • Hypotension when combined with nitroprusside

Precautions & Warnings

When using acetylcysteine, consider the following safety measures.

  • Renal function assessment: adjust use in patients with severe renal impairment.
  • Hepatic monitoring: observe liver enzymes during prolonged therapy.
  • Asthma caution: monitor for bronchospasm, especially after inhaled administration.
  • Hypersensitivity: discontinue if signs of allergic reaction appear.
  • Elderly patients: start with lower doses and monitor tolerance.
  • Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Acetylcysteine can influence the activity of several concomitant medicines.

Major Interactions (Avoid)

  • Nitroprusside: co‑administration may potentiate hypotensive effects.
  • Activated charcoal: reduces acetylcysteine absorption if given within 2 hours.

Moderate Interactions (Monitor Closely)

  • Penicillins (e.g., ampicillin): possible reduction in antibacterial efficacy.
  • Carbamazepine: acetylcysteine may increase its metabolism, lowering plasma levels.
  • Oral contraceptives: potential decrease in hormonal effectiveness.
  • Anticoagulants (e.g., warfarin): monitor INR as acetylcysteine may affect clotting parameters.

Frequently Asked Questions

Nac 200 Akut 1 A Pharma contains acetylcysteine, a mucolytic that helps thin and loosen thick mucus in the airways. It is used to improve clearance of secretions in conditions such as chronic bronchitis, chronic obstructive pulmonary disease (COPD) and acute respiratory infections, facilitating easier breathing and expectoration.

Acetylcysteine reduces mucus viscosity by breaking disulfide bonds within mucopolysaccharide glycoproteins. This chemical action decreases the elasticity of mucus, allowing ciliary movement and cough to more effectively transport secretions out of the respiratory tract, thereby improving airway patency.

The appropriate dose of Nac 200 Akut 1 A Pharma is determined by the prescribing healthcare professional based on the patient’s condition, age, weight and renal function. The prescriber will specify the exact regimen and any necessary adjustments.

Safety data for acetylcysteine in pregnancy and lactation are limited. It should only be used if the potential benefit to the mother outweighs any possible risk to the fetus or infant, and this decision must be made by a qualified healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, indicating the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Acetylcysteine is a thiol‑containing mucolytic that directly cleaves disulfide bonds, whereas other agents such as carbocisteine or ambroxol primarily modify mucus production or increase ciliary activity. Acetylcysteine’s antioxidant properties also provide additional benefits in certain pulmonary conditions.

Store the product at ambient temperature, preferably below 25 °C. Keep it in the original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed to maintain product stability.

The medication is taken orally as directed by the prescriber. It may be administered with or without food, depending on the specific instructions provided. Swallow the tablet or capsule whole; do not crush or chew unless explicitly advised.

Serious adverse events, although rare, include anaphylaxis, severe skin reactions such as Stevens‑Johnson syndrome, bronchospasm (particularly in asthmatic patients), significant hepatic enzyme elevation, and hematologic abnormalities like neutropenia. Immediate medical attention is required if any of these occur.

Patients with a known hypersensitivity to acetylcysteine or any of the product’s excipients should avoid its use. Caution is also advised for individuals with severe asthma, uncontrolled hepatic disease, or those receiving nitroprusside, due to the risk of enhanced hypotensive effects.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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