Product image of Naclof (Diclofenac Sodium) supplied by GNH India

Naclof

Active Ingredient:
Diclofenac Sodium
Origin:
EU

Naclof (Diclofenac Sodium)

Diclofenac Sodium, the active ingredient in Naclof, is a Nonsteroidal anti-inflammatory drug (NSAID) presented as an ophthalmic solution for ocular use. It reduces inflammation and pain in eye tissues after surgery or in allergic conditions.
GNH India supplies Naclof as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Laboratoires Thea

1
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Indications & Clinical Uses

  • Diclofenac Sodium ophthalmic solution is used to manage inflammation and pain in ocular conditions.
  • Post‑operative ocular inflammation: reduces swelling and discomfort after eye surgery.
  • Post‑operative ocular pain: alleviates pain following cataract or refractive procedures.
  • Allergic conjunctivitis: helps control inflammation and itching associated with allergic eye reactions.

How It Works

  • Diclofenac Sodium works by reversibly inhibiting cyclooxygenase (COX‑1 and COX‑2) enzymes in ocular tissues. This inhibition lowers prostaglandin synthesis, leading to decreased inflammatory mediators, reduced vascular permeability, and attenuation of pain signals within the eye.

Side Effects

Adverse reactions may occur with ocular diclofenac use.

Common Side Effects

  • Burning or stinging sensation upon instillation.
  • Redness of the conjunctiva.
  • Increased tearing or watery eyes.
  • Blurred vision temporarily.
  • Foreign body sensation.
  • Mild eye irritation.

Serious or Rare Side Effects

  • Corneal ulceration or perforation.
  • Severe allergic reaction such as angioedema.
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis.
  • Vision loss or significant visual impairment.
  • Marked increase in intra‑ocular pressure.
  • Persistent or worsening inflammation despite therapy.

Precautions & Warnings

  • Before using Naclof, consider the following safety measures.
  • Assess ocular surface health: ensure no active infection or corneal defects.
  • Avoid use in patients with known hypersensitivity to diclofenac or other NSAIDs.
  • Do not combine with other ocular NSAID preparations without medical guidance.
  • Monitor for signs of corneal toxicity or delayed healing.
  • Avoid contact lens wear during treatment unless advised by an eye care professional.
  • Store at room temperature: keep in the original container, protect from light and moisture.

Avoid Interactions

Diclofenac Sodium ophthalmic solution can interact with other medications.

Major Interactions (Avoid)

  • Concurrent use with other ocular NSAIDs: increased risk of corneal toxicity.
  • Systemic NSAIDs: additive systemic exposure may raise bleeding risk.
  • Anticoagulants (e.g., warfarin): potential for enhanced ocular bleeding.

Moderate Interactions (Monitor Closely)

  • Topical corticosteroids: may mask signs of infection.
  • Contact lens solutions containing preservatives: may increase ocular irritation.
  • Systemic corticosteroids: may affect wound healing and inflammation control.

Frequently Asked Questions

Naclof contains diclofenac sodium and is indicated for the treatment of postoperative ocular inflammation and pain, as well as for managing allergic conjunctivitis. It helps reduce swelling, redness, and discomfort in the eye after surgical procedures or allergic reactions.

Diclofenac sodium inhibits cyclooxygenase enzymes (COX‑1 and COX‑2) in ocular tissues, decreasing the production of prostaglandins that drive inflammation and pain. By lowering these mediators, the drug reduces swelling, redness, and discomfort in the treated eye.

The dosing regimen for Naclof is determined by the prescribing eye care professional based on the specific condition, severity, and patient factors. The prescriber will specify the number of drops, frequency, and duration of treatment.

Safety of ocular diclofenac during pregnancy or lactation has not been fully established. It should be used only if the potential benefit justifies any potential risk to the fetus or infant, and the decision should be made in consultation with a healthcare provider.

To order Naclof, submit an enquiry on the product page at gnhindia.com indicating the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Naclof (diclofenac) is a non‑steroidal anti‑inflammatory drug, offering anti‑inflammatory and analgesic effects without the steroid‑related rise in intra‑ocular pressure. Compared with corticosteroid eye drops, it has a lower risk of steroid‑induced glaucoma but may carry a higher risk of corneal irritation when used long‑term.

Store Naclof at room temperature, preferably below 25 °C, in its original packaging. Protect the container from excessive light, moisture, and heat. Ensure the cap is tightly closed to maintain sterility.

Naclof is applied as an ophthalmic solution. The prescribed number of drops is placed into the lower conjunctival sac of the affected eye(s) using the provided dropper, typically without touching the eye or eyelid. Follow the prescriber’s instructions for frequency and duration.

Serious risks include corneal ulceration or perforation, severe allergic reactions such as angioedema, Stevens‑Johnson syndrome, and significant vision loss. Patients should seek immediate medical attention if they experience persistent pain, worsening vision, or signs of severe eye irritation.

Naclof should not be used by individuals with known hypersensitivity to diclofenac, other NSAIDs, or any component of the formulation. It is also contraindicated in patients with active ocular infections, corneal ulcers, or those using other ocular NSAID products without medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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