Product image of Naclof Unidose (Diclofenac Sodium) supplied by GNH India

Naclof Unidose

Active Ingredient:
Diclofenac Sodium
Origin:
EU

Naclof Unidose (Diclofenac Sodium)

Diclofenac Sodium, the active ingredient in Naclof Unidose, is a nonsteroidal anti‑inflammatory drug (NSAID) presented as an ophthalmic solution for ocular use. It is employed to reduce inflammation and pain following eye surgery and in other inflammatory eye conditions. The formulation is designed for topical instillation into the conjunctival sac, providing localized anti‑inflammatory activity with minimal systemic exposure.

GNH India supplies Naclof Unidose as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and offers regulatory‑compliant shipping to meet the needs of global eye‑care providers.

Manufacturer / TM Owner

Laboratoires Thea

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Diclofenac sodium ophthalmic solution is indicated for ocular conditions involving inflammation and pain.

  • Post‑operative ocular inflammation: reduces swelling and redness after eye surgery.
  • Post‑operative ocular pain: provides analgesic relief following cataract or other intraocular procedures.
  • Allergic conjunctivitis: helps control inflammatory symptoms such as itching and hyperemia.

How It Works

  • Diclofenac sodium inhibits cyclooxygenase (COX‑1 and COX‑2) enzymes in ocular tissues, decreasing the synthesis of prostaglandins that mediate inflammation, vasodilation, and pain. By limiting prostaglandin production at the site of instillation, the drug reduces cellular infiltration, edema, and nociceptive signaling within the eye. The inhibition is reversible and primarily local, resulting in minimal systemic absorption when applied as eye drops.

Side Effects

Ocular administration of diclofenac sodium may be associated with a range of adverse reactions, varying from mild irritation to rare serious events.

Common Side Effects

  • Burning or stinging sensation upon instillation
  • Transient blurred vision
  • Foreign body sensation
  • Conjunctival hyperemia
  • Increased tearing
  • Mild eyelid edema

Serious or Rare Side Effects

  • Corneal ulceration or epithelial defect
  • Severe allergic reaction including angioedema
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis
  • Ocular infection or worsening inflammation
  • Significant increase in intra‑ocular pressure

Precautions & Warnings

Before using Naclof Unidose, consider the following precautions to ensure safe and effective therapy.

  • Allergy assessment: avoid if known hypersensitivity to diclofenac, other NSAIDs, or excipients.
  • Pregnancy and lactation: use only if clearly indicated after risk‑benefit evaluation by a physician.
  • Contact lens wearers: remove lenses before instillation and wait before reinserting.
  • Concurrent ocular infections: evaluate and treat infection prior to NSAID use.
  • Systemic NSAID use: monitor for additive systemic adverse effects.
  • Store at ambient temperature: keep in original container, protect from light and moisture.

Avoid Interactions

Diclofenac sodium eye drops can interact with other medications, influencing efficacy or safety.

Major Interactions (Avoid)

  • Systemic NSAIDs: concurrent use may increase risk of systemic adverse events such as gastrointestinal bleeding.
  • Anticoagulants (e.g., warfarin): may potentiate bleeding tendencies, especially after ocular surgery.

Moderate Interactions (Monitor Closely)

  • Topical corticosteroids: may affect wound healing when used together.
  • Beta‑blocker eye drops: monitor intra‑ocular pressure as NSAIDs can alter pressure dynamics.
  • Other ophthalmic NSAIDs: avoid duplication to prevent excess exposure.

Frequently Asked Questions

Naclof Unidose is an ophthalmic solution containing diclofenac sodium. It is prescribed to manage inflammation and pain in the eye, most commonly after surgical procedures such as cataract extraction, and to treat inflammatory eye conditions like allergic conjunctivitis.

Diclofenac sodium blocks the cyclooxygenase enzymes (COX‑1 and COX‑2) in ocular tissues, which reduces the formation of prostaglandins. Prostaglandins are key mediators of inflammation, swelling, and pain, so their inhibition leads to decreased ocular inflammation and analgesia.

The dosing regimen for Naclof Unidose is determined by the prescribing eye‑care professional based on the specific indication, severity of inflammation, and patient factors. The prescriber will specify the number of drops, frequency, and duration of treatment.

Safety of ocular diclofenac during pregnancy or lactation has not been fully established. It should be used only if the potential benefit justifies any possible risk to the fetus or infant, and this decision must be made by a qualified healthcare provider.

To request Naclof Unidose, submit an enquiry on the product page at gnhindia.com, indicating the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and necessary import documentation.

Naclof Unidose delivers diclofenac sodium, which has a well‑documented anti‑inflammatory profile and rapid onset of action. Compared with other ophthalmic NSAIDs such as ketorolac or bromfenac, diclofenac offers similar efficacy for postoperative inflammation, with a comparable safety profile; choice often depends on clinician preference, formulation availability, and patient tolerance.

Store Naclof Unidose at ambient temperature, preferably below 25 °C, in the original packaging. Protect the container from direct light, moisture, and extreme temperature fluctuations to maintain product stability and potency.

The solution is applied topically to the eye. The patient should wash hands, tilt the head back, gently pull down the lower eyelid, and instill the prescribed number of drops into the conjunctival sac. After dosing, keep the eyes closed for a few seconds to allow absorption and avoid immediate blinking.

Although uncommon, serious adverse events can include corneal ulceration, severe allergic reactions such as angioedema, Stevens‑Johnson syndrome, and significant increases in intra‑ocular pressure. Patients should seek immediate medical attention if they experience persistent pain, vision changes, or signs of an allergic reaction.

Individuals with known hypersensitivity to diclofenac, other NSAIDs, or any component of the formulation should avoid using Naclof Unidose. It is also contraindicated in patients with active ocular infections or uncontrolled intra‑ocular pressure unless specifically directed by an ophthalmologist.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.