Product image of Nalbuphin Amomed (Nalbuphine Hydrochloride) supplied by GNH India

Nalbuphin Amomed

Active Ingredient:
Nalbuphine Hydrochloride
Origin:
EU

Nalbuphin Amomed (Nalbuphine Hydrochloride)

Nalbuphine, the active ingredient in Nalbuphin Amomed, is an opioid analgesic presented as a sterile injectable solution for intramuscular, intravenous, or subcutaneous use. It is employed to manage moderate to severe pain in various clinical settings.
GNH India supplies Nalbuphin Amomed as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Amomed Pharma Gmbh

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

  • Nalbuphine is used in the management of pain through its mixed agonist‑antagonist activity at opioid receptors.
  • Postoperative pain: provides analgesia for moderate to severe pain after surgery.
  • Labor pain: used to relieve pain during childbirth.
  • Cancer‑related pain: incorporated into multimodal regimens for severe cancer pain.

How It Works

  • Nalbuphine acts as a kappa opioid receptor agonist while simultaneously antagonizing mu opioid receptors. This dual activity produces analgesia primarily via kappa activation and limits typical mu‑mediated effects such as respiratory depression, resulting in effective pain control with a distinct safety profile compared with pure mu agonists.

Side Effects

Adverse reactions may occur with nalbuphine administration.

Common Side Effects

  • Dizziness
  • Nausea
  • Vomiting
  • Sedation

Serious or Rare Side Effects

  • Respiratory depression
  • Hypotension
  • Allergic reactions, including anaphylaxis
  • Severe constipation or paralytic ileus

Precautions & Warnings

Clinicians should observe several safety considerations when using nalbuphine.

  • Dose adjustment in renal impairment: reduce dose and monitor renal function.
  • Use cautiously in hepatic impairment: monitor liver enzymes and clinical response.
  • Avoid in patients with known hypersensitivity to nalbuphine or its excipients.
  • Monitor for respiratory depression, especially when combined with other CNS depressants.
  • Pregnancy and lactation: safety not established; use only if benefit outweighs risk.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze.

Avoid Interactions

Nalbuphine may interact with other medicines, requiring attention to avoid adverse outcomes.

Major Interactions (Avoid)

  • Concurrent use with other opioid agonists: risk of additive respiratory depression.
  • Combination with benzodiazepines or barbiturates: heightened CNS depression.
  • MAO inhibitors: may precipitate severe hypertension or serotonin syndrome.

Moderate Interactions (Monitor Closely)

  • Anticholinergic agents: may increase risk of urinary retention.
  • CYP3A4 inhibitors (e.g., ketoconazole): may raise nalbuphine plasma concentrations.
  • CYP3A4 inducers (e.g., rifampin): may reduce analgesic efficacy.

Frequently Asked Questions

Nalbuphin Amomed contains nalbuphine, an opioid analgesic used to treat moderate to severe pain, including postoperative pain, labor pain, and cancer‑related pain, when a mixed agonist‑antagonist opioid is appropriate.

Nalbuphine activates kappa opioid receptors to produce analgesia while blocking mu opioid receptors, which reduces typical mu‑mediated effects such as respiratory depression, providing effective pain relief with a distinct safety profile.

The specific dose and dosing schedule are determined by the prescribing clinician based on the patient’s condition, pain severity, route of administration, and individual response.

Safety data for nalbuphine in pregnancy and lactation are limited. It should only be used if the potential benefit justifies any potential risk to the fetus or infant, and the decision must be made by a qualified healthcare professional.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed) and import documentation.

Unlike pure mu‑agonist opioids such as morphine, nalbuphine’s mixed agonist‑antagonist profile offers analgesia with a lower risk of respiratory depression and reduced potential for dependence, making it a useful alternative in patients where these concerns are prominent.

Nalbuphin Amomed should be stored at 2‑8 °C, protected from light, and kept in its original packaging. Do not freeze or shake the product, and ensure it remains within the recommended temperature range during transport.

The product is supplied as a sterile injectable solution and can be given intramuscularly, intravenously, or subcutaneously by a qualified healthcare professional, following aseptic technique and appropriate dosing guidelines.

Serious risks include respiratory depression, severe hypotension, allergic reactions such as anaphylaxis, and, in rare cases, profound constipation or paralytic ileus. Prompt monitoring and supportive care are essential if these events occur.

Patients with known hypersensitivity to nalbuphine or any formulation component, those taking MAO inhibitors, or individuals with severe respiratory compromise should avoid using this medication unless a specialist determines that benefits outweigh risks.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.