Product image of Nalcrom (Sodium Cromoglicate) supplied by GNH India

Nalcrom

Active Ingredient:
Sodium Cromoglicate
Origin:
EU

Nalcrom (Sodium Cromoglicate)

Sodium cromoglicate, the active ingredient in Nalcrom, is a mast cell stabilizer presented as an oral formulation for oral use. It treats allergic conditions such as allergic rhinitis, conjunctivitis, asthma prophylaxis and food allergy, primarily in patients requiring antiallergic therapy.

GNH India supplies Nalcrom as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory‑compliant packaging for export to multiple regions. Its global network ensures reliable delivery to healthcare providers across Europe, Asia, Africa and the Americas.

Manufacturer / TM Owner

Italchimici S.P.A.

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Indications & Clinical Uses

  • Nalcrom, a mast cell stabilizer, is used to manage allergic disorders by preventing mast cell degranulation.
  • Allergic rhinitis: reduces nasal congestion, sneezing and itching.
  • Allergic conjunctivitis: alleviates eye itching, redness and watery discharge.
  • Asthma prophylaxis: decreases frequency of bronchospasm episodes and improves airway stability.
  • Food allergy: helps prevent systemic allergic reactions after exposure to trigger foods.

How It Works

  • Sodium cromoglicate acts by binding to calcium channels on the surface of mast cells, stabilizing the cell membrane and inhibiting calcium‑dependent degranulation. This prevents the release of histamine, leukotrienes, prostaglandins and other inflammatory mediators that drive allergic symptoms. By blocking these pathways, the drug reduces both early‑phase and late‑phase allergic responses and contributes to overall symptom control.

Side Effects

Sodium cromoglicate is generally well tolerated, but some patients may experience adverse reactions.

Common Side Effects

  • Taste alteration: mild metallic or bitter taste.
  • Nausea: occasional stomach upset.
  • Abdominal discomfort: mild cramps or pain.
  • Headache: transient.
  • Diarrhea: loose stools.

Serious or Rare Side Effects

  • Anaphylactic reaction: severe allergic response requiring immediate medical attention.
  • Severe skin reactions: such as Stevens‑Johnson syndrome or toxic epidermal necrolysis.
  • Bronchospasm: paradoxical worsening of breathing in susceptible individuals.

Precautions & Warnings

  • Before initiating Nalcrom, consider the following precautions.
  • Pregnancy: use only if clearly needed; consult healthcare provider.
  • Breastfeeding: monitor infant for possible effects; discuss with physician.
  • Renal impairment: assess kidney function and adjust therapy if required.
  • Known hypersensitivity: avoid in patients with documented allergy to sodium cromoglicate or related compounds.
  • Concomitant medications: review all drugs for potential interactions, especially other mast cell stabilizers.
  • Store at room temperature: keep in original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Sodium cromoglicate may interact with other medicines; the following interactions are recognized.

Major Interactions (Avoid)

  • Concurrent use with other mast cell stabilizers: may increase risk of additive side effects.
  • Use with high‑dose aspirin or NSAIDs in patients with asthma: may exacerbate bronchospasm.

Moderate Interactions (Monitor Closely)

  • Antihistamines: combined effect may enhance antiallergic response; monitor symptom control.
  • Oral corticosteroids: may require dose adjustment of either agent.
  • Theophylline: possible alteration of plasma levels; monitor therapeutic response.
  • Beta‑agonists: may reduce the perceived benefit of cromoglicate; assess clinical response.

Frequently Asked Questions

Nalcrom is prescribed to manage allergic rhinitis, allergic conjunctivitis, asthma prophylaxis, and food allergy. By stabilizing mast cells, it helps reduce symptoms such as nasal congestion, eye irritation, bronchospasm, and systemic reactions after exposure to allergens.

Sodium cromoglicate binds to calcium channels on mast cells, stabilizing their membranes and preventing calcium‑dependent degranulation. This blocks the release of histamine and other inflammatory mediators, thereby reducing both early and late allergic responses.

The dosage of Nalcrom is individualized. A qualified prescriber determines the appropriate amount, frequency and duration based on the patient’s age, condition severity, and overall treatment plan.

Safety data are limited. Nalcrom should only be used during pregnancy or while breastfeeding if the potential benefit justifies any possible risk. Patients should discuss their specific situation with a healthcare professional before starting therapy.

To request Nalcrom, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Unlike antihistamines that block histamine receptors, Nalcrom prevents the release of histamine and other mediators by stabilizing mast cells. This upstream action can provide broader control of allergic inflammation, especially useful for prophylaxis in asthma and food‑triggered reactions.

Nalcrom should be stored at room temperature, below 25 °C, in its original container. Keep it away from moisture, direct sunlight and heat sources to maintain product stability throughout its shelf life.

Nalcrom is taken orally. The tablet or liquid is swallowed with water, usually at regular intervals as directed by the prescriber. It is not intended for injection or topical use.

Serious but rare risks include anaphylactic reactions, severe skin disorders such as Stevens‑Johnson syndrome, and paradoxical bronchospasm. Patients should seek immediate medical attention if they experience difficulty breathing, widespread rash or swelling.

Individuals with a known hypersensitivity to sodium cromoglicate or any component of the formulation should avoid Nalcrom. Caution is also advised for patients with severe renal impairment until a clinician evaluates the risk‑benefit profile.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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