Product image of Nalgesin S (Naproxen Sodium) supplied by GNH India

Nalgesin S

Active Ingredient:
Naproxen Sodium
Origin:
EU

Nalgesin S (Naproxen Sodium)

Naproxen sodium, the active ingredient in Nalgesin S, is a nonsteroidal anti-inflammatory drug presented as an oral tablet for oral use. It is employed to relieve mild to moderate pain, reduce inflammation in conditions such as arthritis, and lower fever in adult patients.

GNH India supplies Nalgesin S as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable global distribution for this EU‑origin NSAID. Customers benefit from consistent batch release and regulatory support.

Manufacturer / TM Owner

Krka, D.D., Novo Mesto

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Indications & Clinical Uses

Nalgesin S (naproxen sodium) acts on inflammatory pathways and is indicated for the following conditions:

  • Mild to moderate pain: provides analgesic relief by reducing prostaglandin‑mediated pain signaling.
  • Arthritis (osteoarthritis, rheumatoid arthritis): decreases joint inflammation and swelling, improving mobility.
  • Fever: lowers elevated body temperature associated with inflammatory processes.

How It Works

  • Naproxen sodium non‑selectively inhibits cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which blocks the conversion of arachidonic acid to prostaglandins. By reducing prostaglandin synthesis, it diminishes inflammation, pain perception, and fever generation at the site of tissue injury.

Side Effects

Adverse reactions may vary in frequency and severity.

Common Side Effects

  • Gastrointestinal discomfort such as nausea, dyspepsia or abdominal pain.
  • Headache or dizziness.
  • Mild skin rash or itching.
  • Elevated blood pressure.
  • Fluid retention or peripheral edema.

Serious or Rare Side Effects

  • Gastrointestinal ulceration or bleeding.
  • Severe hypersensitivity reactions, including anaphylaxis.
  • Renal impairment or failure.
  • Hepatotoxicity with elevated liver enzymes.
  • Cardiovascular events such as myocardial infarction or stroke.

Precautions & Warnings

Nalgesin S should be used with consideration of the following precautions:

  • Cardiovascular risk: avoid in patients with a history of heart disease or stroke unless advised.
  • Gastrointestinal safety: assess for ulcer disease or bleeding risk before initiating therapy.
  • Renal function: monitor kidney function in patients with existing renal impairment.
  • Hepatic health: use cautiously in individuals with liver disease.
  • Concomitant medications: review all current drugs for potential interactions.
  • Store at ambient temperature: keep below 25 °C, retain in the original packaging, and protect from moisture.

Avoid Interactions

Naproxen sodium may interact with several drug classes.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of serious bleeding.
  • Selective serotonin reuptake inhibitors (SSRIs) or other serotonergic agents: heightened bleeding potential.
  • Other NSAIDs or COX‑2 inhibitors: additive gastrointestinal toxicity.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: may reduce renal perfusion, especially in volume‑depleted patients.
  • Diuretics: potential for reduced antihypertensive effect.
  • Lithium: NSAIDs can raise lithium serum levels, requiring monitoring.

Frequently Asked Questions

Nalgesin S contains naproxen sodium, an NSAID that is commonly prescribed to relieve mild to moderate pain, reduce inflammation in arthritic conditions, and lower fever associated with inflammatory processes.

Naproxen sodium blocks both COX‑1 and COX‑2 enzymes, which prevents the formation of prostaglandins—chemicals that promote inflammation, pain, and fever—thereby providing analgesic, anti‑inflammatory, and antipyretic effects.

The appropriate dose of Nalgesin S is determined by the prescribing healthcare professional based on the patient’s age, weight, medical condition, and response to therapy. No fixed regimen is provided here.

Safety data for naproxen sodium during pregnancy and lactation are limited. It should only be used if the potential benefit justifies the potential risk to the fetus or infant, and only under medical supervision.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Both naproxen sodium (Nalgesin S) and ibuprofen are NSAIDs that inhibit COX enzymes. Naproxen generally has a longer half‑life, allowing less frequent dosing, while ibuprofen may have a slightly faster onset. Choice depends on clinical response, dosing convenience and individual safety considerations.

Store Nalgesin S at ambient temperature, preferably below 25 °C. Keep the tablets in the original container, protect them from moisture and direct sunlight, and keep out of reach of children.

Nalgesin S is taken orally, usually with a full glass of water. It may be taken with food or milk to lessen gastrointestinal discomfort, but the exact administration instructions should follow the prescribing clinician’s guidance.

Serious risks include gastrointestinal bleeding or ulceration, severe allergic reactions such as anaphylaxis, renal impairment, hepatotoxicity, and increased cardiovascular events like heart attack or stroke. Patients should seek immediate medical attention if they notice signs of these conditions.

Individuals with known hypersensitivity to naproxen or other NSAIDs, active gastrointestinal ulcer disease, severe renal or hepatic impairment, uncontrolled hypertension, or a history of cardiovascular thrombotic events should avoid using Nalgesin S unless specifically directed by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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