Naltrexon-Hcl Neuraxpharm (Naltrexone Hydrochloride)

Naltrexone hydrochloride acts as a competitive antagonist at mu, kappa and delta opioid receptors in the brain. It binds without activating the receptors, thereby preventing endogenous and exogenous opioids from producing their usual reinforcing and rewarding effects.

The dosage of Naltrexon-Hcl is individualized. A qualified prescriber determines the appropriate strength, frequency and duration based on the patient’s clinical condition, treatment goals and response to therapy.

Safety data for naltrexone hydrochloride in pregnancy and lactation are limited. It is generally advised to avoid use unless the potential benefit outweighs the possible risk to the fetus or infant, and decisions should be made in consultation with a healthcare professional.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

For alcohol dependence, alternatives such as acamprosate or disulfiram act through different mechanisms, while naltrexone targets opioid receptors to reduce reward. In opioid dependence, naltrexone is an antagonist, contrasting with agonist therapies like methadone or partial agonists such as buprenorphine, which relieve withdrawal but maintain some opioid activity.

Naltrexon-Hcl should be stored at ambient temperature, below 25 °C, in its original packaging to protect it from moisture and light. Keep the product out of reach of children and avoid storing it in areas with high humidity.

The medication is supplied as an oral tablet. Patients should swallow the tablet whole with a glass of water, preferably on an empty stomach, unless otherwise directed by their prescriber.

Serious adverse events include hepatotoxicity, severe depression or suicidal thoughts, and allergic reactions such as rash or angioedema. Prompt medical attention is required if any of these symptoms develop.

Naltrexon-Hcl is contraindicated in patients currently receiving opioid agonist therapy, those with severe hepatic impairment, and individuals with known hypersensitivity to naltrexone or any excipients in the tablet. It should also be used with caution in patients with renal dysfunction.