Product image of Naltrexon Vitaflo (Naltrexone Hydrochloride) supplied by GNH India

Naltrexon Vitaflo

Active Ingredient:
Naltrexone Hydrochloride
Origin:
EU

Naltrexon Vitaflo (Naltrexone Hydrochloride)

Naltrexone Hydrochloride, the active ingredient in Naltrexon Vitaflo, is an opioid antagonist presented as an oral tablet for oral use. It is employed in the management of alcohol dependence and as a maintenance therapy for opioid dependence in adults who have completed detoxification and require ongoing relapse prevention under professional supervision and are monitored regularly.

GNH India supplies Naltrexon Vitaflo as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide with a focus on quality assurance and regulatory compliance.

Manufacturer / TM Owner

Aop Orphan Pharmaceuticals Gmbh

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Indications & Clinical Uses

Naltrexon Vitaflo, an opioid antagonist, is indicated for conditions involving opioid and alcohol pathways.

  • Alcohol dependence: helps reduce cravings and supports sustained abstinence.
  • Opioid dependence (maintenance therapy): blocks opioid receptors to prevent relapse during long‑term treatment.
  • Opioid dependence (detoxification support): used after opioid withdrawal to maintain blockade of opioid effects.

How It Works

  • Naltrexon Vitaflo works by competitively binding to μ, κ, and δ opioid receptors in the central nervous system, preventing endogenous and exogenous opioids from activating these receptors. This antagonism blocks the rewarding and reinforcing effects of alcohol and opioid substances, thereby reducing cravings and helping maintain abstinence in dependent individuals.

Side Effects

Naltrexon Vitaflo may cause a range of adverse reactions, which are categorized by frequency and severity.

Common Side Effects

  • Nausea
  • Headache
  • Dizziness
  • Fatigue

Serious or Rare Side Effects

  • Severe liver injury
  • Suicidal thoughts or worsening depression
  • Allergic reactions, including anaphylaxis

Precautions & Warnings

When prescribing Naltrexon Vitaflo, clinicians should observe several safety precautions to minimize risk.

  • Assess liver function: obtain baseline hepatic enzymes before starting therapy.
  • Monitor mood: watch for signs of depression or suicidal ideation during treatment.
  • Avoid in acute hepatitis: contraindicated in patients with active severe liver disease.
  • Use caution in renal impairment: adjust dosing if significant kidney dysfunction is present.
  • Store at ambient temperature: keep in original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Naltrexon Vitaflo can interact with other medicines; awareness of major and moderate interactions helps ensure safe use.

Major Interactions (Avoid)

  • Opioid agonists: concurrent use precipitates acute withdrawal.
  • Alcohol: may increase central nervous system depression.
  • Disulfiram: combined use can heighten risk of hepatotoxicity.

Moderate Interactions (Monitor Closely)

  • Benzodiazepines: may enhance sedative effects.
  • Selective serotonin reuptake inhibitors: monitor for possible serotonin syndrome.
  • CYP3A4 inhibitors: may raise naltrexone plasma concentrations.

Frequently Asked Questions

Naltrexon Vitaflo is prescribed for adults with alcohol dependence to help reduce cravings and support abstinence, and for opioid dependence as a maintenance therapy to block opioid effects and prevent relapse after detoxification.

Naltrexone Hydrochloride acts as a competitive antagonist at μ, κ, and δ opioid receptors. By occupying these receptors, it blocks the action of both endogenous opioids and external opioid substances, diminishing the rewarding sensations that drive alcohol and opioid use.

The specific dose and dosing schedule of Naltrexon Vitaflo are determined by the prescribing clinician based on the individual’s medical condition, treatment goals, and response to therapy. Patients should follow the prescriber’s instructions exactly.

The safety of Naltrexon Vitaflo in pregnancy and lactation has not been definitively established. Healthcare providers should weigh potential benefits against unknown risks and consider alternative therapies when treating pregnant or nursing individuals.

To request Naltrexon Vitaflo, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Naltrexon Vitaflo contains the same active ingredient, naltrexone hydrochloride, as other branded or generic opioid antagonists. Its clinical profile, including efficacy in reducing cravings and blocking opioid receptors, is comparable, though formulation differences such as tablet size or excipients may vary between products.

Naltrexon Vitaflo should be stored at ambient temperature, below 25 °C, in its original packaging. Protect the product from moisture, direct sunlight, and extreme temperature fluctuations to maintain its stability and potency.

Naltrexon Vitaflo is taken orally, typically as a tablet swallowed with water. The exact timing relative to meals or other medications is determined by the prescriber, who will provide detailed administration instructions.

Serious risks include severe liver injury, worsening depression or emergence of suicidal thoughts, and rare allergic reactions such as anaphylaxis. Patients should be monitored regularly for hepatic function and mental health changes, and any signs of an allergic response require immediate medical attention.

Naltrexon Vitaflo is contraindicated in individuals with acute hepatitis, severe liver disease, or those currently using opioid agonists, as it can precipitate withdrawal. It should also be avoided in patients with known hypersensitivity to naltrexone or any of the tablet’s excipients.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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