Product image of Naltrexon Vitaflo (Naltrexone Hydrochloride) supplied by GNH India

Naltrexon Vitaflo

Active Ingredient:
Naltrexone Hydrochloride
Origin:
EU

Naltrexon Vitaflo (Naltrexone Hydrochloride)

Naltrexone, the active ingredient in Naltrexon Vitaflo, is an opioid antagonist presented as an oral tablet for oral use. It is employed in the treatment of alcohol dependence and opioid dependence, helping to reduce cravings and prevent relapse in adults.
GNH India supplies Naltrexon Vitaflo as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Aop Orphan Pharmaceuticals Gmbh

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Indications & Clinical Uses

Naltrexon Vitaflo is an opioid antagonist used in the management of disorders related to alcohol and opioid use.

  • Alcohol dependence: reduces cravings and helps maintain abstinence.
  • Opioid dependence: blocks opioid effects to prevent relapse and supports detoxification.
  • Substance use disorder: assists in managing dependence on both alcohol and opioids.

How It Works

  • Naltrexone acts as a competitive antagonist at the mu, kappa, and delta opioid receptors. By binding to these receptors without activating them, it blocks the effects of both endogenous opioids and exogenous opioid substances, thereby diminishing the rewarding and reinforcing properties that contribute to dependence and relapse.

Side Effects

Naltrexon Vitaflo may be associated with a range of adverse reactions.

Common Side Effects

  • Nausea: mild to moderate upset stomach.
  • Headache: transient cranial discomfort.
  • Dizziness: occasional light‑headed sensation.
  • Fatigue: feeling unusually tired.
  • Insomnia: difficulty falling or staying asleep.

Serious or Rare Side Effects

  • Hepatotoxicity: signs of liver injury such as jaundice.
  • Severe depression or suicidal thoughts: emergent mood changes requiring immediate attention.
  • Allergic reactions: rash, swelling, or anaphylaxis in rare cases.

Precautions & Warnings

Before initiating therapy, several safety considerations should be reviewed.

  • Liver function assessment: evaluate hepatic enzymes prior to use.
  • Depression monitoring: watch for worsening mood or suicidal ideation.
  • Acute opioid withdrawal: avoid initiating in patients currently dependent on opioids.
  • Renal impairment: adjust use in patients with reduced kidney function.
  • Concomitant medications: review for potential interactions.
  • Store at ambient temperature: keep in the original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Naltrexon Vitaflo can interact with several drug classes, requiring careful management.

Major Interactions (Avoid)

  • Opioid analgesics: may precipitate acute withdrawal.
  • Benzodiazepines: increased risk of sedation and respiratory depression.
  • Disulfiram: combined hepatotoxic potential.

Moderate Interactions (Monitor Closely)

  • Antidepressants (especially SSRIs): monitor for serotonin syndrome.
  • Hepatotoxic agents (e.g., isoniazid): observe liver function regularly.

Frequently Asked Questions

Naltrexon Vitaflo is a prescription opioid antagonist indicated for the management of alcohol dependence and opioid dependence. It helps reduce cravings, supports abstinence, and lowers the risk of relapse in adults undergoing treatment for these substance‑use disorders.

Naltrexone works by competitively binding to mu, kappa, and delta opioid receptors without activating them. This blockade prevents both endogenous opioids and external opioid drugs from stimulating the receptors, thereby diminishing the rewarding effects that drive dependence and relapse.

The appropriate dose of Naltrexon Vitaflo is determined by the prescribing clinician based on the individual patient's condition, treatment goals, and medical history. Specific dosing regimens are not provided here and should be obtained from a qualified healthcare professional.

Safety data for Naltrexon Vitaflo in pregnancy and lactation are limited. It should only be used if the potential benefit justifies any possible risk to the fetus or infant, and this decision must be made in consultation with a qualified healthcare provider.

To order Naltrexon Vitaflo, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams worldwide, and will request verification of trade or institutional credentials before providing pricing, availability, shipping details, and any necessary import documentation.

Compared with alternatives such as acamprosate for alcohol dependence or methadone/buprenorphine for opioid dependence, Naltrexon Vitaflo offers a non‑opioid, antagonist‑based approach that blocks opioid receptors rather than activating them. This can be advantageous for patients seeking abstinence without the risk of additional opioid exposure, though individual response and tolerability vary.

Naltrexon Vitaflo should be stored at ambient temperature, preferably below 25 °C. Keep the tablets in their original packaging, protect them from moisture and direct sunlight, and ensure the container is tightly closed to maintain product stability.

Naltrexon Vitaflo is supplied as oral tablets intended for swallowing whole with water. It is typically taken once daily, although the exact schedule is set by the prescribing clinician based on the therapeutic plan.

The most serious risks include potential liver injury, severe depression, and suicidal thoughts or behaviors. Patients should be monitored regularly for signs of hepatic dysfunction and mood changes, and any concerning symptoms should prompt immediate medical evaluation.

Naltrexon Vitaflo is contraindicated in individuals with acute opioid intoxication, severe hepatic impairment, or known hypersensitivity to naltrexone or any excipients. It should also be used with caution in patients with uncontrolled psychiatric conditions or those currently undergoing opioid withdrawal.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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