Product image of Nambrol Bambini (Flunisolide) supplied by GNH India

Nambrol Bambini

Active Ingredient:
Flunisolide
Origin:
EU

Nambrol Bambini (Flunisolide)

Flunisolide, the active ingredient in Nambrol Bambini, is a corticosteroid presented as an inhalation for inhalation use. It treats asthma and allergic rhinitis in patients who need anti‑inflammatory control of the airways.

GNH India supplies Nambrol Bambini as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Lanova Farmaceutici S.R.L.

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Indications & Clinical Uses

Flunisolide is an inhaled glucocorticoid that acts on airway inflammation and allergic nasal mucosa.

  • Asthma: reduces airway inflammation, improves symptom control and decreases frequency of exacerbations.
  • Allergic rhinitis: decreases nasal inflammation, relieving congestion, sneezing and itching.
  • Exercise‑induced bronchoconstriction: provides preventive anti‑inflammatory protection before physical activity.

How It Works

  • Flunisolide binds to intracellular glucocorticoid receptors, forming a complex that translocates to the nucleus and modulates gene transcription. This down‑regulates pro‑inflammatory cytokine production, inhibits inflammatory cell recruitment, and suppresses airway and nasal mucosal inflammation, leading to improved respiratory function.

Side Effects

Flunisolide may cause a range of adverse reactions, most of which are related to local airway exposure.

Common Side Effects

  • Throat irritation or soreness.
  • Hoarseness or voice changes.
  • Cough or wheezing after inhalation.
  • Oral candidiasis (thrush).
  • Headache.
  • Nasal dryness or irritation.

Serious or Rare Side Effects

  • Adrenal suppression with systemic effects.
  • Glaucoma or cataract formation with prolonged use.
  • Severe allergic reactions, including anaphylaxis.
  • Pneumonia or opportunistic infections.
  • Paradoxical bronchospasm immediately after inhalation.

Precautions & Warnings

When prescribing or using Flunisolide inhalation, consider the following safety measures.

  • Infection risk: monitor for signs of respiratory infection and treat promptly.
  • Growth monitoring: assess growth velocity in pediatric patients during long‑term therapy.
  • Spacer use: recommend a spacer device to reduce oropharyngeal deposition.
  • Discontinuation: avoid abrupt cessation after prolonged high‑dose use; taper as advised.
  • Oral hygiene: rinse mouth and gargle after each inhalation to prevent candidiasis.
  • Store at ambient temperature: keep in original packaging, protect from moisture and direct heat.

Avoid Interactions

Flunisolide can interact with other medicines, altering efficacy or safety.

Major Interactions (Avoid)

  • Strong CYP3A4 inhibitors (e.g., ketoconazole, itraconazole): may increase systemic exposure.
  • Systemic corticosteroids: additive risk of adrenal suppression.
  • Live vaccines: immunosuppression may reduce vaccine effectiveness.

Moderate Interactions (Monitor Closely)

  • Antifungal agents (e.g., fluconazole): may modestly raise flunisolide levels.
  • Diuretics: monitor electrolytes as glucocorticoids can affect potassium balance.
  • Beta‑agonists: possible reduced bronchodilator response; adjust therapy if needed.

Frequently Asked Questions

Nambrol Bambini contains flunisolide, an inhaled corticosteroid indicated for the maintenance treatment of asthma and for controlling symptoms of allergic rhinitis. It helps reduce airway inflammation and nasal congestion, providing long‑term control of these respiratory conditions.

Flunisolide binds to glucocorticoid receptors inside airway cells, altering gene transcription. This reduces the production of inflammatory cytokines, limits immune‑cell infiltration, and suppresses swelling in the bronchial and nasal mucosa, thereby improving airflow and reducing allergic symptoms.

The specific dose and frequency of Nambrol Bambini are determined by the prescribing healthcare professional based on the patient’s age, severity of disease, and response to therapy. Patients should follow the prescriber’s instructions and the product’s label.

Safety data for flunisolide in pregnancy and lactation are limited. The prescriber should weigh the potential benefits against any possible risks to the fetus or infant. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss use with their healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Flunisolide is a medium‑potency inhaled corticosteroid similar in efficacy to agents such as budesonide or beclomethasone. Choice among inhaled steroids often depends on device preference, dosing convenience, patient response, and formulary considerations rather than large differences in clinical effect.

Store Nambrol Bambini at ambient temperature, below 25 °C (77 °F). Keep the inhaler in its original packaging, protect it from moisture, direct sunlight and extreme heat to maintain product stability and performance.

Nambrol Bambini is delivered via inhalation using the supplied inhaler device. The patient inhales the prescribed number of puffs, preferably using a spacer if recommended, and should rinse the mouth after each use to reduce the risk of oral thrush.

Serious risks, though uncommon, include adrenal suppression, glaucoma or cataract development with long‑term use, severe allergic reactions such as anaphylaxis, and paradoxical bronchospasm immediately after inhalation. Patients should report any unusual symptoms to their healthcare provider promptly.

Nambrol Bambini should be avoided in individuals with known hypersensitivity to flunisolide or any component of the inhaler. It is also contraindicated in patients with untreated active infections of the respiratory tract or those who have experienced severe paradoxical bronchospasm with inhaled steroids.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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