Product image of Nano-Albumon (Human Serum Albumin) supplied by GNH India

Nano-Albumon

Active Ingredient:
Human Serum Albumin
Origin:
EU

Nano-Albumon (Human Serum Albumin)

Human Serum Albumin, the active ingredient in Nano-Albumon, is a protein solution presented as a sterile solution for intravenous and subcutaneous use. It increases plasma oncotic pressure, expanding intravascular volume for patients needing rapid volume replacement such as those with acute blood loss or severe hypoalbuminemia.

GNH India supplies Nano-Albumon as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide.

Manufacturer / TM Owner

Medi-Radiopharma Kft.

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Indications & Clinical Uses

Nano-Albumon is used to restore and maintain plasma volume in clinical situations where fluid loss or low albumin levels are present.

  • Acute hypovolemia: supports rapid intravascular volume expansion after severe blood loss or trauma.
  • Burn injuries: helps replace lost plasma proteins and maintain oncotic pressure.
  • Hypoalbuminemia associated with liver cirrhosis: improves oncotic balance and reduces edema.
  • Major surgery: assists in maintaining circulatory stability during extensive operative procedures.

How It Works

  • Human Serum Albumin acts as a colloidal osmotic agent in the bloodstream. By increasing plasma oncotic pressure, it draws water from the interstitial space into the vascular compartment, thereby expanding intravascular volume and supporting hemodynamic stability in patients with fluid deficits or low endogenous albumin levels.

Side Effects

Human Serum Albumin may be associated with a range of adverse reactions.

Common Side Effects

  • Fever or chills during infusion.
  • Mild hypotension or hypertension.
  • Localized pain or erythema at the injection site.
  • Nausea or vomiting.
  • Headache.
  • Transient increase in serum bilirubin.

Serious or Rare Side Effects

  • Anaphylactic or severe allergic reactions.
  • Acute lung injury or pulmonary edema.
  • Thromboembolic events.
  • Hemolysis.
  • Renal dysfunction.
  • Transmission of infectious agents (very rare).

Precautions & Warnings

When using Nano-Albumon, clinicians should consider several safety measures.

  • Patient assessment: evaluate volume status and serum albumin levels before administration.
  • Infusion rate: administer slowly to reduce risk of cardiovascular overload.
  • Monitoring: observe vital signs and signs of allergic reaction during and after infusion.
  • Contraindications: avoid in patients with known hypersensitivity to human albumin products.
  • Caution in renal or cardiac failure: adjust volume administered accordingly.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Human Serum Albumin can interact with other therapies, influencing efficacy or safety.

Major Interactions (Avoid)

  • Diuretics: may exacerbate hypovolemia if volume expansion is insufficient.
  • ACE inhibitors or ARBs: increased risk of hypotension when combined with rapid volume expansion.

Moderate Interactions (Monitor Closely)

  • Anticoagulants: altered plasma protein binding may affect drug levels.
  • Immunosuppressants: potential for altered distribution due to changes in plasma protein binding.
  • Certain antibiotics (e.g., aminoglycosides): monitor renal function as volume status changes can impact clearance.

Frequently Asked Questions

Nano-Albumon is a sterile solution of Human Serum Albumin used to increase plasma oncotic pressure and expand intravascular volume. It is indicated for conditions such as acute hypovolemia, severe burns, hypoalbuminemia related to liver disease, and during major surgical procedures where rapid volume replacement is required.

Human Serum Albumin functions as a colloidal osmotic agent. By raising the oncotic pressure within the bloodstream, it draws fluid from the interstitial spaces into the vascular compartment, thereby expanding circulating blood volume and supporting hemodynamic stability in patients with fluid deficits or low endogenous albumin.

The dosage of Nano-Albumon is individualized and determined by the prescribing clinician based on the patient’s clinical condition, serum albumin level, and required volume expansion. Healthcare professionals calculate the appropriate volume and infusion rate according to established medical guidelines.

Safety data for Human Serum Albumin in pregnancy and lactation are limited. It should only be used if the potential benefit to the mother outweighs any possible risk to the fetus or infant, and the decision must be made by a qualified healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain handling if needed), and import documentation.

Nano-Albumon provides oncotic pressure expansion, unlike crystalloid solutions that act primarily through volume. Compared with synthetic colloids, Human Serum Albumin has a lower risk of coagulopathy and renal impairment, but it is more expensive and requires careful handling to maintain sterility and protein integrity.

Nano-Albumon must be stored at 2‑8 °C in a refrigerator. It should be kept in its original packaging, protected from light, and must not be frozen or shaken. Maintaining the cold chain is essential to preserve protein stability and efficacy.

Nano-Albumon is administered intravenously or subcutaneously by a qualified healthcare professional. The infusion should be given slowly, with continuous monitoring of vital signs, to avoid rapid shifts in plasma volume and reduce the risk of adverse reactions.

Serious risks include anaphylactic reactions, acute lung injury or pulmonary edema, thromboembolic events, hemolysis, and rare transmission of infectious agents. Prompt recognition and management of these events are critical, and patients should be observed closely during and after infusion.

Nano-Albumon is contraindicated in individuals with known hypersensitivity to human albumin products. Caution is advised for patients with severe cardiac or renal failure, uncontrolled hypertension, or those at high risk for thromboembolic disease, unless the benefits clearly outweigh the risks.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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