Product image of Nanoalbumon (Human Serum Albumin) supplied by GNH India

Nanoalbumon

Active Ingredient:
Human Serum Albumin
Origin:
EU

Nanoalbumon (Human Serum Albumin)

Human Serum Albumin, the active ingredient in Nanoalbumon, is an albumin presented as an unknown/unknown for intravenous use. It restores plasma oncotic pressure and expands intravascular volume in patients who require rapid volume replacement, such as those with hypovolemia or severe burns.

GNH India supplies Nanoalbumon as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide.

Manufacturer / TM Owner

Radiopharmacy Laboratórium Kft.

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Indications & Clinical Uses

Nanoalbumon, a human serum albumin solution, is used in clinical situations that require plasma volume expansion and oncotic support.

  • Hypovolemia: restores circulating volume and improves tissue perfusion.
  • Burn injuries: provides oncotic pressure to reduce edema and support fluid resuscitation.
  • Major surgery: maintains intravascular volume and stabilises haemodynamics.
  • Trauma: helps counteract blood loss and supports circulatory stability.
  • Severe hypoalbuminemia: raises serum albumin levels and improves oncotic balance.

How It Works

  • Human Serum Albumin acts as a natural plasma protein that contributes to oncotic pressure. When administered intravenously, it remains in the intravascular compartment, drawing water from the interstitial space into the bloodstream, thereby expanding plasma volume and supporting circulatory stability in conditions of fluid loss or low albumin levels.

Side Effects

Human Serum Albumin may be associated with a range of adverse reactions, most of which are related to infusion and immune response.

Common Side Effects

  • Fever or chills during infusion.
  • Transient hypotension or hypertension.
  • Mild allergic rash or urticaria.
  • Nausea or vomiting.
  • Headache.
  • Local site irritation.

Serious or Rare Side Effects

  • Anaphylactic or severe allergic reaction.
  • Volume overload leading to pulmonary edema.
  • Hemolysis.
  • Thromboembolic events.
  • Sepsis from contaminated product.
  • Acute renal failure.

Precautions & Warnings

When using Nanoalbumon, clinicians should observe several safety measures to minimise risk.

  • Allergy assessment: confirm no known hypersensitivity to human albumin.
  • Volume status: monitor for signs of fluid overload, especially in cardiac patients.
  • Cardiac function: use cautiously in heart failure or ischemic heart disease.
  • Renal function: adjust monitoring in patients with renal impairment.
  • Electrolyte balance: check serum electrolytes before and during therapy.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Human Serum Albumin can influence the pharmacokinetics of several co‑administered drugs.

Major Interactions (Avoid)

  • Diuretics: may exacerbate intravascular volume depletion.
  • Cardiovascular agents (e.g., nitrates): risk of profound hypotension.

Moderate Interactions (Monitor Closely)

  • Anticoagulants (e.g., warfarin): albumin binding may alter INR, requiring monitoring.
  • Nephrotoxic drugs (e.g., aminoglycosides): monitor renal function closely.
  • Vasopressors: dose adjustments may be needed due to changes in plasma volume.

Frequently Asked Questions

Nanoalbumon is a sterile intravenous solution of human serum albumin used as a plasma volume expander. It helps restore intravascular volume and oncotic pressure in patients with hypovolemia, severe burns, major surgery, trauma, or marked hypoalbuminemia.

Human serum albumin is the main protein responsible for maintaining plasma oncotic pressure. When infused, it stays largely within the vascular space, pulling water from the interstitial fluid into the bloodstream, thereby expanding plasma volume and supporting circulatory stability.

The dose of Nanoalbumon is individualized by the prescribing clinician based on the patient’s weight, clinical condition, and target plasma albumin level. Dosage calculations consider the severity of volume loss and the desired oncotic effect.

Human serum albumin is a naturally occurring protein, and limited data suggest it does not cross the placenta in harmful amounts. However, because safety data are insufficient, the product should be used in pregnancy or lactation only if clearly needed and after risk‑benefit assessment by the healthcare provider.

To order Nanoalbumon, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if required) and necessary import documentation.

Nanoalbumon (human serum albumin) provides oncotic support similar to other albumin products but differs from synthetic colloids such as hydroxyethyl starch, which have distinct safety profiles. Albumin is a natural protein with a lower risk of coagulopathy and renal impairment, making it a preferred choice in many clinical scenarios.

Nanoalbumon should be stored at 2‑8 °C in a refrigerator, protected from light, and must not be frozen or shaken. Before administration, inspect the solution for particulate matter or discoloration and allow it to reach room temperature if required by the infusion protocol.

Nanoalbumon is administered intravenously, typically as an infusion over a period determined by the prescriber. The infusion rate may be adjusted based on the patient’s hemodynamic response, and vital signs should be monitored throughout the administration.

Serious risks include anaphylactic reactions, volume overload leading to pulmonary edema, hemolysis, and rare cases of sepsis from contaminated product. Prompt recognition of these events and immediate medical intervention are essential.

Nanoalbumon is contraindicated in patients with known hypersensitivity to human serum albumin or any component of the formulation. Caution is also advised for individuals with severe heart failure, uncontrolled hypertension, or active pulmonary edema, where additional volume may be harmful.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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