Product image of Nanohsa (Human Albumin Solution) supplied by GNH India

Nanohsa

Active Ingredient:
Human Albumin Solution
Origin:
EU

Nanohsa (Human Albumin Solution)

Human Albumin, the active ingredient in Nanohsa, is a human albumin presented as a solution for injection for intradermal, intratumoral, and subcutaneous use. It is used to treat hypovolemia and hypoalbuminemia in patients requiring plasma volume expansion.

GNH India supplies Nanohsa as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Rotop Pharmaka Gmbh

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Indications & Clinical Uses

Nanohsa (human albumin) is used as a plasma volume expander to manage conditions associated with low intravascular volume or albumin deficiency.

  • Hypovolemia: restores circulating blood volume and improves tissue perfusion.
  • Hypoalbuminemia: raises serum albumin levels to maintain oncotic pressure.
  • Acute liver failure: supports plasma oncotic balance while awaiting liver support.

How It Works

  • Human albumin increases plasma oncotic pressure by contributing to the colloid osmotic gradient, which draws water from the interstitial space into the vascular compartment. This expansion of intravascular volume improves circulatory stability and supports tissue perfusion. The protein also binds endogenous and exogenous substances, aiding transport and distribution.

Side Effects

Human albumin may cause a range of adverse reactions, from mild to severe. Monitoring during and after administration is essential.

Common Side Effects

  • Fever or chills
  • Mild hypotension
  • Headache
  • Nausea or vomiting

Serious or Rare Side Effects

  • Anaphylactic reaction
  • Volume overload leading to pulmonary edema
  • Thromboembolic events
  • Hemolysis or severe hemolytic transfusion reaction

Precautions & Warnings

Human albumin should be administered with careful clinical assessment and monitoring.

  • Assess volume status: evaluate fluid balance before infusion.
  • Monitor for allergic reactions: observe for rash, urticaria, or anaphylaxis.
  • Caution in heart failure: avoid excessive volume expansion.
  • Use cautiously in renal impairment: adjust volume as needed.
  • Do not exceed recommended volume: follow prescriber guidance.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Human albumin can interact with other therapies that affect fluid balance or coagulation.

Major Interactions (Avoid)

  • Concurrent use with other volume expanders may cause circulatory overload.
  • Co‑administration with high‑dose diuretics can precipitate severe hypovolemia.
  • Simultaneous infusion with blood products may increase risk of volume overload.

Moderate Interactions (Monitor Closely)

  • Anticoagulants: monitor coagulation parameters as albumin may alter plasma volume.
  • Nephrotoxic agents: adjust dosing to avoid renal stress.
  • Vasopressors: observe hemodynamic response during volume expansion.

Frequently Asked Questions

Nanohsa contains human albumin and is used as a plasma volume expander to treat conditions such as hypovolemia and hypoalbuminemia, helping to restore intravascular volume and maintain oncotic pressure in patients who need fluid support.

Human albumin increases plasma oncotic pressure, drawing water from the interstitial space into the bloodstream. This expands the circulating blood volume, improves tissue perfusion, and supports the transport of various substances throughout the body.

The dose of Nanohsa is determined by the prescribing clinician based on the patient’s clinical condition, weight, and required volume expansion. The prescriber will calculate the appropriate volume to administer.

The safety of Nanohsa in pregnancy or while breastfeeding has not been definitively established. Clinicians should weigh potential benefits against possible risks and consider alternative therapies when appropriate.

To order Nanohsa, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed), and import documentation.

Nanohsa provides natural human albumin, which offers oncotic support and binding capacity not present in synthetic colloids. Compared with crystalloids, albumin expands plasma volume more efficiently with less total fluid required, but it is generally more expensive and requires careful monitoring for volume overload.

Nanohsa should be stored at 2‑8 °C in a refrigerator, protected from light. Do not freeze or shake the solution. Keep the vial in its original packaging until use to maintain sterility and stability.

Nanohsa is supplied as a sterile solution for injection and can be given via intradermal, intratumoral, or subcutaneous routes, depending on the clinical indication. Administration is performed by qualified healthcare professionals under aseptic conditions.

Serious risks include anaphylactic reactions, volume overload leading to pulmonary edema, and thromboembolic events. Patients should be closely monitored for signs of respiratory distress, sudden hypotension, or unexpected swelling during and after infusion.

Nanohsa should be avoided in patients with known hypersensitivity to human albumin, uncontrolled heart failure, severe renal impairment where fluid overload is a concern, or in those where volume expansion could exacerbate existing conditions.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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