Product image of Nanoscan (Human Serum Albumin) supplied by GNH India

Nanoscan

Active Ingredient:
Human Serum Albumin
Origin:
EU

Nanoscan (Human Serum Albumin)

Human Serum Albumin, the active ingredient in Nanoscan, is a plasma protein presented as a sterile solution for intravenous and subcutaneous use. It restores plasma oncotic pressure and is employed to treat hypoalbuminemia and to expand intravascular volume in patients with hypovolemia or fluid loss.

GNH India supplies Nanoscan as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Radiopharmacy Laboratórium Kft.

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Indications & Clinical Uses

Nanoscan is used to address conditions where plasma protein replacement or volume expansion is required.

  • Hypoalbuminemia: raises serum albumin levels and improves oncotic pressure.
  • Acute hypovolemia: expands intravascular volume to support circulatory stability.
  • Major burns: provides protein support and fluid balance during resuscitation.
  • Liver disease with ascites: helps maintain oncotic pressure and reduces fluid accumulation.

How It Works

  • Human Serum Albumin acts as an exogenous plasma protein that increases oncotic pressure within the vascular compartment. By binding water and various endogenous substances, it draws fluid from the interstitial space into the circulation, thereby expanding intravascular volume and supporting hemodynamic stability in patients with low albumin or fluid loss.

Side Effects

Adverse reactions may occur with albumin administration and are categorized by frequency.

Common Side Effects

  • Fever or chills
  • Rash or urticaria
  • Headache
  • Nausea or vomiting
  • Mild hypotension
  • Transient hypertension

Serious or Rare Side Effects

  • Anaphylactic or severe allergic reaction
  • Pulmonary edema
  • Thromboembolic events
  • Severe hypotension or circulatory collapse
  • Hemolysis
  • Acute renal failure

Precautions & Warnings

Human Serum Albumin should be used with careful clinical monitoring.

  • Fluid balance monitoring: assess volume status before and during infusion.
  • Serum albumin levels: measure to guide dosing and avoid overload.
  • Infusion rate: administer slowly to reduce risk of hypotension.
  • Cardiac or renal impairment: use with caution and monitor closely.
  • Allergy assessment: verify no known hypersensitivity to albumin products.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Albumin can interact with several drug classes, requiring attention to avoid adverse outcomes.

Major Interactions (Avoid)

  • Concurrent diuretics: may precipitate hypovolemia.
  • ACE inhibitors or ARBs: can exacerbate hypotension.
  • Other volume expanders: increase risk of circulatory overload.
  • Blood products: may lead to fluid overload.
  • Agents that increase capillary permeability: amplify fluid shifts.

Moderate Interactions (Monitor Closely)

  • NSAIDs: potential renal function impact.
  • Nephrotoxic antibiotics: monitor kidney parameters.
  • Vasopressors: adjust dosing based on hemodynamic response.
  • Anticoagulants: observe for bleeding changes.
  • Corticosteroids: may affect fluid retention.

Frequently Asked Questions

Nanoscan is a sterile solution of human serum albumin used as a plasma protein replacement and volume expander. It is indicated for patients with hypoalbuminemia, acute hypovolemia, major burns, and certain liver conditions where restoring oncotic pressure and intravascular volume is clinically required.

Human serum albumin increases plasma oncotic pressure by binding water and various endogenous substances. This draws fluid from the interstitial space into the bloodstream, expanding intravascular volume, supporting blood pressure, and improving tissue perfusion in states of low albumin or fluid loss.

The dose of Nanoscan is individualized. A qualified prescriber determines the amount and rate of infusion based on the patient’s serum albumin level, fluid status, and clinical condition. No fixed regimen is provided in public information.

The safety of human serum albumin in pregnancy and lactation has not been definitively established. Use should be considered only if the potential benefit justifies any possible risk to the fetus or infant, and it must be decided by the treating physician.

To order Nanoscan, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed), and necessary import documentation.

Compared with synthetic colloids or crystalloids, human serum albumin provides oncotic pressure similar to natural plasma proteins, resulting in more efficient intravascular volume expansion with less interstitial edema. However, it is more costly and requires careful monitoring for rare allergic reactions.

Nanoscan should be stored at 2‑8 °C, protected from light, and must not be frozen or shaken. Before use, inspect the solution for particulate matter or discoloration and allow it to reach room temperature if required for administration.

Nanoscan is administered by intravenous or subcutaneous injection. The solution is typically infused slowly through a calibrated infusion set, with the rate adjusted according to the patient’s hemodynamic response and clinical guidelines provided by the prescriber.

Serious risks include anaphylactic reactions, pulmonary edema, severe hypotension or circulatory collapse, thromboembolic events, hemolysis, and acute renal failure. Prompt recognition and management of these events are essential, and patients should be monitored closely during and after infusion.

Nanoscan is contraindicated in patients with known hypersensitivity to human serum albumin or any component of the formulation. Caution is advised in individuals with severe heart failure, uncontrolled hypertension, or active pulmonary edema, where volume expansion could worsen the condition.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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