Nanoscan (Human Serum Albumin)

Nanoscan provides human serum albumin for clinical situations that require plasma volume support or correction of low albumin levels.

• Hypoalbuminemia: restores normal serum albumin concentrations and improves oncotic pressure.
• Acute hypovolemia: expands intravascular volume when rapid fluid replacement is needed.
• Burn or trauma resuscitation: supports fluid balance and protein loss in severe injury.
• Peri‑operative care: maintains plasma volume and oncotic stability during major surgery.

• Human Serum Albumin acts as the principal plasma protein responsible for maintaining colloid oncotic pressure. When administered intravenously or subcutaneously, it expands the intravascular compartment by drawing water into the circulation and binds endogenous and exogenous substances, thereby contributing to fluid balance, transport of fatty acids, hormones, and drugs, and modulation of vascular permeability.

Human Serum Albumin may be associated with a range of adverse reactions, from mild to severe.

Common Side Effects

• Fever or chills
• Mild rash or urticaria
• Headache
• Nausea or vomiting
• Transient hypotension
• Dizziness

Serious or Rare Side Effects

• Anaphylactic reaction
• Severe hypotension or shock
• Volume overload leading to pulmonary edema
• Hemolysis
• Transmission of infectious agents
• Acute renal failure

When using Nanoscan, clinicians should observe several safety measures.

• Assess baseline albumin and fluid status: determine need for replacement.
• Monitor vital signs and fluid balance: watch for signs of overload.
• Evaluate cardiac function: use cautiously in heart failure.
• Review renal function: adjust use in renal impairment.
• Check for known albumin hypersensitivity: avoid if allergic.
• Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Human Serum Albumin can interact with other therapies, influencing fluid balance and drug distribution.

Major Interactions (Avoid)

• Concurrent use of multiple albumin products: risk of volume overload.
• Known hypersensitivity to albumin preparations.

Moderate Interactions (Monitor Closely)

• Loop diuretics: may exacerbate electrolyte shifts.
• ACE inhibitors or ARBs: can potentiate hypotensive effects.
• NSAIDs: may affect renal perfusion when combined with albumin.
• Blood products: consider cumulative volume load.
• Certain antibiotics (e.g., aminoglycosides): albumin binding may alter plasma levels.