Product image of Naprosyn Ec (Naproxen) supplied by GNH India

Naprosyn Ec

Active Ingredient:
Naproxen
Origin:
EU

Naprosyn Ec (Naproxen)

Naproxen, the active ingredient in Naprosyn Ec, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an enteric‑coated tablet for oral use. It treats mild to moderate pain, inflammatory conditions such as rheumatoid arthritis and osteoarthritis, dysmenorrhea, and gout flares in adults, and is commonly prescribed for short‑term symptom relief.

GNH India supplies Naprosyn Ec as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Atnahs Pharma Netherlands B.V.

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Indications & Clinical Uses

Naproxen is an NSAID that reduces inflammation and pain by inhibiting cyclooxygenase enzymes.

  • Rheumatoid arthritis: reduces joint inflammation and pain, improving mobility.
  • Osteoarthritis: alleviates chronic joint discomfort and stiffness.
  • Dysmenorrhea: lessens menstrual cramps and associated pelvic pain.
  • Gout flares: decreases acute joint inflammation and tenderness.
  • Mild to moderate pain: provides analgesia for headaches, dental pain, and musculoskeletal aches.

How It Works

  • Naproxen reversibly inhibits both cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, which blocks the conversion of arachidonic acid to prostaglandins. The resulting reduction in prostaglandin synthesis diminishes inflammation, pain signaling, and fever generation, producing its analgesic, anti‑inflammatory, and antipyretic effects.

Side Effects

Adverse reactions may occur with naproxen therapy.

Common Side Effects

  • Gastrointestinal discomfort or dyspepsia.
  • Headache.
  • Dizziness.
  • Mild skin rash.
  • Elevated blood pressure.
  • Nausea.

Serious or Rare Side Effects

  • Gastrointestinal ulceration or bleeding.
  • Cardiovascular events such as myocardial infarction or stroke.
  • Severe skin reactions (e.g., Stevens‑Johnson syndrome).
  • Hepatic enzyme elevation or liver injury.
  • Acute renal impairment or failure.
  • Anaphylaxis or severe hypersensitivity reactions.

Precautions & Warnings

Before initiating naproxen, consider the following safety measures.

  • Assess gastrointestinal risk: evaluate history of ulcers or bleeding.
  • Monitor renal function: check creatinine in patients with kidney disease.
  • Avoid use in late pregnancy: NSAIDs are contraindicated in the third trimester.
  • Use the lowest effective dose: limit duration to reduce adverse events.
  • Avoid concomitant anticoagulants: increased risk of bleeding.
  • Store at ambient temperature: keep in the original pack, protect from moisture.

Avoid Interactions

Naproxen can interact with several medicines; awareness helps prevent complications.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): heightened bleeding risk.
  • Other NSAIDs or aspirin: additive gastrointestinal toxicity.
  • Selective serotonin reuptake inhibitors (SSRIs): increased hemorrhage potential.
  • Lithium: naproxen may raise lithium concentrations.
  • Methotrexate: reduced clearance leading to toxicity.

Moderate Interactions (Monitor Closely):\n- ACE inhibitors or ARBs: possible reduction in renal function.

  • Diuretics: may enhance renal adverse effects.
  • Beta‑blockers: potential attenuation of antihypertensive effect.
  • Corticosteroids: synergistic risk of gastrointestinal ulceration.
  • Antihypertensive agents: monitor blood pressure control.

Frequently Asked Questions

Naprosyn Ec contains naproxen, an NSAID indicated for the relief of mild to moderate pain, reduction of inflammation in rheumatoid arthritis and osteoarthritis, treatment of dysmenorrhea, and management of acute gout flares. It is prescribed for adult patients requiring anti‑inflammatory and analgesic therapy.

Naproxen works by reversibly inhibiting the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which blocks the synthesis of prostaglandins. Lower prostaglandin levels reduce inflammation, pain signaling, and fever, providing the therapeutic effects associated with NSAIDs.

The appropriate dose of Naprosyn Ec is determined by the prescribing healthcare professional based on the specific indication, patient age, weight, renal and hepatic function, and overall risk profile. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Naproxen is generally avoided in the third trimester of pregnancy because of potential fetal cardiovascular risks. Use during earlier trimesters should be considered only if the benefit outweighs the risk and under medical supervision. Limited data are available for breastfeeding; a prescriber should evaluate safety before use.

To order Naprosyn Ec, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies and procurement teams across international markets, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Naprosyn Ec (naproxen) has a longer half‑life than ibuprofen, allowing twice‑daily dosing for many patients. Its anti‑inflammatory potency is comparable to diclofenac, while the risk of gastrointestinal irritation is similar across NSAIDs. Choice of agent depends on individual patient risk factors, dosing convenience, and clinician preference.

Naprosyn Ec should be stored at ambient temperature, below 25 °C, in its original packaging to protect from moisture and light. Keep the tablets out of reach of children and do not use if the packaging is damaged or the tablets appear discolored.

Naprosyn Ec is taken orally with a full glass of water. Because it is enteric‑coated, it should be swallowed whole and not crushed or chewed to preserve the coating that reduces gastric irritation. It may be taken with or without food, depending on tolerability.

Serious risks include gastrointestinal bleeding or ulceration, cardiovascular events such as heart attack or stroke, severe skin reactions (e.g., Stevens‑Johnson syndrome), renal impairment, and hypersensitivity reactions including anaphylaxis. Patients should be monitored for signs of these conditions and seek immediate medical attention if they occur.

Naprosyn Ec should be avoided in patients with a known hypersensitivity to naproxen or other NSAIDs, active gastrointestinal ulcer or bleeding, severe heart failure, uncontrolled hypertension, third‑trimester pregnancy, and in individuals taking anticoagulants without close medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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