Product image of Naproxen Ab (Naproxen) supplied by GNH India

Naproxen Ab

Active Ingredient:
Naproxen
Origin:
EU

Naproxen Ab (Naproxen)

Naproxen, the active ingredient in Naproxen Ab, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral tablet for oral use. It treats pain, inflammation, arthritis and dysmenorrhea in adult patients.
GNH India supplies Naproxen Ab as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Aurobindo N.V.

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Indications & Clinical Uses

  • Naproxen is an NSAID that reduces pain and inflammation across several musculoskeletal and gynecologic conditions.
  • Pain: provides relief from mild to moderate acute pain such as headache or dental pain.
  • Inflammation: reduces swelling associated with soft‑tissue injuries.
  • Arthritis: alleviates joint pain and stiffness in osteoarthritis and rheumatoid arthritis.
  • Dysmenorrhea: eases menstrual cramps and related discomfort.

How It Works

  • Naproxen exerts its effect by non‑selectively inhibiting cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, which blocks the conversion of arachidonic acid to prostaglandins. The resulting decrease in prostaglandin synthesis lowers inflammation, pain signaling, and fever responses in the body.

Side Effects

Naproxen may cause a range of adverse reactions, from mild to serious.

Common Side Effects

  • Gastrointestinal discomfort such as nausea, dyspepsia or abdominal pain.
  • Headache or dizziness.
  • Mild skin rash or itching.
  • Elevated blood pressure.
  • Fluid retention or peripheral edema.

Serious or Rare Side Effects

  • Gastrointestinal ulceration or bleeding.
  • Severe liver enzyme elevation or hepatitis.
  • Renal impairment or acute kidney injury.
  • Cardiovascular events such as myocardial infarction or stroke.
  • Severe hypersensitivity reactions including anaphylaxis.

Precautions & Warnings

  • Before using Naproxen, consider the following safety measures.
  • Cardiovascular risk: avoid use in patients with established heart disease or high thrombotic risk.
  • Gastrointestinal history: assess for prior ulcers, bleeding or chronic NSAID use.
  • Renal function: monitor kidney function in patients with existing renal impairment.
  • Concomitant drugs: review use of anticoagulants, other NSAIDs, or corticosteroids.
  • Store at ambient temperature: keep below 25 °C in the original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Naproxen can interact with several drug classes, requiring careful management.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of serious bleeding.
  • Selective COX‑2 inhibitors: additive gastrointestinal toxicity.
  • High‑dose aspirin: heightened bleeding risk.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or diuretics: possible reduction in renal function.
  • Lithium: NSAIDs may raise lithium serum levels.
  • Methotrexate: decreased clearance leading to toxicity.

Frequently Asked Questions

Naproxen Ab is prescribed to manage mild to moderate pain, reduce inflammation, treat various forms of arthritis, and relieve menstrual cramps (dysmenorrhea). It is commonly used in adults for conditions where prostaglandin‑mediated inflammation contributes to symptoms.

Naproxen works by blocking the activity of cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are essential for converting arachidonic acid into prostaglandins. By lowering prostaglandin levels, it diminishes pain signals, reduces swelling, and helps lower fever.

The appropriate dose of Naproxen Ab is determined by the prescribing healthcare professional based on the patient’s condition, age, weight, and response to therapy. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Safety of naproxen during pregnancy or lactation has not been definitively established. It should only be used if the potential benefit justifies the potential risk to the fetus or infant, and only under medical supervision.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Naproxen has a longer half‑life than many NSAIDs such as ibuprofen, allowing for less frequent dosing. Its analgesic and anti‑inflammatory potency is comparable, but individual tolerability and cardiovascular risk profiles may differ, so clinicians choose based on patient‑specific factors.

Naproxen Ab should be stored at ambient temperature, ideally below 25 °C. Keep the tablets in the original container, protect them from moisture, heat and direct sunlight to maintain stability.

Naproxen Ab is taken orally, usually with a full glass of water. It can be taken with or without food, but taking it with food may reduce gastrointestinal discomfort.

Serious risks include gastrointestinal bleeding or ulceration, cardiovascular events such as heart attack or stroke, severe kidney injury, and rare but life‑threatening allergic reactions like anaphylaxis. Patients should seek immediate medical attention if they experience any of these symptoms.

Naproxen Ab is contraindicated in individuals with known hypersensitivity to naproxen or other NSAIDs, active gastrointestinal ulcer disease, severe heart failure, or those who have had a recent coronary artery bypass graft. It should also be avoided in patients on certain anticoagulants without careful monitoring.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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