Product image of Naproxen Aurobindo (Naproxen) supplied by GNH India

Naproxen Aurobindo

Active Ingredient:
Naproxen
Origin:
EU

Naproxen Aurobindo (Naproxen)

Naproxen, the active ingredient in Naproxen Aurobindo, is a Nonsteroidal anti-inflammatory drug (NSAID) presented as an oral tablet for oral use. It treats mild to moderate pain, inflammatory joint conditions, dysmenorrhea and fever in adults.

GNH India supplies Naproxen Aurobindo as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Aurobindo Pharma B.V.

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Indications & Clinical Uses

Naproxen is an NSAID that reduces inflammation and pain by inhibiting cyclooxygenase enzymes.

  • Mild to moderate pain: provides analgesic relief for acute and chronic pain conditions.
  • Osteoarthritis: decreases joint inflammation and improves mobility.
  • Rheumatoid arthritis: helps control inflammatory activity and pain.
  • Dysmenorrhea: alleviates menstrual cramps and associated discomfort.
  • Fever: reduces elevated body temperature.

How It Works

  • Naproxen exerts its effect by non‑selectively inhibiting cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, which blocks the conversion of arachidonic acid to prostaglandins. The reduction in prostaglandin synthesis diminishes inflammation, pain signaling, and fever generation at the site of tissue injury.

Side Effects

Common side effects are generally mild and transient, reflecting the drug’s impact on prostaglandin pathways.

Common Side Effects

  • Gastrointestinal upset: nausea, dyspepsia, or abdominal discomfort.
  • Headache: mild to moderate intensity.
  • Dizziness: occasional light‑headedness.
  • Rash: mild skin irritation or erythema.
  • Elevated blood pressure: modest increase in some patients.

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulceration.
  • Severe skin reactions such as Stevens‑Johnson syndrome.
  • Hepatotoxicity: abnormal liver enzymes.
  • Renal impairment: reduced kidney function.
  • Anaphylaxis: rare but potentially life‑threatening allergic response.

Precautions & Warnings

Before using naproxen, consider the following precautions to minimize risks.

  • Cardiovascular risk: avoid in patients with a history of heart disease or stroke.
  • Gastrointestinal safety: use with caution in individuals with ulcer disease or chronic NSAID use.
  • Renal function: monitor kidney function in patients with existing renal impairment.
  • Asthma: be aware of possible bronchospasm in aspirin‑sensitive asthmatics.
  • Pregnancy and lactation: consult a healthcare professional before use.
  • Store below 25°C: keep in the original packaging, protect from moisture and heat.

Avoid Interactions

Naproxen may interact with other medicines, altering its efficacy or safety profile.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of serious bleeding.
  • Selective COX‑2 inhibitors: additive gastrointestinal toxicity.
  • Lithium: naproxen can raise lithium serum levels.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: may reduce renal function when combined.
  • Diuretics: potential for decreased kidney perfusion.
  • Methotrexate: naproxen can increase methotrexate toxicity.
  • SSRIs or SNRIs: heightened bleeding risk.
  • Corticosteroids: increased gastrointestinal ulcer risk.

Frequently Asked Questions

Naproxen Aurobindo is an oral NSAID indicated for the relief of mild to moderate pain, reduction of inflammation in osteoarthritis and rheumatoid arthritis, treatment of dysmenorrhea (menstrual cramps), and lowering of fever. It is commonly prescribed when a non‑opioid analgesic and anti‑inflammatory effect is required.

Naproxen works by non‑selectively inhibiting the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are essential for converting arachidonic acid into prostaglandins. By lowering prostaglandin levels, naproxen reduces the inflammatory response, diminishes pain signaling, and helps control fever.

The appropriate dose of Naproxen Aurobindo is determined by the prescribing healthcare professional based on the patient’s specific condition, severity of symptoms, age, renal and hepatic function, and any concomitant medications. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Naproxen should be used during pregnancy only if clearly needed and after consulting a healthcare provider, as it may affect fetal cardiovascular development, especially in the third trimester. Limited data are available for breastfeeding, and the drug can pass into milk; therefore, a clinician’s guidance is essential before use.

To order Naproxen Aurobindo, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and the necessary import documentation.

Both naproxen and ibuprofen are NSAIDs that inhibit COX enzymes, but naproxen has a longer half‑life, allowing less frequent dosing, whereas ibuprofen is shorter‑acting. Naproxen may provide more sustained pain control for chronic conditions, while ibuprofen is often chosen for short‑term relief. Safety profiles are similar, though individual tolerability can differ.

Naproxen Aurobindo should be stored below 25 °C in a dry place, protected from moisture and direct sunlight. Keep the product in its original packaging until use, and ensure that the container is tightly closed to maintain stability.

Naproxen Aurobindo is taken orally, usually with a full glass of water. It can be taken with or without food, although taking it with food or milk may reduce gastrointestinal discomfort. The exact timing and frequency are set by the prescriber.

Serious risks include gastrointestinal bleeding or ulceration, cardiovascular events such as heart attack or stroke, severe skin reactions (e.g., Stevens‑Johnson syndrome), renal impairment, and anaphylactic reactions. Patients should seek immediate medical attention if they notice black stools, sudden severe headache, swelling, or rash.

Naproxen Aurobindo should be avoided in individuals with known hypersensitivity to naproxen or other NSAIDs, active gastrointestinal ulcer disease, severe heart failure, uncontrolled hypertension, or those who have had recent coronary artery bypass surgery. It is also contraindicated in patients taking certain anticoagulants without close medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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