Product image of Naproxen Bluefish (Naproxen) supplied by GNH India

Naproxen Bluefish

Active Ingredient:
Naproxen
Origin:
EU

Naproxen Bluefish (Naproxen)

Naproxen, the active ingredient in Naproxen Bluefish, is a Nonsteroidal anti-inflammatory drug (NSAID) presented as a tablet for oral use. It treats pain, inflammation, fever and arthritis in adult patients when prescribed by a qualified health professional.

GNH India supplies Naproxen Bluefish as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Bluefish Pharmaceuticals Ab

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Indications & Clinical Uses

Naproxen is an NSAID that reduces inflammation and pain across several musculoskeletal and febrile conditions.

  • Pain: provides analgesic relief for mild to moderate acute pain.
  • Inflammation: decreases swelling associated with inflammatory disorders.
  • Fever: lowers elevated body temperature in febrile states.
  • Arthritis: alleviates joint pain and stiffness in osteoarthritis and rheumatoid arthritis.

How It Works

  • Naproxen inhibits cyclooxygenase (COX‑1 and COX‑2) enzymes, which reduces the conversion of arachidonic acid to prostaglandins. Lower prostaglandin levels diminish inflammation, pain signaling, and fever generation, producing its therapeutic effects in the targeted tissues.

Side Effects

Naproxen may cause a range of adverse reactions, from mild to serious. Awareness of these effects helps clinicians monitor patients appropriately.

Common Side Effects

  • Gastrointestinal upset: nausea, dyspepsia, or abdominal discomfort.
  • Headache: mild to moderate intensity.
  • Dizziness or vertigo.
  • Skin rash or pruritus.
  • Mild renal function changes.

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulceration.
  • Severe hypersensitivity reactions, including anaphylaxis.
  • Elevated liver enzymes or hepatitis.
  • Cardiovascular events such as myocardial infarction or stroke.
  • Severe renal impairment or failure.

Precautions & Warnings

Before prescribing Naproxen, clinicians should evaluate patient‑specific risk factors and follow safe‑use guidelines.

  • Assess renal function: ensure adequate kidney performance before initiation.
  • Evaluate gastrointestinal risk: avoid in patients with active ulcers or a history of GI bleeding.
  • Use lowest effective dose: limit exposure to the minimum dose required for symptom control.
  • Monitor for cardiovascular risk: be cautious in patients with known heart disease.
  • Avoid in known hypersensitivity: discontinue if allergic reactions occur.
  • Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Naproxen can interact with several drug classes, altering efficacy or safety.

Major Interactions (Avoid)

  • Other NSAIDs: additive risk of gastrointestinal bleeding.
  • Anticoagulants (e.g., warfarin): increased bleeding tendency.
  • Selective COX‑2 inhibitors: heightened cardiovascular risk.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: possible reduction in antihypertensive effect and renal function.
  • Diuretics: may impair renal clearance.
  • Lithium: increased lithium serum concentrations.
  • Methotrexate: reduced clearance leading to toxicity.

Frequently Asked Questions

Naproxen Bluefish is used to relieve mild to moderate pain, reduce inflammation, lower fever, and manage symptoms of osteoarthritis and rheumatoid arthritis. It belongs to the NSAID class and is prescribed when a non‑opioid analgesic is appropriate.

Naproxen blocks the cyclooxygenase enzymes COX‑1 and COX‑2, which are needed to produce prostaglandins. By lowering prostaglandin levels, it diminishes inflammation, pain signaling, and fever responses in the affected tissues.

The specific dose and dosing schedule for Naproxen Bluefish are determined by the prescribing clinician based on the patient’s condition, age, weight, and overall health. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Safety of naproxen during pregnancy and lactation depends on the trimester and clinical circumstances. It is generally avoided in the third trimester and used only if the benefit outweighs the risk. Breastfeeding mothers should consult their healthcare provider before use.

To order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Both naproxen and ibuprofen are NSAIDs that inhibit COX enzymes, but naproxen has a longer half‑life, allowing less frequent dosing. Ibuprofen may have a slightly lower risk of gastrointestinal irritation in short‑term use, while naproxen is often preferred for chronic inflammatory conditions due to its sustained effect.

Store Naproxen Bluefish at ambient temperature, preferably below 25 °C. Keep the tablets in the original packaging, protect them from moisture, heat and direct sunlight to maintain potency throughout the shelf life.

Naproxen Bluefish is taken orally, usually with a full glass of water. It can be taken with or without food, but taking it with food or milk may reduce stomach irritation. Patients should swallow the tablet whole and not crush or chew it.

Serious risks include gastrointestinal bleeding or ulceration, severe allergic reactions such as anaphylaxis, cardiovascular events like heart attack or stroke, and significant renal impairment. Patients should seek immediate medical attention if they experience symptoms such as black stools, severe abdominal pain, swelling, or difficulty breathing.

Individuals with known hypersensitivity to naproxen or other NSAIDs, active gastrointestinal ulcers, severe heart failure, uncontrolled hypertension, or significant renal or hepatic impairment should avoid using Naproxen Bluefish unless specifically directed by a healthcare professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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